AiPD: Autoinhibited Protein Database

Q6P1M9

Gene name	ARMCX5
Protein name	Armadillo repeat-containing X-linked protein 5
Names
Species	Homo sapiens (Human)
KEGG Pathway	hsa:64860
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-245 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

1-245 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

1 structures for Q6P1M9

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q6P1M9-F1	Predicted				AlphaFoldDB

309 variants for Q6P1M9

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
CA10475780 rs775783944	2	V>A		No	ClinGen ExAC gnomAD
rs1215236081 CA414059857	2	V>F		No	ClinGen gnomAD
TCGA novel	3	D>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA10475781 rs376521671	4	S>P		No	ClinGen ESP ExAC gnomAD
CA333914993 rs1056732662	5	G>R		No	ClinGen TOPMed
CA414059918 rs1180485038	6	T>A		No	ClinGen gnomAD
CA414059932 rs1454640404	6	T>I		No	ClinGen TOPMed
CA10475783 rs752178410	7	E>Q		No	ClinGen ExAC gnomAD
rs147081834 CA10475784	9	R>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1158005053 CA414059976	9	R>S		No	ClinGen TOPMed
TCGA novel	14	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA10475785 rs767819081	17	G>A		No	ClinGen ExAC TOPMed gnomAD
CA10475786 rs772283056	20	D>E		No	ClinGen 1000Genomes ExAC gnomAD
CA414060144 rs1199539554	22	I>V		No	ClinGen TOPMed
rs1480031482 CA414060189	24	G>S		No	ClinGen TOPMed
rs1602493664 CA414060274	30	V>M		No	ClinGen Ensembl
CA333914995 rs1017659655	36	A>S		No	ClinGen Ensembl
CA333914997 rs777165273	37	E>D		No	ClinGen TOPMed
CA10475788 rs778633013	37	E>K		No	ClinGen ExAC TOPMed gnomAD
CA333914996 rs778633013	37	E>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1486111547 CA414060499	42	A>V		No	ClinGen TOPMed
CA10475789 rs747742515	45	K>R		No	ClinGen ExAC TOPMed gnomAD
CA414060633 rs1317140536	50	T>A		No	ClinGen gnomAD
CA10475790 rs757964410	50	T>I		No	ClinGen ExAC
TCGA novel	52	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1307008813 CA414060738	55	G>C		No	ClinGen gnomAD
CA414060746 rs1318370282	55	G>V		No	ClinGen gnomAD
rs746990723 CA10475792	57	G>R		No	ClinGen ExAC TOPMed gnomAD
CA10475793 rs770882008	58	A>V		No	ClinGen ExAC gnomAD
rs976516077 CA333914999	64	T>A		No	ClinGen gnomAD
rs1314190529 CA414060909	64	T>R		No	ClinGen TOPMed
CA10475797 rs775908725	67	Y>C		No	ClinGen ExAC gnomAD
rs763262040 CA10475798	71	M>L		No	ClinGen ExAC gnomAD
rs1413251452 CA414061055	72	A>P		No	ClinGen gnomAD
rs923526734 CA333915000	74	T>R		No	ClinGen TOPMed
CA10475799 rs764309369	75	R>S		No	ClinGen ExAC gnomAD
rs761752157 CA10475801	81	E>K		No	ClinGen ExAC TOPMed gnomAD
CA333915001 rs951073931	82	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
TCGA novel	83	T>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA414061247 rs1287902867	83	T>R		No	ClinGen TOPMed
rs138502487 CA10475802	84	T>I		No	ClinGen ESP ExAC gnomAD
CA414061283 rs1398036389	85	K>N		No	ClinGen gnomAD
rs1429627218 CA414061304	87	R>G		No	ClinGen gnomAD
rs1298666212 CA414061345	89	M>V		No	ClinGen gnomAD
CA333915002 rs942177128	91	E>D		No	ClinGen gnomAD
CA10475805 rs766719928	94	T>A		No	ClinGen ExAC gnomAD
CA10475806 rs752417086	95	K>E		No	ClinGen ExAC TOPMed gnomAD
CA414061476 rs1427105317	96	P>A		No	ClinGen TOPMed
CA10475807 rs758017459	96	P>L		No	ClinGen ExAC gnomAD
CA414061477 rs1427105317	96	P>S		No	ClinGen TOPMed
rs1428870286 CA414061499	97	L>P		No	ClinGen TOPMed
CA10475808 rs777317204	98	A>V		No	ClinGen ExAC gnomAD
rs12013441 CA10475809	100	R>C		No	ClinGen ExAC TOPMed gnomAD
CA10475810 rs112989637	100	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA414061564 rs112989637	100	R>P		No	ClinGen ESP ExAC TOPMed gnomAD
rs1569479954 CA414061572	101	S>G		No	ClinGen Ensembl
rs781198467 CA10475811	101	S>N		No	ClinGen ExAC TOPMed gnomAD
CA10475812 rs374726828	102	I>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA414061617 rs1321585422	105	Q>E		No	ClinGen TOPMed
CA414061616 rs1321585422	105	Q>K		No	ClinGen TOPMed
TCGA novel	107	K>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA333915003 rs1009936608	107	K>E		No	ClinGen TOPMed
TCGA novel	108	S>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs749568583 CA10475815	108	S>P		No	ClinGen ExAC gnomAD
CA10475816 rs769019967	109	K>R		No	ClinGen ExAC gnomAD
CA10475818 rs761960075 CA10475819	111	M>I		No	ClinGen ExAC gnomAD
CA10475817 rs760692111	111	M>V		No	ClinGen 1000Genomes ExAC gnomAD
rs1293831831 CA414061751	112	P>A		No	ClinGen TOPMed
CA414061795 rs773828294	114	S>A		No	ClinGen ExAC TOPMed gnomAD
rs1213364116 CA414061796	114	S>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs773828294 CA10475820	114	S>P		No	ClinGen ExAC TOPMed gnomAD
rs112318694 CA333915005	117	S>G		No	ClinGen Ensembl
rs41307379 CA333915006	119	V>L		No	ClinGen Ensembl
rs766774856 CA10475822	121	K>N		No	ClinGen ExAC TOPMed gnomAD
rs1299403011 CA414061944	123	E>G		No	ClinGen TOPMed
CA414061969 rs1345766890	125	K>E		No	ClinGen gnomAD
CA10475823 rs764283175	125	K>T		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1275903870 CA414061983	126	V>I		No	ClinGen gnomAD
TCGA novel	131	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	132	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs759848417 CA10475824	134	I>V		No	ClinGen ExAC TOPMed gnomAD
CA10475825 rs763738026	135	R>M		No	ClinGen ExAC TOPMed gnomAD
rs751112777 CA10475826	135	R>S		No	ClinGen ExAC TOPMed gnomAD
rs1000666618 CA333915008	137	Y>F		No	ClinGen Ensembl
CA10475827 CA414062231 rs776569480	142	D>E		No	ClinGen 1000Genomes ExAC gnomAD
rs780559667 CA10475828	147	G>V		No	ClinGen ExAC gnomAD
rs750414266 CA10475829	150	P>S		No	ClinGen ExAC gnomAD
CA333915009 rs756099007	151	D>E		No	ClinGen ExAC gnomAD
rs1194546099 CA414062387	152	R>G		No	ClinGen gnomAD
CA414062446 rs1186847886	155	E>*		No	ClinGen gnomAD
rs35450554 CA10475832	156	T>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA333915010 rs997524032	157	S>I		No	ClinGen gnomAD
CA414062478 rs997524032	157	S>N		No	ClinGen gnomAD
CA333915011 rs369047406	158	I>F		No	ClinGen ESP ExAC TOPMed gnomAD
rs1365727293 CA414062500	158	I>T		No	ClinGen TOPMed gnomAD
rs369047406 CA10475833	158	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA333915012 rs923659718	162	S>F		No	ClinGen TOPMed gnomAD
TCGA novel	162	S>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs201641747 CA10475835	163	S>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA10475836 rs772263868	165	E>G		No	ClinGen ExAC gnomAD
TCGA novel	166	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA10475837 rs773138492	167	E>K		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	169	N>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1272227101 CA414062766	169	N>T		No	ClinGen gnomAD
CA10475838 rs375887903	170	I>L		No	ClinGen ESP ExAC gnomAD
CA414062781 rs1315280518	170	I>T		No	ClinGen TOPMed
CA10475839 rs375887903	170	I>V		No	ClinGen ESP ExAC gnomAD
rs763159758 CA333915013	173	W>R		No	ClinGen Ensembl
TCGA novel	174	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA10475840 rs777053533	176	T>A		No	ClinGen ExAC TOPMed gnomAD
rs765569290 CA10475842	182	V>A		No	ClinGen ExAC
rs1283860891 CA414063039	185	W>G		No	ClinGen gnomAD
TCGA novel	187	W>C	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs935033680 CA333915015	190	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA414063149 rs1447730376	190	E>K		No	ClinGen gnomAD
CA10475843 rs751288317	191	E>D		No	ClinGen ExAC gnomAD
CA10475845 rs767103137	193	S>F		No	ClinGen ExAC
CA10475846 rs749922493	194	L>F		No	ClinGen ExAC gnomAD
CA10475847 rs755643991	194	L>P		No	ClinGen ExAC
rs370774795 CA10475849	197	Y>C		No	ClinGen ESP ExAC TOPMed gnomAD
rs1385758542 CA414063280	197	Y>H		No	ClinGen gnomAD
rs1426285800 CA414063427	205	E>G		No	ClinGen TOPMed
CA10475851 rs758798400	206	K>E		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1452335292 CA414063508	209	P>H		No	ClinGen gnomAD
rs767302829 CA10475852	209	P>S		No	ClinGen 1000Genomes ExAC gnomAD
rs758529861 CA10475853	211	H>Q		No	ClinGen ExAC gnomAD
rs1400172327 CA414063564	212	K>R		No	ClinGen TOPMed gnomAD
CA10475854 rs778007632	213	P>A		No	ClinGen ExAC gnomAD
rs1238059817 CA414063588	214	T>A		No	ClinGen TOPMed gnomAD
CA333915016 rs963511931	217	I>V		No	ClinGen Ensembl
CA10475855 rs747125732	218	K>Q		No	ClinGen ExAC gnomAD
TCGA novel	221	V>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA414063707 rs1365763904	221	V>G		No	ClinGen TOPMed
rs1328810386 CA414063730	222	I>T		No	ClinGen gnomAD
CA414063738 rs1182601370	223	A>T		No	ClinGen TOPMed
rs770936094 CA10475856	225	S>L		No	ClinGen ExAC TOPMed gnomAD
CA333915017 rs980295564	226	R>G		No	ClinGen Ensembl
TCGA novel	227	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1248994212 CA414063822	228	R>G		No	ClinGen TOPMed
CA10475858 rs746367535	229	Y>C		No	ClinGen ExAC
CA414063844 rs1276724162	229	Y>H		No	ClinGen gnomAD
rs373013040 CA10475859	230	I>T		No	ClinGen ESP ExAC TOPMed gnomAD
TCGA novel	231	V>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs755694549 CA10475860	237	G>A		No	ClinGen 1000Genomes ExAC gnomAD
rs1490662118 CA414063975	237	G>R		No	ClinGen TOPMed
TCGA novel	238	G>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA10475861 rs763326554	238	G>R		No	ClinGen ExAC TOPMed gnomAD
CA10475863 rs772853746	239	E>G		No	ClinGen ExAC gnomAD
CA10475862 rs767105830	239	E>K		No	ClinGen ExAC
CA10475864 rs139851001	243	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
rs948341958 CA333915018	244	P>L		No	ClinGen TOPMed
CA333915019 rs866578212	246	G>E		No	ClinGen Ensembl
rs1362774825 CA414064120	246	G>R		No	ClinGen gnomAD
rs765976307 CA10475865	248	W>C		No	ClinGen ExAC TOPMed gnomAD
CA333915020 rs377411016	249	T>I		No	ClinGen ESP TOPMed gnomAD
rs753895997 CA333915021	250	L>M		No	ClinGen ExAC gnomAD
CA10475867 rs754938559	251	V>F		No	ClinGen ExAC gnomAD
CA333915022 rs375842205	252	E>K		No	ClinGen Ensembl
CA10475868 rs765132384	253	T>I		No	ClinGen ExAC gnomAD
TCGA novel	258	P>missing	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs777867447 CA10475871	262	R>*		No	ClinGen ExAC gnomAD
rs1056127986 CA333915024	262	R>Q		No	ClinGen Ensembl
rs1444433505 CA414064467	266	K>M		No	ClinGen gnomAD
CA10475873 rs143305512	267	I>F		No	ClinGen ESP ExAC TOPMed gnomAD
rs1323042694 CA414064531	269	P>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs139067925 CA10475876	277	T>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA10475879 rs749617854	283	K>N		No	ClinGen ExAC gnomAD
rs749534706	283	K>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	NCI-TCGA
rs769008473 CA10475880	285	I>M		No	ClinGen ExAC TOPMed gnomAD
CA414064836 rs1159404940	285	I>V		No	ClinGen TOPMed
CA414064962 rs1266371628	291	Y>C		No	ClinGen gnomAD
CA10475881 rs772797845	291	Y>H		No	ClinGen ExAC gnomAD
CA414065004 rs1176689378	294	N>D		No	ClinGen gnomAD
CA10475884 rs376270648	295	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA10475883 rs376270648	295	P>Q		No	ClinGen ESP ExAC TOPMed gnomAD
rs887148982 CA333915026	295	P>S		No	ClinGen TOPMed
CA414065093 rs1167891788	299	H>D		No	ClinGen gnomAD
rs765121989 CA10475886 COSM305503	299	H>R	central_nervous_system [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
rs1393244084 CA414065152	302	S>P		No	ClinGen TOPMed gnomAD
TCGA novel	302	S>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs759494842 CA10475887	303	R>C		No	ClinGen ExAC TOPMed gnomAD
CA414065165 rs759494842	303	R>G		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	304	G>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs377359903 CA10475888	306	S>N		No	ClinGen ESP ExAC TOPMed gnomAD
rs1349534818 CA414065294	309	P>L		No	ClinGen TOPMed
rs1201063133 CA414065286	309	P>S		No	ClinGen TOPMed gnomAD
rs113918916 CA333915027	311	E>G		No	ClinGen Ensembl
CA414065425 rs1285429216	316	V>A		No	ClinGen gnomAD
TCGA novel	318	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	319	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1224825577 CA414065535	321	L>F		No	ClinGen TOPMed
rs1602495118 CA414065640	328	H>N		No	ClinGen Ensembl
TCGA novel	328	H>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	329	E>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	329	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA414065716 rs1347211430	331	A>G		No	ClinGen TOPMed gnomAD
rs370182133 CA10475890	333	M>T		No	ClinGen ESP ExAC TOPMed
CA333915028 rs868738831	336	G>D		No	ClinGen Ensembl
rs1019659336 CA333915029	337	I>V		No	ClinGen TOPMed
TCGA novel	342	P>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1339951743 CA414065961	345	Q>*		No	ClinGen gnomAD
CA414065972 rs1381821045	345	Q>P		No	ClinGen TOPMed
TCGA novel	347	I>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA10475893 rs750531280	347	I>V		No	ClinGen ExAC gnomAD
CA10475894 rs756152594	349	H>L		No	ClinGen ExAC TOPMed gnomAD
CA333915030 rs866416226	349	H>Y		No	ClinGen Ensembl
rs1178601130 CA414066068	350	D>G		No	ClinGen TOPMed
rs1429198188 CA414066136	354	T>I		No	ClinGen TOPMed
rs1199746561 CA414066157	355	V>A		No	ClinGen gnomAD
rs1476582628 CA414066175	356	M>T		No	ClinGen TOPMed
CA333915031 rs1000634112	356	M>V		No	ClinGen TOPMed gnomAD
TCGA novel	359	N>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1038880909 CA333915032	360	L>F		No	ClinGen Ensembl
CA10475896 rs749789460	361	V>I		No	ClinGen ExAC TOPMed gnomAD
rs768968357 CA10475897	362	N>S		No	ClinGen ExAC gnomAD
rs767404642 CA10475898	364	P>L		No	ClinGen ExAC TOPMed gnomAD
CA10475899 rs746711877	365	N>S		No	ClinGen ExAC gnomAD
rs1245831353 CA414067307	368	E>Q		No	ClinGen TOPMed
CA414067339 rs1382487281	369	H>Q		No	ClinGen TOPMed gnomAD
CA414067381 rs1569480308	372	A>D		No	ClinGen Ensembl
CA414067401 rs1162212868	374	S>G		No	ClinGen gnomAD
rs770732927 CA10475900	375	M>V		No	ClinGen ExAC TOPMed gnomAD
rs200145435 CA10475902	378	D>E		No	ClinGen ExAC TOPMed gnomAD
rs1383003699 CA414067521	379	S>N		No	ClinGen gnomAD
TCGA novel	379	S>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs752535299 CA333915033	381	E>D		No	ClinGen Ensembl
rs762914687 CA10475905	384	E>K	Variant assessed as Somatic; 0.0002501 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs763841626 CA10475906	386	P>T		No	ClinGen ExAC TOPMed gnomAD
rs761553267 CA10475908	387	K>Q		No	ClinGen ExAC gnomAD
rs1363267282 CA414067697	390	E>*		No	ClinGen TOPMed
rs149355875 CA10475911	390	E>D		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1363267282 CA414067695	390	E>Q		No	ClinGen TOPMed
CA10475912 rs780177987	391	S>P		No	ClinGen ExAC gnomAD
CA414067836 rs1262944287	397	C>S		No	ClinGen TOPMed gnomAD
CA414067847 rs1602495480	397	C>Y		No	ClinGen Ensembl
CA10475915 rs779517538	398	K>R		No	ClinGen ExAC TOPMed gnomAD
rs991863102 CA333915034	403	C>R		No	ClinGen TOPMed
rs1445344175 CA414068076	408	P>T		No	ClinGen gnomAD
CA10475917 rs142617709	409	V>G		No	ClinGen ESP ExAC gnomAD
CA414068132 rs1387903043	411	L>V		No	ClinGen TOPMed
rs781008940 CA10475919	413	G>A		No	ClinGen ExAC TOPMed gnomAD
rs781008940 CA10475918	413	G>E		No	ClinGen ExAC TOPMed gnomAD
CA414068306 rs1385448235	422	I>V		No	ClinGen gnomAD
CA414068322 rs1436974827	423	K>T		No	ClinGen gnomAD
CA333915035 rs1034553174	425	E>G		No	ClinGen Ensembl
rs960246032 CA333915036	426	D>H		No	ClinGen Ensembl
CA10475921 rs775040513	427	H>Y		No	ClinGen ExAC gnomAD
rs1241941436 CA414068498	434	I>T		No	ClinGen TOPMed
rs762318478 CA10475922	434	I>V		No	ClinGen ExAC gnomAD
CA414068506 rs1314602059	436	D>N		No	ClinGen gnomAD
TCGA novel	438	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1207416009 CA414068662	443	K>N		No	ClinGen TOPMed
rs992281117 CA333915037	443	K>T		No	ClinGen Ensembl
rs761610220 CA10475925	445	S>N		No	ClinGen ExAC gnomAD
rs201473675 CA10475927	450	F>L		No	ClinGen ExAC TOPMed gnomAD
rs760920872 CA10475928	452	V>A		No	ClinGen ExAC gnomAD
CA414068860 rs186882890	455	V>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA10475929 rs186882890	455	V>M		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1405965221 CA414068885	457	S>*		No	ClinGen TOPMed gnomAD
rs1405965221 CA414068889 COSM3843053	457	S>L	Variant assessed as Somatic; impact. breast [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
TCGA novel	457	S>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs765848046 CA10475932	458	C>Y		No	ClinGen ExAC gnomAD
COSM456369 CA10475933 rs753200471	463	H>Q	Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD
CA333915038 rs140890801	463	H>R		No	ClinGen ESP TOPMed
CA414068964 rs1458646609	464	A>G		No	ClinGen gnomAD
rs947710517 CA333915039	464	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
TCGA novel	467	R>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs758896663 CA10475934	467	R>T		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	470	I>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs753433648 CA333915041	473	K>R		No	ClinGen TOPMed
rs1367794687 CA414069084	477	S>*		No	ClinGen TOPMed
rs1164642994 CA414069102	479	V>I		No	ClinGen TOPMed
TCGA novel	480	A>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs756875554 CA333915042	483	N>K		No	ClinGen TOPMed
rs755810411 CA10475937	486	E>Q		No	ClinGen ExAC TOPMed gnomAD
rs778307769 CA333915044	489	A>G		No	ClinGen Ensembl
TCGA novel	489	A>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA414069229 rs1390291216	490	N>Y		No	ClinGen gnomAD
CA10475938 rs779531158	495	I>V		No	ClinGen ExAC gnomAD
CA414069294 rs1290614480	496	E>A		No	ClinGen gnomAD
TCGA novel	499	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	500	N>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA414069416 rs1233357976	505	F>I		No	ClinGen TOPMed
rs748834056 CA10475939	508	K>Q		No	ClinGen ExAC gnomAD
rs774329171 CA10475941	509	A>S		No	ClinGen ExAC TOPMed gnomAD
rs774329171 CA414069465	509	A>T		No	ClinGen ExAC TOPMed gnomAD
CA414069511 rs1293626733	513	T>N		No	ClinGen TOPMed
CA10475944 rs773039042	518	T>A		No	ClinGen ExAC TOPMed gnomAD
CA414069567 rs773039042	518	T>S		No	ClinGen ExAC TOPMed gnomAD
rs1358925759 CA414069573	519	K>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs367941873 CA10475945	519	K>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA333915045 rs887273515	523	I>T		No	ClinGen TOPMed
CA333915046 rs539090958	525	I>V		No	ClinGen gnomAD
CA10475946 rs200184974	527	Q>E		No	ClinGen ESP ExAC TOPMed gnomAD
CA10475947 rs776653260	527	Q>R		No	ClinGen ExAC gnomAD
CA10475948 rs759705815	529	A>T		No	ClinGen ExAC gnomAD
CA10475949 rs769324479	531	Q>R		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	534	Q>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA10475951 rs775244048	540	A>V		No	ClinGen 1000Genomes ExAC gnomAD
rs1351966633 CA414069879	546	E>A		No	ClinGen gnomAD
CA414069877 rs1298188206 COSM1112108	546	E>K	Variant assessed as Somatic; 0.0 impact. pancreas endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA gnomAD
rs1402782902 CA414069899	548	R>K		No	ClinGen gnomAD
CA333915048 rs899863542	549	D>E		No	ClinGen TOPMed
TCGA novel	549	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA333915049 rs933186129	552	I>M		No	ClinGen TOPMed
COSM293359 rs1366416541 CA414069954	553	R>*	large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
CA10475954 rs757494690	555	I>V		No	ClinGen ExAC TOPMed
TCGA novel	557	K>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA414070036 rs1408018339	559	L>C		No	ClinGen TOPMed

No associated diseases with Q6P1M9

No regional properties for Q6P1M9

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for Q6P1M9

Functions

		Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

No GO annotations of cellular component

Name	Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name	Definition
No GO annotations for molecular function

No GO annotations of biological process

Name	Definition
No GO annotations for biological process

4 homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q9UH62	ARMCX3	Armadillo repeat-containing X-linked protein 3	Homo sapiens (Human)	PR
Q5U4C1	Gprasp1	G-protein coupled receptor-associated sorting protein 1	Mus musculus (Mouse)	PR
Q8BUY8	Gprasp2	G-protein coupled receptor-associated sorting protein 2	Mus musculus (Mouse)	PR
Q3UZB0	Armcx5	Armadillo repeat-containing X-linked protein 5	Mus musculus (Mouse)	PR

10	20	30	40	50	60
MVDSGTEARA	RGKAEAGLQD	GISGPATARV	NGKTQAEAVA	EAELKTESVT	QAKAGDGAMT
70	80	90	100	110	120
RTHTVTYREA	MAVTREVIKV	EDTTKTRVMV	ETKTKPLAER	SIVPQTKSKA	MPMSRVSTVT
130	140	150	160	170	180
KSEVKVVAVI	EANIRSYAKS	HDKANTGSRP	DRREETSIGM	KSSDEDEENI	CSWFWTGEEP
190	200	210	220	230	240
SVGSWFWPEE	ETSLQVYKPL	PKIQEKPKPT	HKPTLTIKQK	VIAWSRARYI	VLVPVEGGEQ
250	260	270	280	290	300
SLPPEGNWTL	VETLIETPLG	IRPLTKIPPY	HGPYYQTLAE	IKKQIRQREK	YGPNPKACHC
310	320	330	340	350	360
KSRGFSLEPK	EFDKLVALLK	LTKDPFIHEI	ATMIMGISPA	YPFTQDIIHD	VGITVMIENL
370	380	390	400	410	420
VNNPNVKEHP	GALSMVDDSS	ESSEEPKSGE	SYIHQVCKGI	ISCPLNSPVQ	LAGLKLLGHL
430	440	450	460	470	480
SIKFEDHYVI	TSYIPDFLTL	LNKGSVKTKF	YVLKVFSCLS	KNHANTRELI	SAKVLSSLVA
490	500	510	520	530	540
PFNKNESKAN	ILNIIEIFEN	INFQFKTKAK	LFTKEKFTKS	ELISIFQEAK	QFGQKLQDLA
550
EHSDPEVRDK	VIRLILKL