Q6GVM3

PR
Gene name
EIF1AY
Protein name
Eukaryotic translation initiation factor 1A, Y-chromosomal
Names
eIF-1A Y isoform, Eukaryotic translation initiation factor 4C, eIF-4C
Species
Pan troglodytes (Chimpanzee)
KEGG Pathway
ptr:449499
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-55 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6GVM3

Entry ID Method Resolution Chain Position Source
AF-Q6GVM3-F1 Predicted AlphaFoldDB

No variants for Q6GVM3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6GVM3

No associated diseases with Q6GVM3

1 regional properties for Q6GVM3

Type Name Position InterPro Accession
domain EF-hand domain 434 - 469 IPR002048

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

1 GO annotations of biological process

Name Definition
translational initiation The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P47813 EIF1AX Eukaryotic translation initiation factor 1A, X-chromosomal Homo sapiens (Human) PR
O14602 EIF1AY Eukaryotic translation initiation factor 1A, Y-chromosomal Homo sapiens (Human) PR
Q8BMJ3 Eif1ax Eukaryotic translation initiation factor 1A, X-chromosomal Mus musculus (Mouse) PR
10 20 30 40 50 60
MPKNKGKGGK NRRRGKNENE SEKRELVFKE DGQEYAQVIK MLGNGRLEAL CFDGVKRLCH
70 80 90 100 110 120
IRGKLRKKVW INTSDIILVG LRDYQDNKAD VILKYNADEA RSLKAYGELP EHAKINETDT
130 140
FGPGDDDEVQ FDDIGDDDED IDDI