E1CHH8
Gene name |
VRTN |
Protein name |
Vertnin |
Names |
|
Species |
Sus scrofa (Pig) |
KEGG Pathway |
ssc:100157734 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for E1CHH8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-E1CHH8-F1 | Predicted | AlphaFoldDB |
No variants for E1CHH8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for E1CHH8 | |||||
No associated diseases with E1CHH8
1 regional properties for E1CHH8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Vertnin-like, ovarian tumor domain | 74 - 241 | IPR047273 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| chromatin | The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| sequence-specific DNA binding | Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| E1BP92 | VRTN | Vertnin | Bos taurus (Bovine) | PR |
| D2GZW6 | VRTN | Vertnin | Ailuropoda melanoleuca (Giant panda) | PR |
| Q9H8Y1 | VRTN | Vertnin | Homo sapiens (Human) | PR |
| Q3SYK4 | Vrtn | Vertnin | Mus musculus (Mouse) | PR |
| Q08C99 | vrtn | Vertnin | Danio rerio (Zebrafish) (Brachydanio rerio) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTSREQLVLQ | VLQELQEAVE | SEGLEGLVGA | ALEAKQVLSS | FALPTCREGG | PGPQVLEVDS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VALSLYPEDA | PRNMLPLVCK | GEGSLLFEAA | SMLLWGDSGL | SLELRARTVV | EMLLHRHYYL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QGMIDSKVML | QAVRYSLCSE | ESPEMTSLPS | ATLEAIFDAD | VKATCFPSSF | SNVWHLYALA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SVLQRNIYSI | YPMRNLKIRP | YFNRVIRPRR | CDHMPATLHI | MWAGQPLTNH | LFRHQYFAPV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VGLEEVEAES | ATTSLAPTPP | ALAPLPPPAK | TLELLSQDPG | LSYSYLCERY | SVTKSTFYRW |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RRQSQEHRQK | VATRFSAKHF | LQDSFHRGGV | VPLQQFLQRF | PEISRSTYYA | WKHELLGSGT |
| 370 | 380 | 390 | 400 | 410 | 420 |
| CQALGPMEEL | EKLTEEQVAE | GLGCSSPAVS | SPGMVLMQRA | KLYLEHCISL | NTLVPYRCFK |
| 430 | 440 | 450 | 460 | 470 | 480 |
| RRFPGISRST | YYNWRRKALR | RNPSFKPAPV | LSVAGATQPA | SVGEKALLPW | EGEVGEEAGK |
| 490 | 500 | 510 | 520 | 530 | 540 |
| ATGGGQPAPR | EFLPLRMPLS | RWQRRLRREA | RKQVLSGHLP | FCRFRLRYPS | LSPSTFWVWK |
| 550 | 560 | 570 | 580 | 590 | 600 |
| SLARGWPRSL | SKLHIQAPTL | GKGGIQEVEE | KQEKEAGRNV | TAAMAPPAGT | LQMTASPGED |
| 610 | 620 | 630 | 640 | 650 | 660 |
| PGAALGGPSR | EGALQEGAMA | QGRPMVAAAG | GRDGQVLVMD | MLATTKFKAQ | AKLFLQKRFQ |
| 670 | 680 | 690 | |||
| SKSFPSYKEF | SALFPLTARS | TYYMWKRALY | DGLTLVDG |