Q6AXM1

PR
Gene name
chst10 (zgc:100964)
Protein name
Carbohydrate sulfotransferase 10
Names
HNK-1 sulfotransferase, HNK-1ST, HNK1ST
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
KEGG Pathway
dre:445322
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

32-108 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q6AXM1

Entry ID Method Resolution Chain Position Source
AF-Q6AXM1-F1 Predicted AlphaFoldDB

No variants for Q6AXM1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q6AXM1

No associated diseases with Q6AXM1

No regional properties for Q6AXM1

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q6AXM1

Functions

Description
EC Number
Subcellular Localization
  • Golgi apparatus membrane ; Single-pass type II membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
sulfotransferase activity Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyl group of an acceptor, producing the sulfated derivative and 3'-phosphoadenosine 5'-phosphate.

2 GO annotations of biological process

Name Definition
carbohydrate biosynthetic process The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
proteoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
O43529 CHST10 Carbohydrate sulfotransferase 10 Homo sapiens (Human) PR
Q6PGK7 Chst10 Carbohydrate sulfotransferase 10 Mus musculus (Mouse) PR
O54702 Chst10 Carbohydrate sulfotransferase 10 Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MRRHWLLVGA CGWVLLILMF VSKFINFSFR IPGDYAGRSE IFVWTLSSVT TKLPSVVWPE
70 80 90 100 110 120
KGASQPYILS SVSPSVVEPI DWHLVNEKRL EQLSTVCSNS SIWNLTHTTV RKFVLDRIFV
130 140 150 160 170 180
CDKHKILFCQ TPKVGNTQWK KVLIVLNGKF SKVEAIPENL VHDHERNGLP RLSSMTDTEI
190 200 210 220 230 240
HQRLNSYFKF FIVRDPFERL ISAFKDKFVK NPRFEPWYKH DIAPAIVRKY RRSHHDDSES
250 260 270 280 290 300
VGLRFEDFVR YLGDKTGRQH LDRQFGDHII HWLTYAELCA PCDISYNVVG HHETLELDAP
310 320 330 340 350 360
YILKSAGIAG LVSYPSIPPG ITRYNRTKVE RYFSGISQRD IRRLYARYQG DFSLFDYPKP
AFLLN