Q6VEU1

PR
Gene name
Nob1 (Nob1p)
Protein name
RNA-binding protein NOB1
Names
Species
Rattus norvegicus (Rat)
KEGG Pathway
rno:291996
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

75-250 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6VEU1

Entry ID Method Resolution Chain Position Source
AF-Q6VEU1-F1 Predicted AlphaFoldDB

No variants for Q6VEU1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6VEU1

No associated diseases with Q6VEU1

4 regional properties for Q6VEU1

Type Name Position InterPro Accession
domain PIN domain 5 - 108 IPR002716
domain Nin one binding (NOB1) Zn-ribbon-like 258 - 330 IPR014881
domain Ribonuclease, PIN domain 7 - 109 IPR033411
domain Putative WW-binding domain and destruction box 154 - 210 IPR033461

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
preribosome, small subunit precursor A preribosomal complex consisting of 20S pre-rRNA, ribosomal proteins including late-associating small subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic small ribosomal subunit.

2 GO annotations of molecular function

Name Definition
endoribonuclease activity Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
metal ion binding Binding to a metal ion.

3 GO annotations of biological process

Name Definition
cleavage involved in rRNA processing Any phosphodiester bond hydrolysis involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule.
maturation of SSU-rRNA Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule.
visual perception The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q3T042 NOB1 RNA-binding protein NOB1 Bos taurus (Bovine) PR
Q9ULX3 NOB1 RNA-binding protein NOB1 Homo sapiens (Human) PR
Q8BW10 Nob1 RNA-binding protein NOB1 Mus musculus (Mouse) PR
10 20 30 40 50 60
MAPVEHVVAD AGAFLRDAPL QDIGKNIYTI REVVREIRDK ATRRRLAVLP YELRFKEPFP
70 80 90 100 110 120
EYVRLVTEFS KKTGDYPSLS ATDIQVLALT YQLEAEFVGV SHLKKEPEKV KVSSSIQHPE
130 140 150 160 170 180
TPLHISGFHL PSKSKALQET VDHGPPADGS ENLEFSSFMF WRNPLPNIDH ELQQLLIDGR
190 200 210 220 230 240
EEEEEEEEEE EEEDELEDSD DDGGGWITPS NIKQIQHESE QCDIPKDVQV GCVTTDFAMQ
250 260 270 280 290 300
NVLLQMGLHV LAVNGMLVRE ARSYILRCHG CFKTTSDMNR VFCGHCGNKT LKKVSVTIND
310 320 330 340 350 360
DGTLHMHFSR NPKVLNPRGL RYSLPTPKGG KYAVNPHLTE DQRFPQLRLS HKARQKTNVF
370 380 390 400
APDYIAGVSP FAENDISSRS AILQVRDSML GAGRRRLNPN ASRKKFVKKR