Q3SYK4
Gene name |
Vrtn |
Protein name |
Vertnin |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:432677 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q3SYK4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q3SYK4-F1 | Predicted | AlphaFoldDB |
43 variants for Q3SYK4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3389249062 | 10 | Q>L | No | EVA | |
| rs3389243776 | 13 | R>C | No | EVA | |
| rs3389219368 | 15 | L>M | No | EVA | |
| rs3389243786 | 29 | G>A | No | EVA | |
| rs214793352 | 52 | G>S | No | EVA | |
| rs3389180335 | 59 | D>N | No | EVA | |
| rs3389243738 | 62 | A>D | No | EVA | |
| rs3389246895 | 111 | E>K | No | EVA | |
| rs3389259702 | 135 | Y>C | No | EVA | |
| rs51236513 | 157 | F>Y | No | EVA | |
| rs3389243808 | 186 | N>T | No | EVA | |
| rs3389249436 | 194 | R>H | No | EVA | |
| rs3389249076 | 195 | N>I | No | EVA | |
| rs3389210329 | 202 | F>S | No | EVA | |
| rs3389234708 | 204 | R>P | No | EVA | |
| rs3389258207 | 239 | P>R | No | EVA | |
| rs3403835876 | 247 | E>* | No | EVA | |
| rs3389251247 | 249 | D>E | No | EVA | |
| rs223920080 | 262 | G>S | No | EVA | |
| rs3389234741 | 295 | T>I | No | EVA | |
| rs3389180388 | 309 | K>R | No | EVA | |
| rs3389210391 | 314 | F>L | No | EVA | |
| rs3389245742 | 363 | L>P | No | EVA | |
| rs3389264240 | 364 | G>A | No | EVA | |
| rs236293232 | 382 | P>L | No | EVA | |
| rs254944161 | 388 | E>G | No | EVA | |
| rs3402863490 | 397 | A>T | No | EVA | |
| rs3389210383 | 404 | S>C | No | EVA | |
| rs3389245739 | 422 | N>I | No | EVA | |
| rs3389248396 | 427 | Y>* | No | EVA | |
| rs3389245723 | 428 | R>C | No | EVA | |
| rs3403641424 | 463 | F>L | No | EVA | |
| rs257491133 | 561 | G>R | No | EVA | |
| rs250875853 | 575 | Q>E | No | EVA | |
| rs215282007 | 588 | E>G | No | EVA | |
| rs227704307 | 589 | Q>R | No | EVA | |
| rs3389210361 | 607 | P>A | No | EVA | |
| rs46951543 | 631 | T>A | No | EVA | |
| rs215535713 | 636 | V>A | No | EVA | |
| rs48753874 | 653 | T>A | No | EVA | |
| rs3389249447 | 672 | G>R | No | EVA | |
| rs3389249057 | 674 | S>I | No | EVA | |
| rs3389210353 | 734 | G>S | No | EVA |
No associated diseases with Q3SYK4
1 regional properties for Q3SYK4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Vertnin-like, ovarian tumor domain | 74 - 241 | IPR047273 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| chromatin | The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| E1BP92 | VRTN | Vertnin | Bos taurus (Bovine) | PR |
| D2GZW6 | VRTN | Vertnin | Ailuropoda melanoleuca (Giant panda) | PR |
| Q9H8Y1 | VRTN | Vertnin | Homo sapiens (Human) | PR |
| E1CHH8 | VRTN | Vertnin | Sus scrofa (Pig) | PR |
| Q08C99 | vrtn | Vertnin | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTSRDQLVQQ | VLRDLQEAVE | SEGLEGLIGA | ALEAKQVLSS | FTLPICQKGG | PGAQVLEVDS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VALSLYPEDA | PRNMLPLVCK | GEGSLLFEAT | SLLLWGHTGL | SLELRARTVV | EMLLHRHYYL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QGMIDSKVML | QAVRYSLCSE | ESPEMTNLSF | ATLEAIFDAD | VKATCFPTSF | SNVWHLYALA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SILECNIYSI | YPMRNIKIRP | YFNRVIMPRC | STHVTSMLHI | MWAGQPLTSH | LFRHQYFAPV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VGLEEVEADC | TASLNPVPPN | LGPLLPPAKT | LELLNREPGL | SYSHLCDRIS | ITKSTFYRWR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RQTQEHRQKV | ATRFSAKHFL | QDSFHRGGFV | PLQQFLQRFP | EISRSTYYAW | KHELLGSGAN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SALGPATPSR | EALAVPEVER | PPGKKAAEEV | GCSSLAAAML | SPPSMILMQR | AKSFLEYCIS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LNKLVPYRCF | KCRFPGISRS | TYYNWRRKAL | RRTPSFKLSQ | AAFETAESLQ | PTDVGKETPF |
| 490 | 500 | 510 | 520 | 530 | 540 |
| SLKREAGEEE | TGKAGSGAPL | TSRGLISPKM | PLSRWQRRLR | RAARKQVLNG | HLPFCRFRLR |
| 550 | 560 | 570 | 580 | 590 | 600 |
| YPSLLPSTFW | VWKSLSRRSP | GMQIPSLSQR | RQKPQGRQKP | EGRQKPEEQQ | KPEGRQKPEG |
| 610 | 620 | 630 | 640 | 650 | 660 |
| RQKPVEPQAM | EADQNVPAMV | VPPAETLPVA | TSPEDVPGGP | SREGNIIQEA | AMTQSQPHSG |
| 670 | 680 | 690 | 700 | 710 | 720 |
| SLPSQTLAEA | PGGSDGQVLV | MDMLTTTRFK | AQAKLFLQKR | FQSKTFPSYK | EFQALFPLTA |
| 730 | |||||
| RSTYYMWKRA | LYEGLTLIDG |