A6H6X4

PR
Gene name
KCTD4
Protein name
BTB/POZ domain-containing protein KCTD4
Names
Species
Bos taurus (Bovine)
KEGG Pathway
bta:539536
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-54 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A6H6X4

Entry ID Method Resolution Chain Position Source
AF-A6H6X4-F1 Predicted AlphaFoldDB

10 variants for A6H6X4

Variant ID(s) Position Change Description Diseaes Association Provenance
rs718186650 3 H>R No EVA
rs385972594 10 K>R No EVA
rs457999641 58 F>L No EVA
rs478085720 58 F>Y No EVA
rs441133176 59 L>I No EVA
rs462404108 60 E>G No EVA
rs442288820 130 W>G No EVA
rs476880508 151 R>L No EVA
rs382362552 189 I>V No EVA
rs436919807 222 T>P No EVA

No associated diseases with A6H6X4

3 regional properties for A6H6X4

Type Name Position InterPro Accession
domain BTB/POZ domain 33 - 134 IPR000210
domain Potassium channel tetramerisation-type BTB domain 36 - 122 IPR003131
domain BTB/POZ domain-containing protein KCTD4, C-terminal 138 - 259 IPR045740

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
protein homooligomerization The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.

10 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q29RJ0 KCTD18 BTB/POZ domain-containing protein KCTD18 Bos taurus (Bovine) PR
Q9BQ13 KCTD14 BTB/POZ domain-containing protein KCTD14 Homo sapiens (Human) PR
Q8N5I3 KCNRG Potassium channel regulatory protein Homo sapiens (Human) PR
Q6PI47 KCTD18 BTB/POZ domain-containing protein KCTD18 Homo sapiens (Human) PR
Q6ZWB6 KCTD8 BTB/POZ domain-containing protein KCTD8 Homo sapiens (Human) PR
Q96CX2 KCTD12 BTB/POZ domain-containing protein KCTD12 Homo sapiens (Human) PR
Q68DU8 KCTD16 BTB/POZ domain-containing protein KCTD16 Homo sapiens (Human) PR
Q50H33 Kctd8 BTB/POZ domain-containing protein KCTD8 Mus musculus (Mouse) PR
Q5DTY9 Kctd16 BTB/POZ domain-containing protein KCTD16 Mus musculus (Mouse) PR
Q6WVG3 Kctd12 BTB/POZ domain-containing protein KCTD12 Mus musculus (Mouse) PR
10 20 30 40 50 60
MEHKINRREK EKDYEGKHNS LEDADQGKNC KSTLMTLNVG GYLYITQKQT LTKYPDTFLE
70 80 90 100 110 120
GIVNGKILCP FDADGHYFID RDGLLFRHVL NFLRNGELLL PEGFRENQLL AQEAEFFQLK
130 140 150 160 170 180
GLAEEVKSRW EKEQLTPRET TFLEITDNHD RSQGLRIFCN APDFISKIKS RIVLVSKSRL
190 200 210 220 230 240
DGFPEEFSIS SNTIQFKYFI KSENGTRLVL KEDNTFVCTL ETLKFEAIMM ALKCGFRLLT
250
SLDCSKGSIV HSDALHFIK