D2GZW6

PR
Gene name
VRTN (PANDA_002667)
Protein name
Vertnin
Names
Species
Ailuropoda melanoleuca (Giant panda)
KEGG Pathway
aml:100471833
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-76 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for D2GZW6

Entry ID Method Resolution Chain Position Source
AF-D2GZW6-F1 Predicted AlphaFoldDB

No variants for D2GZW6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for D2GZW6

No associated diseases with D2GZW6

1 regional properties for D2GZW6

Type Name Position InterPro Accession
domain Vertnin-like, ovarian tumor domain 74 - 241 IPR047273

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
sequence-specific DNA binding Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

5 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
E1BP92 VRTN Vertnin Bos taurus (Bovine) PR
Q9H8Y1 VRTN Vertnin Homo sapiens (Human) PR
Q3SYK4 Vrtn Vertnin Mus musculus (Mouse) PR
E1CHH8 VRTN Vertnin Sus scrofa (Pig) PR
Q08C99 vrtn Vertnin Danio rerio (Zebrafish) (Brachydanio rerio) PR
10 20 30 40 50 60
MTSREQLVQQ VLQELQDAVE SEGLEGLVGA ALEAKQVLSS FALPTCREGG ASPQVLEVDS
70 80 90 100 110 120
VALSLYPEDA PRNMLPLACR GEGSLLFEAA SVLLWGDVGF SLELRARTVV EMLLHRHYYL
130 140 150 160 170 180
QGMIDSKVML QAVRYSLCSE ESPEMTSLPS ATLEAIFDAD VKATCFPSSF SNVWHLYALA
190 200 210 220 230 240
SVLQRNIYSI YPMRNLKIRP YFNRVIRPRR CDHVPATLHI MWAGQPLSSH LFRHQYFAPV
250 260 270 280 290 300
VGLEEVEADG APGPAPAPPA LAPLPPPAKT LELLNQEPGL SYSHLCERYS VTKSTFYRWR
310 320 330 340 350 360
RQSQEHRQKV AARFSAKHFL QDSFHRGGVV PLQQFLQRFP EISRSTYYAW KQELLGSGTC
370 380 390 400 410 420
QALAPKEVQV LGELEQLPEE QMAKGLGCSS LAAASPSMVL MQRAKSYLEH CISLNTLVPY
430 440 450 460 470 480
RCFKRRFPGI SRSTYYNWRR KALRRNPSFK PAPALSTPGA PQPASVPEEA LLPWKGEGGE
490 500 510 520 530 540
GAGKATAGGP PAPHEFLPPK VPLSRWQRRL RRAARKQVLS GHLPFCRFRL RYPSLSPSTF
550 560 570 580 590 600
WVWKSLARGW PRGLSKFQTQ APALGKGGLR EAKEKQEKEA GRDVTAAMAP PAGTPLHVGA
610 620 630 640 650 660
SPGEDPGKAQ GGPSGEGAMA QGRPHSRSLS SRPVAEAAVG GGDGQVLVMD MLATTKFKAQ
670 680 690 700
AKLFLQKRFQ SKSFPSFKEF SALFPLTARS TYYMWKRALY DGLTLVDG