Q5DTY9
Gene name |
Kctd16 (Gm1267, Kiaa1317) |
Protein name |
BTB/POZ domain-containing protein KCTD16 |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:383348 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q5DTY9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q5DTY9-F1 | Predicted | AlphaFoldDB |
13 variants for Q5DTY9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3389512195 | 28 | E>V | No | EVA | |
| rs3407405255 | 90 | R>S | No | EVA | |
| rs31652570 | 119 | V>I | No | EVA | |
| rs3389508546 | 318 | S>* | No | EVA | |
| rs3407406385 | 321 | S>W | No | EVA | |
| rs3408366575 | 323 | P>L | No | EVA | |
| rs3408633158 | 326 | T>A | No | EVA | |
| rs3389501551 | 331 | P>H | No | EVA | |
| rs3389514582 | 336 | S>G | No | EVA | |
| rs3389457535 | 369 | T>M | No | EVA | |
| rs3389512202 | 378 | S>N | No | EVA | |
| rs31850479 | 402 | L>M | No | EVA | |
| rs3389479173 | 403 | K>T | No | EVA |
No associated diseases with Q5DTY9
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| anchoring junction | A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix. |
| cell projection | A prolongation or process extending from a cell, e.g. a flagellum or axon. |
| postsynaptic membrane | A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane. |
| presynaptic membrane | A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane. |
| receptor complex | Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| protein homooligomerization | The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer. |
| regulation of G protein-coupled receptor signaling pathway | Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway. |
10 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q29RJ0 | KCTD18 | BTB/POZ domain-containing protein KCTD18 | Bos taurus (Bovine) | PR |
| A6H6X4 | KCTD4 | BTB/POZ domain-containing protein KCTD4 | Bos taurus (Bovine) | PR |
| Q9BQ13 | KCTD14 | BTB/POZ domain-containing protein KCTD14 | Homo sapiens (Human) | PR |
| Q8N5I3 | KCNRG | Potassium channel regulatory protein | Homo sapiens (Human) | PR |
| Q6PI47 | KCTD18 | BTB/POZ domain-containing protein KCTD18 | Homo sapiens (Human) | PR |
| Q6ZWB6 | KCTD8 | BTB/POZ domain-containing protein KCTD8 | Homo sapiens (Human) | PR |
| Q96CX2 | KCTD12 | BTB/POZ domain-containing protein KCTD12 | Homo sapiens (Human) | PR |
| Q68DU8 | KCTD16 | BTB/POZ domain-containing protein KCTD16 | Homo sapiens (Human) | PR |
| Q6WVG3 | Kctd12 | BTB/POZ domain-containing protein KCTD12 | Mus musculus (Mouse) | PR |
| Q50H33 | Kctd8 | BTB/POZ domain-containing protein KCTD8 | Mus musculus (Mouse) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MALSGNCSRY | YPRDQGAAVP | NSFPEVIELN | VGGQVYFTRH | STLISIPHSL | LWKMFSPKRD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TANDLAKDSK | GRFFIDRDGF | LFRYILDYLR | DRQVVLPDHF | PERGRLKREA | EYFQLPDLVK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LLAPEDVKQS | PDEFCHSDFE | DASQGSDTRI | CPPSSLLPHD | RKWGFITVGY | RGSCTLGREG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QADAKFRRVP | RILVCGRISL | AKEVFGETLN | ESRDPDRAPE | RYTSRFYLKF | KHLERAFDML |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SECGFHMVAC | NSSVTASFVN | QYTEDKIWSS | YTEYVFYREP | SRWSSSHCDC | CCKNGKGDKG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ESGTSCNDLS | TSSCDSQSEA | SSPQETVICG | PVTRQSNIQT | LDRPIKKGPV | QLIQQSEMRR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KSDLLRTLTS | GSRESNISSK | KKAAKEKLSI | EEELEKCIQD | FLKIKIPDRF | PERKHPWQSE |
| LLRKYHL |