Q5PP28
PR
Gene name |
NAC003 (At1g02220, T7I23.18) |
Protein name |
NAC domain-containing protein 3 |
Names |
ANAC003 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G02220 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5PP28
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5PP28-F1 | Predicted | AlphaFoldDB |
74 variants for Q5PP28
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH01004361 | 3 | T>N | No | 1000Genomes | |
| ENSVATH01004359 | 14 | E>K | No | 1000Genomes | |
| ENSVATH01004356 | 22 | W>R | No | 1000Genomes | |
| ENSVATH00002169 | 27 | D>V | No | 1000Genomes | |
| ENSVATH00002167 | 36 | F>V | No | 1000Genomes | |
| ENSVATH01004354 | 41 | P>T | No | 1000Genomes | |
| ENSVATH01004353 | 42 | V>I | No | 1000Genomes | |
| ENSVATH01004352 | 44 | R>K | No | 1000Genomes | |
| ENSVATH01004351 | 45 | L>F | No | 1000Genomes | |
| ENSVATH01004351 | 45 | L>I | No | 1000Genomes | |
| ENSVATH01004341 | 61 | V>E | No | 1000Genomes | |
| ENSVATH01004340 | 62 | A>T | No | 1000Genomes | |
| ENSVATH01004339 | 67 | R>S | No | 1000Genomes | |
| ENSVATH01004337 | 80 | M>I | No | 1000Genomes | |
| ENSVATH01004336 | 90 | S>I | No | 1000Genomes | |
| ENSVATH01004334 | 93 | R>K | No | 1000Genomes | |
| ENSVATH04506543 | 95 | K>T | No | 1000Genomes | |
| ENSVATH04506542 | 96 | P>R | No | 1000Genomes | |
| ENSVATH00002163 | 103 | Q>K | No | 1000Genomes | |
| ENSVATH01004333 | 103 | Q>P | No | 1000Genomes | |
| ENSVATH04506541 | 104 | I>F | No | 1000Genomes | |
| ENSVATH04506540 | 104 | I>M | No | 1000Genomes | |
| tmp_1_430148_T_A | 108 | K>M | No | 1000Genomes | |
| ENSVATH01004332 | 114 | T>K | No | 1000Genomes | |
| ENSVATH00002162 | 129 | G>V | No | 1000Genomes | |
| ENSVATH00002161 | 132 | H>P | No | 1000Genomes | |
| ENSVATH04506539 | 135 | M>L | No | 1000Genomes | |
| ENSVATH01004326 | 138 | T>R | No | 1000Genomes | |
| ENSVATH04506538 | 138 | T>S | No | 1000Genomes | |
| tmp_1_429983_G_C | 139 | Y>* | No | 1000Genomes | |
| ENSVATH04506537 | 144 | V>L | No | 1000Genomes | |
| tmp_1_429967_T_G | 145 | M>L | No | 1000Genomes | |
| tmp_1_429963_A_C | 146 | F>C | No | 1000Genomes | |
| ENSVATH01004324 | 147 | N>K | No | 1000Genomes | |
| ENSVATH01004323 | 150 | M>V | No | 1000Genomes | |
| ENSVATH01004322 | 155 | S>F | No | 1000Genomes | |
| tmp_1_429916_C_T | 162 | G>S | No | 1000Genomes | |
| ENSVATH04506536 | 168 | Q>H | No | 1000Genomes | |
| tmp_1_429895_T_C | 169 | S>G | No | 1000Genomes | |
| ENSVATH04506535 | 170 | R>H | No | 1000Genomes | |
| tmp_1_429874_G_A | 176 | P>S | No | 1000Genomes | |
| ENSVATH01004321 | 177 | Q>H | No | 1000Genomes | |
| ENSVATH04506532 | 193 | S>C | No | 1000Genomes | |
| ENSVATH00002159 | 199 | L>Q | No | 1000Genomes | |
| tmp_1_429726_T_G | 200 | Q>H | No | 1000Genomes | |
| tmp_1_429716_T_C | 204 | I>V | No | 1000Genomes | |
| ENSVATH00002158 | 208 | K>I | No | 1000Genomes | |
| ENSVATH00002158 | 208 | K>R | No | 1000Genomes | |
| ENSVATH10462298 | 215 | K>N | No | 1000Genomes | |
| ENSVATH04506531 | 220 | D>N | No | 1000Genomes | |
| ENSVATH04506531 | 220 | D>Y | No | 1000Genomes | |
| ENSVATH04506530 | 224 | A>T | No | 1000Genomes | |
| ENSVATH01004312 | 236 | E>K | No | 1000Genomes | |
| ENSVATH01004311 | 245 | A>S | No | 1000Genomes | |
| ENSVATH01004310 | 252 | F>S | No | 1000Genomes | |
| ENSVATH01004309 | 253 | M>L | No | 1000Genomes | |
| tmp_1_429518_A_T | 270 | F>I | No | 1000Genomes | |
| tmp_1_429510_A_T | 272 | D>E | No | 1000Genomes | |
| ENSVATH00002157 | 274 | V>D | No | 1000Genomes | |
| ENSVATH01004308 | 276 | S>N | No | 1000Genomes | |
| tmp_1_429330_C_T | 302 | S>N | No | 1000Genomes | |
| tmp_1_429322_G_C | 305 | H>D | No | 1000Genomes | |
| ENSVATH01004297 | 333 | A>V | No | 1000Genomes | |
| tmp_1_429074_A_G | 338 | I>T | No | 1000Genomes | |
| tmp_1_429075_T_C | 338 | I>V | No | 1000Genomes | |
| ENSVATH01004293 | 341 | A>S | No | 1000Genomes | |
| ENSVATH07500807 | 343 | K>N | No | 1000Genomes | |
| ENSVATH07500806 | 344 | K>E | No | 1000Genomes | |
| ENSVATH07500805 | 344 | K>N | No | 1000Genomes | |
| ENSVATH10462167 | 347 | P>A | No | 1000Genomes | |
| ENSVATH01004292 | 349 | D>G | No | 1000Genomes | |
| ENSVATH01004291 | 350 | D>G | No | 1000Genomes | |
| ENSVATH01004288 | 368 | K>N | No | 1000Genomes | |
| tmp_1_428955_T_G | 378 | I>L | No | 1000Genomes |
No associated diseases with Q5PP28
1 regional properties for Q5PP28
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Mad3/Bub1 homology region 1 | 55 - 226 | IPR013212 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA-binding transcription factor activity | A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. |
| transcription cis-regulatory region binding | Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9M274 | NAC066 | NAC domain-containing protein 66 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q84WP6 | NAC043 | NAC domain-containing protein 43 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9C878 | BRN1 | Protein BEARSKIN1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FWX2 | NAC007 | NAC domain-containing protein 7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| F4JN35 | NTL9 | Protein NTM1-like 9 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| METPVGLRFC | PTDEEIVVDY | LWPKNSDRDT | SHVDRFINTV | PVCRLDPWEL | PCQSRIKLKD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VAWCFFRPKE | NKYGRGDQQM | RKTKSGFWKS | TGRPKPIMRN | RQQIGEKKIL | MFYTSKESKS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DWVIHEYHGF | SHNQMMMTYT | LCKVMFNGGM | REKSSSSPSS | SGVSGIEQSR | RDSLIPQLVN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NSEGSSLHRE | DPSQFGDVLQ | EAPIEDAKLT | EELVKWLMND | EDDAQIEDAI | PIEEWETWLN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DIDDAKEKSI | MFMHDNRSDY | RPPNSLTGVF | SDDVSSDDND | SDLLTPKTNS | IQTSSTCDSF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GSSNHRIDQI | KDLQESPTST | INLVSLTQEV | SQALITSIDT | AEKKKNPYDD | AQGTEIGEHK |
| 370 | 380 | 390 | |||
| LGQETIKKKR | AGFFHRMIQK | FVKKIHLCSS | ISRT |