O54702
Gene name |
Chst10 |
Protein name |
Carbohydrate sulfotransferase 10 |
Names |
HNK-1 sulfotransferase, HNK-1ST, HNK1ST, RaHNK-1ST, Sul-T |
Species |
Rattus norvegicus (Rat) |
KEGG Pathway |
rno:140568 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O54702
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O54702-F1 | Predicted | AlphaFoldDB |
No variants for O54702
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O54702 | |||||
No associated diseases with O54702
No regional properties for O54702
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O54702 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| HNK-1 sulfotransferase activity | Catalysis of the synthesis of the HKK-1 carbohydrate epitope; adds a sulfate group to a precursor, GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R), forming sulfo-3GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R). |
| sulfotransferase activity | Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyl group of an acceptor, producing the sulfated derivative and 3'-phosphoadenosine 5'-phosphate. |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| androgen metabolic process | The chemical reactions and pathways involving androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics. |
| carbohydrate biosynthetic process | The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. |
| estrogen metabolic process | The chemical reactions and pathways involving estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants. |
| learning | Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience. |
| long-term memory | The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation. |
| proteoglycan biosynthetic process | The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. |
3 homologous proteins in AiPD
| 10 | 20 | 30 | 40 | 50 | 60 |
| MHHQWLLLAA | CFWVIFMFMV | ASKFITLTFK | DPDGYSAKQE | FVFLTAMPEA | EKLRGEKHFS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EVMKPTGKML | SESHPDQPPV | YLERLELIRN | ACKEEALRNL | SHTEVSKFVL | DRIFVCDKHK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ILFCQTPKVG | NTQWKKVLIV | LNGAFSSIEE | IPENVVHDHE | KNGLPRLSSF | SKIGIQKRLK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TYFKFFIVRD | PFERLISAFK | DKFVHNPRFE | PWYRHEIAPG | IIRKYRKNRT | ETRGIQFEDF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VRYLGDPNRR | WLDLQFGDHI | IHWVTYVKLC | APCEIKYSVI | GHHETLEADA | PYILKEAGID |
| 310 | 320 | 330 | 340 | 350 | |
| HLVSYPTIPP | GITMYNRTKV | EQYFLGISKR | DIRRLYARFE | GDFKLFGYQK | PDFLLN |