Q4QR82
Gene name |
Rassf6 |
Protein name |
Ras association domain-containing protein 6 |
Names |
|
Species |
Rattus norvegicus (Rat) |
KEGG Pathway |
rno:305251 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q4QR82
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q4QR82-F1 | Predicted | AlphaFoldDB |
1 variants for Q4QR82
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs197420629 | 330 | Q>R | No | EVA |
No associated diseases with Q4QR82
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| apoptotic process | A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. |
| positive regulation of apoptotic process | Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process. |
| regulation of apoptotic process | Any process that modulates the occurrence or rate of cell death by apoptotic process. |
| signal transduction | The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
7 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q8WWW0 | RASSF5 | Ras association domain-containing protein 5 | Homo sapiens (Human) | PR |
| Q9NS23 | RASSF1 | Ras association domain-containing protein 1 | Homo sapiens (Human) | PR |
| Q6ZTQ3 | RASSF6 | Ras association domain-containing protein 6 | Homo sapiens (Human) | PR |
| Q5EBH1 | Rassf5 | Ras association domain-containing protein 5 | Mus musculus (Mouse) | PR |
| Q99MK9 | Rassf1 | Ras association domain-containing protein 1 | Mus musculus (Mouse) | PR |
| Q80UQ2 | Rassf6 | Ras association domain-containing protein 6 | Mus musculus (Mouse) | PR |
| O35141 | Rassf5 | Ras association domain-containing protein 5 | Rattus norvegicus (Rat) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTTMDHRFPS | RIFVNERTSI | TREQLNSLLE | TYNVFYENQK | NLHILYGQTE | DGQLIVEGML |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DIFWGVKRPI | QLKIQDEKQI | SSFDLLKSPE | TFSSKGRMTR | WGEFDDLYRI | SEMDKTQALA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PEARHTPEDY | LSCYSVLKQC | ADEEPESPLL | YRTVSEAALV | RKRMRAPEMY | RKDRMGTLAK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| HRASINGHVY | DHETSIFTPT | FGSETKVRAN | SIMKTEEVIK | QLLQKFKIEN | SPRDFALYII |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FGTGEKRKLK | KTDVPLLQRL | IQGPSKSNAR | IFLMDKDAEE | ISSDVAPYIN | FHFSFLKSIL |
| 310 | 320 | 330 | 340 | ||
| QRLDEEEKME | IERIMAKFNT | ERAFILKCLQ | SKRAAKTETT | V |