Q3SZB3

PR
Gene name
TIMM50 (TIM50)
Protein name
Mitochondrial import inner membrane translocase subunit TIM50
Names
Species
Bos taurus (Bovine)
KEGG Pathway
bta:505489
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-89 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q3SZB3

Entry ID Method Resolution Chain Position Source
AF-Q3SZB3-F1 Predicted AlphaFoldDB

No variants for Q3SZB3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q3SZB3

No associated diseases with Q3SZB3

1 regional properties for Q3SZB3

Type Name Position InterPro Accession
domain Chromosome segregation in meiosis protein 3 73 - 152 IPR012923

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion inner membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
TIM23 mitochondrial import inner membrane translocase complex The protein transport machinery of the mitochondrial inner membrane that typically transports proteins that possess a matrix-targeting N-terminal presequence. The TIM23 complex contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9D880 Timm50 Mitochondrial import inner membrane translocase subunit TIM50 Mus musculus (Mouse) PR
Q22647 scpl-4 Mitochondrial import inner membrane translocase subunit TIM50 Caenorhabditis elegans PR
Q6NWD4 timm50 Mitochondrial import inner membrane translocase subunit TIM50 Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MAASAAVFLR LRSGLRQGAR GLCARLATPP PRAPDQAAEI GSRAGTKAQT QGPQQQRSSE
70 80 90 100 110 120
GPSYAKKVAL WLARLLGAGG TVSVIYIFGN NAVDENGAKI PDEFDNDPIL VQQLRRTYKY
130 140 150 160 170 180
FKDYRQMIIE PTSPCLLPDP LREPYYQPPY TLVLELTGVL LHPEWSLATG WRFKKRPGIE
190 200 210 220 230 240
TLFQQLAPLY EIVIFTSETG MTAFPLIDSV DPHGFISYRL FRDATRYMDG HHVKDISCLN
250 260 270 280 290 300
RDPARVVVVD CKKEAFRLQP YNGVALRPWD GNSDDRVLLD LSAFLKTIAL NGVEDVRTVL
310 320 330 340 350
EHYALEEDPL EAFKQRQSRL EQEEQQRLAE LSKSSKQNLF FSSLTSRLWP RSKQP