Q67UU0

PR
Gene name
RSH3 (Os09g0442600, LOC_Os09g27050, P0046G12.25)
Protein name
Probable GTP diphosphokinase RSH3, chloroplastic
Names
RelA/SpoT homolog 3, OsRSH3, ppGpp synthetase RSH3
Species
Oryza sativa subsp japonica (Rice)
KEGG Pathway
osa:4347182
EC number
2.7.6.5: Diphosphotransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-180 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q67UU0

Entry ID Method Resolution Chain Position Source
AF-Q67UU0-F1 Predicted AlphaFoldDB

No variants for Q67UU0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q67UU0

No associated diseases with Q67UU0

3 regional properties for Q67UU0

Type Name Position InterPro Accession
domain HD/PDEase domain 229 - 359 IPR003607
domain HD domain 233 - 337 IPR006674
domain RelA/SpoT 415 - 537 IPR007685

Functions

Description
EC Number 2.7.6.5 Diphosphotransferases
Subcellular Localization
  • Plastid, chloroplast
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
chloroplast A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GTP binding Binding to GTP, guanosine triphosphate.
GTP diphosphokinase activity Catalysis of the reaction: ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate.
kinase activity Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.

2 GO annotations of biological process

Name Definition
guanosine tetraphosphate metabolic process The chemical reactions and pathways involving guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates.
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P0AG24 spoT Bifunctional (p)ppGpp synthase/hydrolase SpoT Escherichia coli (strain K12) PR
Q8N4P3 HDDC3 Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 Homo sapiens (Human) PR
Q7XAP4 RSH2 Probable GTP diphosphokinase RSH2, chloroplastic Oryza sativa subsp japonica (Rice) PR
10 20 30 40 50 60
MSLPAISLYT SPPPGAVYSS EFDPSSRGSS PPCSTAPPST SHRPPAAAGG LSCLFSSPAA
70 80 90 100 110 120
AASPPRAPPH DELGALWQDR SDEPAFAGGG GGYSSSPLKW RDLHHHHHHS PVSVFQGPSS
130 140 150 160 170 180
SPAASRSPPA SWLAGRDRDR ERLFAGFVRN ALGSCVDYAP ALSPRSEVGG GELAFELDEN
190 200 210 220 230 240
LAEASPACEP CARELLAGAQ ARHRIFHEEL VVKTFFEAEK AHRGQTRASG DPYLQHCVET
250 260 270 280 290 300
AVLLANIGAN STVVSAGLLH DTIDDSFIDY DHIFHMFGAG VADLVEGVSK LSHLSKLARD
310 320 330 340 350 360
NNTASRIVEA DRLHTMLLAM ADARAVLIKL ADRVHNMKTL EALPLGKQQR FAKETMEIFV
370 380 390 400 410 420
PLANRLGIAS WKDQLENLCF KHLNPEEHKD LSSKLTKSFD EVLITSAVDK LDRGLRDAGL
430 440 450 460 470 480
SYHNLSGRHK SLYSIHNKML KKNLTMDEIH DIHGLRLVFE KEEDCYRALD VVHELWPQVP
490 500 510 520 530 540
GRFKDYISRP KLNGYRSLHT VVMSENVHPF EVQIRTKEMH LQAEYGFAAH WRYKEGTCRH
550 560 570 580 590 600
SFVLQMVEWA RWVLTWQCEA MNKERPASLG DSDAIRPPCP FPMHSEDCPY SYTRQCDHDG
610 620 630 640 650 660
PIFVILLEHD KMSVQEFQAN STVMNLMDRV GTNTPRWSPY RIPMKEDLRP KVNHEPISDL
670 680 690 700
NRKLSMGDVV ELTPALPHES LPNYREEIQR MYDRGGFALA TRGGSSRR