Q29RJ0

PR
Gene name
KCTD18
Protein name
BTB/POZ domain-containing protein KCTD18
Names
Species
Bos taurus (Bovine)
KEGG Pathway
bta:613694
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

77-152 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q29RJ0

Entry ID Method Resolution Chain Position Source
AF-Q29RJ0-F1 Predicted AlphaFoldDB

55 variants for Q29RJ0

Variant ID(s) Position Change Description Diseaes Association Provenance
rs436732303 67 Y>C No EVA
rs876487318 69 L>F No EVA
rs469590612 74 G>V No EVA
rs436045378 78 I>S No EVA
rs465825892 79 P>H No EVA
rs447812433 83 Q>K No EVA
rs477668078 84 T>P No EVA
rs459215298 92 A>D No EVA
rs450393546 117 R>T No EVA
rs465114284 125 A>G No EVA
rs456681691 126 L>* No EVA
rs468036384 127 T>R No EVA
rs438218111 127 T>S No EVA
rs449626259 129 F>V No EVA
rs479390327 130 C>R No EVA
rs479390327 130 C>S No EVA
rs470044400 130 C>S No EVA
rs466916818 131 D>E No EVA
rs209913802 132 S>L No EVA
rs478350151 146 H>D No EVA
rs462895629 170 T>S No EVA
rs443347990 175 K>N No EVA
rs482644586 176 Q>R No EVA
rs461007160 180 R>G No EVA
rs445488452 227 V>G No EVA
rs464063102 228 P>A No EVA
rs481760912 229 H>P No EVA
rs463781393 230 E>* No EVA
rs442224068 230 E>G No EVA
rs463781393 230 E>Q No EVA
rs481722765 232 I>L No EVA
rs481722765 232 I>V No EVA
rs470948290 234 C>F No EVA
rs441165493 234 C>S No EVA
rs458964339 234 C>W No EVA
rs443731509 236 T>A No EVA
rs457080334 238 E>G No EVA
rs435386960 240 R>G No EVA
rs435386960 240 R>S No EVA
rs453152658 242 L>F No EVA
rs434707418 253 R>P No EVA
rs453821850 256 R>Q No EVA
rs465530530 258 I>R No EVA
rs456736962 259 V>A No EVA
rs438261254 260 N>K No EVA
rs449177194 267 V>G No EVA
rs467007121 281 P>T No EVA
rs458531148 312 N>T No EVA
rs717928379 322 R>C No EVA
rs482983359 323 S>C No EVA
rs461287554 324 A>P No EVA
rs460151141 350 E>K No EVA
rs438226023 371 H>Q No EVA
rs715269646 382 C>S No EVA
rs433248710 395 R>T No EVA

No associated diseases with Q29RJ0

2 regional properties for Q29RJ0

Type Name Position InterPro Accession
domain Potassium channel tetramerisation-type BTB domain 14 - 98 IPR003131
domain BTB/POZ domain-containing protein KCTD18, C-terminal domain 114 - 421 IPR045704

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
protein homooligomerization The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.

10 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
A6H6X4 KCTD4 BTB/POZ domain-containing protein KCTD4 Bos taurus (Bovine) PR
Q9BQ13 KCTD14 BTB/POZ domain-containing protein KCTD14 Homo sapiens (Human) PR
Q8N5I3 KCNRG Potassium channel regulatory protein Homo sapiens (Human) PR
Q6ZWB6 KCTD8 BTB/POZ domain-containing protein KCTD8 Homo sapiens (Human) PR
Q96CX2 KCTD12 BTB/POZ domain-containing protein KCTD12 Homo sapiens (Human) PR
Q68DU8 KCTD16 BTB/POZ domain-containing protein KCTD16 Homo sapiens (Human) PR
Q6PI47 KCTD18 BTB/POZ domain-containing protein KCTD18 Homo sapiens (Human) PR
Q50H33 Kctd8 BTB/POZ domain-containing protein KCTD8 Mus musculus (Mouse) PR
Q5DTY9 Kctd16 BTB/POZ domain-containing protein KCTD16 Mus musculus (Mouse) PR
Q6WVG3 Kctd12 BTB/POZ domain-containing protein KCTD12 Mus musculus (Mouse) PR
10 20 30 40 50 60
MEGHKAEEEV LDILRLNVGG CIYTARRESL CRFKDSMLAS MFSGRFPLKT DESGACVIDR
70 80 90 100 110 120
DGHLFKYLLD YLHGEVHIPT EEQTRVALQE EADYFGIPYP YSLSDHLANE METYSLRSNI
130 140 150 160 170 180
ELKKALTDFC DSYGLVCNKP TVWVLHYLNT SGASCESRII GVYSTKTDGT DAIDKQLGGR
190 200 210 220 230 240
IHSKSIFKRE AGNNVQYIWS DYSVAELKKM MDAFDAWEGK GVSYWRVPHE LIECWTLEER
250 260 270 280 290 300
PLLGSLSHMA PIRKRRLIVN EEEEEGVNCK TGPKPVRFLG PSTSTQIKVK NSASIRVSPA
310 320 330 340 350 360
SAPQPWPRAT ANLAAGGRAV QRSAQSKVPT PVGTGLPEHP QAAQGPGAPE NGATHLPPAK
370 380 390 400 410 420
VLLSDKTATP HRVIKLRRTP LCATGSSLPA CTTPRPAGPP EPPPDALSPL GTWTENGQDQ
TK