F4JN35
PR
Gene name |
NTL9 |
Protein name |
Protein NTM1-like 9 |
Names |
Calmodulin-binding NAC protein |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT4G35580 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for F4JN35
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-F4JN35-F1 | Predicted | AlphaFoldDB |
50 variants for F4JN35
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH12412183 | 3 | A>T | No | 1000Genomes | |
| ENSVATH14341412 | 18 | T>I | No | 1000Genomes | |
| tmp_4_16890603_T_G | 48 | K>Q | No | 1000Genomes | |
| tmp_4_16890457_A_G | 57 | L>P | No | 1000Genomes | |
| ENSVATH06829893 | 59 | V>M | No | 1000Genomes | |
| ENSVATH06829892 | 75 | R>W | No | 1000Genomes | |
| ENSVATH06829890 | 147 | G>S | No | 1000Genomes | |
| ENSVATH00553828 | 164 | V>A | No | 1000Genomes | |
| tmp_4_16890137_C_T | 164 | V>I | No | 1000Genomes | |
| tmp_4_16890062_G_C | 189 | L>V | No | 1000Genomes | |
| tmp_4_16889987_G_A | 214 | H>Y | No | 1000Genomes | |
| tmp_4_16889971_G_T | 219 | A>E | No | 1000Genomes | |
| ENSVATH06829886 | 229 | E>D | No | 1000Genomes | |
| tmp_4_16889777_A_C | 258 | D>E | No | 1000Genomes | |
| ENSVATH06829885 | 268 | T>A | No | 1000Genomes | |
| ENSVATH00553826 | 269 | S>C | No | 1000Genomes | |
| ENSVATH06829882 | 295 | I>T | No | 1000Genomes | |
| ENSVATH12412178 | 296 | S>G | No | 1000Genomes | |
| ENSVATH06829881 | 296 | S>I | No | 1000Genomes | |
| ENSVATH06829878 | 303 | S>A | No | 1000Genomes | |
| ENSVATH02961299 | 317 | A>S | No | 1000Genomes | |
| ENSVATH02961298 | 320 | E>D | No | 1000Genomes | |
| ENSVATH02961297 | 322 | A>V | No | 1000Genomes | |
| ENSVATH02961296 | 323 | F>L | No | 1000Genomes | |
| tmp_4_16889578_T_A | 325 | N>Y | No | 1000Genomes | |
| ENSVATH02961294 | 329 | A>S | No | 1000Genomes | |
| ENSVATH02961293 | 330 | F>Y | No | 1000Genomes | |
| ENSVATH06829875 | 344 | S>P | No | 1000Genomes | |
| ENSVATH00553823 | 345 | E>D | No | 1000Genomes | |
| tmp_4_16889305_T_G | 365 | Q>P | No | 1000Genomes | |
| ENSVATH02961287 | 367 | Q>R | No | 1000Genomes | |
| ENSVATH12412175 | 373 | T>P | No | 1000Genomes | |
| ENSVATH12412164 | 375 | N>K | No | 1000Genomes | |
| tmp_4_16889239_G_T | 387 | A>D | No | 1000Genomes | |
| ENSVATH06829874 | 397 | G>R | No | 1000Genomes | |
| ENSVATH02961284 | 424 | V>E | No | 1000Genomes | |
| ENSVATH02961285 | 424 | V>M | No | 1000Genomes | |
| ENSVATH00553822 | 431 | I>V | No | 1000Genomes | |
| ENSVATH02961283 | 437 | A>V | No | 1000Genomes | |
| ENSVATH02961282 | 446 | G>D | No | 1000Genomes | |
| tmp_4_16888947_A_G | 453 | I>T | No | 1000Genomes | |
| ENSVATH12412155 | 454 | K>N | No | 1000Genomes | |
| tmp_4_16888935_G_T | 457 | A>E | No | 1000Genomes | |
| ENSVATH02961281 | 457 | A>T | No | 1000Genomes | |
| ENSVATH09512227 | 463 | Q>H | No | 1000Genomes | |
| ENSVATH09512225 | 466 | G>A | No | 1000Genomes | |
| ENSVATH09512211 | 469 | F>I | No | 1000Genomes | |
| ENSVATH09512210 | 469 | F>L | No | 1000Genomes | |
| ENSVATH06829871 | 472 | D>N | No | 1000Genomes | |
| ENSVATH02961275 | 503 | M>V | No | 1000Genomes |
No associated diseases with F4JN35
Functions
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| calmodulin binding | Binding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states. |
| DNA-binding transcription factor activity | A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. |
| transcription cis-regulatory region binding | Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular response to osmotic stress | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. |
| negative regulation of DNA-templated transcription | Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. |
| positive regulation of defense response to bacterium | Any process that activates or increases the frequency, rate or extent of defense response to bacterium. |
| regulation of defense response | Any process that modulates the frequency, rate or extent of a defense response. |
| regulation of DNA-templated transcription | Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9M274 | NAC066 | NAC domain-containing protein 66 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q84WP6 | NAC043 | NAC domain-containing protein 43 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9C878 | BRN1 | Protein BEARSKIN1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FWX2 | NAC007 | NAC domain-containing protein 7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q5PP28 | NAC003 | NAC domain-containing protein 3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGAVSMESLP | LGFRFRPTDE | ELVNHYLRLK | INGRHSDVRV | IPDIDVCKWE | PWDLPALSVI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KTDDPEWFFF | CPRDRKYPNG | HRSNRATDSG | YWKATGKDRS | IKSKKTLIGM | KKTLVFYRGR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| APKGERTNWI | MHEYRPTLKD | LDGTSPGQSP | YVLCRLFHKP | DDRVNGVKSD | EAAFTASNKY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SPDDTSSDLV | QETPSSDAAV | EKPSDYSGGC | GYAHSNSTAD | GTMIEAPEEN | LWLSCDLEDQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KAPLPCMDSI | YAGDFSYDEI | GFQFQDGTSE | PDVSLTELLE | EVFNNPDDFS | CEESISRENP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| AVSPNGIFSS | AKMLQSAAPE | DAFFNDFMAF | TDTDAEMAQL | QYGSEGGASG | WPSDTNSYYS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DLVQQEQMIN | HNTENNLTEG | RGIKIRARQP | QNRQSTGLIN | QGIAPRRIRL | QLQSNSEVKE |
| 430 | 440 | 450 | 460 | 470 | 480 |
| REEVNEGHTV | IPEAKEAAAK | YSEKSGSLVK | PQIKLRARGT | IGQVKGERFA | DDEVQVQSRK |
| 490 | 500 | 510 | |||
| RRGGKRWKVV | ATVMVAVMVG | VGMGIWRTLV | SS |