Q7XAP4

PR
Gene name
RSH2 (Os08g0457600, LOC_Os08g35620, OsJ_27564, P0493A04.9)
Protein name
Probable GTP diphosphokinase RSH2, chloroplastic
Names
RelA/SpoT homolog 2, OsRSH2, ppGpp synthetase RSH2
Species
Oryza sativa subsp japonica (Rice)
KEGG Pathway
osa:4345756
EC number
2.7.6.5: Diphosphotransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-224 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7XAP4

Entry ID Method Resolution Chain Position Source
AF-Q7XAP4-F1 Predicted AlphaFoldDB

No variants for Q7XAP4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7XAP4

No associated diseases with Q7XAP4

3 regional properties for Q7XAP4

Type Name Position InterPro Accession
domain HD/PDEase domain 239 - 369 IPR003607
domain HD domain 243 - 347 IPR006674
domain RelA/SpoT 425 - 547 IPR007685

Functions

Description
EC Number 2.7.6.5 Diphosphotransferases
Subcellular Localization
  • Plastid, chloroplast
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
chloroplast A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GTP binding Binding to GTP, guanosine triphosphate.
GTP diphosphokinase activity Catalysis of the reaction: ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate.
kinase activity Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.

2 GO annotations of biological process

Name Definition
guanosine tetraphosphate metabolic process The chemical reactions and pathways involving guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates.
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P0AG24 spoT Bifunctional (p)ppGpp synthase/hydrolase SpoT Escherichia coli (strain K12) PR
Q8N4P3 HDDC3 Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 Homo sapiens (Human) PR
Q67UU0 RSH3 Probable GTP diphosphokinase RSH3, chloroplastic Oryza sativa subsp japonica (Rice) PR
10 20 30 40 50 60
MSVPAIAVYT SPPGAVYTSS SSSELEASSR GSAPCATAAP PSPASSHRHQ AIAGGLSCLF
70 80 90 100 110 120
SSPTAAPRAA AAQDELGALW HDRSGEATAV GGGGGGGGYS YPQPSSPFKW RDMLHHSPVP
130 140 150 160 170 180
LFHSPASSPA SRSPSASWLA GRERERLFSS FVRNALGSCV DYAPVAALPL GVSAAVGVGA
190 200 210 220 230 240
GELAFELDEH LSEAEPSCEP YARDLLAGAQ ARHRIFHDEL VVKAFFEAER AHRGQTRASG
250 260 270 280 290 300
DPYLQHCVET AVLLAKIGAN ATVVSAGLLH DTIDDSFMDY DQIFRMFGAG VADLVEGVSK
310 320 330 340 350 360
LSHLSKLARD NNTASRTVEA DRLHTMFLAM ADARAVLIKL ADRLHNMKTI EALPLVKQQR
370 380 390 400 410 420
FAKETMEIFV PLANRLGIAS WKDQLENICF KHLNPEEHKE LSSKLVISFD EALLTSTLDK
430 440 450 460 470 480
LDKGLRDEGI SYHSLSGRHK SLYSIYSKMI KKNLTMDDVH DIHGLRLVVD TEQDCYQALD
490 500 510 520 530 540
IVHKLWPRVA GRFKDYILHP KLNGYRSLHT VIMCEGIHPF EVQIRTKEMH LQAEYGFAAH
550 560 570 580 590 600
WRYKEGGCKH SFVLQMVEWA RWVLTWQCEA MSKERSSGLG RSDAIRPPCP FPSHSEDCPY
610 620 630 640 650 660
SYTRQCNHDG PIFVIMLEHD KMSVQELPAN STVVDLMERV GANSPRCSPY SFPLKEELRP
670 680 690 700 710
RVNHKPISDP NRKLCMGDVV ELTPALPHKS LTEYREEIQR MYERGGFALA TTRDGPAS