Q3T042

PR
Gene name
NOB1
Protein name
RNA-binding protein NOB1
Names
Species
Bos taurus (Bovine)
KEGG Pathway
bta:360191
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

75-252 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q3T042

Entry ID Method Resolution Chain Position Source
AF-Q3T042-F1 Predicted AlphaFoldDB

No variants for Q3T042

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q3T042

No associated diseases with Q3T042

4 regional properties for Q3T042

Type Name Position InterPro Accession
domain PIN domain 5 - 108 IPR002716
domain Nin one binding (NOB1) Zn-ribbon-like 261 - 333 IPR014881
domain Ribonuclease, PIN domain 7 - 109 IPR033411
domain Putative WW-binding domain and destruction box 154 - 213 IPR033461

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
preribosome, small subunit precursor A preribosomal complex consisting of 20S pre-rRNA, ribosomal proteins including late-associating small subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic small ribosomal subunit.

2 GO annotations of molecular function

Name Definition
endoribonuclease activity Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
cleavage involved in rRNA processing Any phosphodiester bond hydrolysis involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule.
maturation of SSU-rRNA Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9ULX3 NOB1 RNA-binding protein NOB1 Homo sapiens (Human) PR
Q8BW10 Nob1 RNA-binding protein NOB1 Mus musculus (Mouse) PR
Q6VEU1 Nob1 RNA-binding protein NOB1 Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MAPVEHVVAD AGAFLLDAAL QDIGKNIYTI RNVISEIRDK ATRRRLAVLP YELRFKEPFP
70 80 90 100 110 120
EYVRLVTEFS KKTGDYPSLS ATDIQVLALT YQLEAEFVGV SHLKQEPEKV KVSSSIQHPE
130 140 150 160 170 180
TPLHVSGFHL PSKPKPPRET VEHRHPASEP EDLEFSSFMF WRNPLPNIDC ELQELLMDGG
190 200 210 220 230 240
EDVPNEEEDE ENGLDERQDE DSDDDGGGWI TPSNIKQIQQ EMKQCAVPKD VRVGCVTTDF
250 260 270 280 290 300
AMQNVLLQMG LHVLAVNGML IREARSYILR CHGCFKTTSD MSRVFCAHCG NKTLKKVSVT
310 320 330 340 350 360
VSDDGTLHMH FSRNPKVLNP RGLRYSLPTP KGGKYAINPH LTEDQRFPQL RLSRKARQKT
370 380 390 400 410
DVFAPDYVAG VSPFAENDIS SRSATLQVRD STLGAGRRRL NPNASRKKFV KKR