Q28EW0

PR
Gene name
tmem87a
Protein name
Transmembrane protein 87A
Names
Species
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
KEGG Pathway
xtr:548811
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

109-179 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q28EW0

Entry ID Method Resolution Chain Position Source
AF-Q28EW0-F1 Predicted AlphaFoldDB

No variants for Q28EW0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q28EW0

No associated diseases with Q28EW0

1 regional properties for Q28EW0

Type Name Position InterPro Accession
domain Chromosome segregation in meiosis protein 3 73 - 153 IPR012923

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
  • Golgi apparatus membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

6 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
Golgi cisterna membrane The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
retrograde transport, endosome to Golgi The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8NBN3 TMEM87A Transmembrane protein 87A Homo sapiens (Human) PR
Q96K49 TMEM87B Transmembrane protein 87B Homo sapiens (Human) PR
Q8BXN9 Tmem87a Transmembrane protein 87A Mus musculus (Mouse) PR
Q8BKU8 Tmem87b Transmembrane protein 87B Mus musculus (Mouse) PR
10 20 30 40 50 60
MAAASFQPLK CLLLWVFFVI TPPVKAVPEP GIWTVPIGSG AGSLFFRKTL YNSTNIKVKL
70 80 90 100 110 120
ISPNCPTPVK LTVKWYLRSH RCYNQFTNLE EVLERHHTNL DTTDNFCKNV SKPDFCDKNE
130 140 150 160 170 180
DKNIDCNKDM HALPTLKMSK LVPKISVNQS AGSKNPLNQM DFDIVARTYQ DGPYLFVLQV
190 200 210 220 230 240
KGDENVKWNL SVTVSMKGPH GFISASDWPL MIFYMVMCIM YILLALLWFI WSACYWKDLL
250 260 270 280 290 300
RIQFWIAAVI FLGMLEKAVY YAEYQNTDNT GVSSHGLLIF AELISSIKRT LARLLVTIVS
310 320 330 340 350 360
LGYGIIKPRL GAVMHRVVGM GVLYFVFAAV EGVMRIIGAK EYDLVLLAGI PLALLDSGLC
370 380 390 400 410 420
WWIFVSLAQT MKTLKLRKNT VKYSLYRHFT NTLIFAILAS IIFMIWRTKK FQLVDCQADW
430 440 450 460 470 480
MELWVDDAYW RFLFFIILLV IMFLWRPSAN NQRYAFTPLI DDSDDEVEEF LVTDHLAEGM
490 500 510 520 530 540
KLRGTKPECN GAPKPPATNI DEDLKWVEEN IPSSFADAAL PVLMDSDEEI MMTKYEMSKI
E