Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q29078

Entry ID Method Resolution Chain Position Source
AF-Q29078-F1 Predicted AlphaFoldDB

No variants for Q29078

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q29078

No associated diseases with Q29078

No regional properties for Q29078

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q29078

Functions

Description
EC Number
Subcellular Localization
  • Secreted, extracellular space
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

1 GO annotations of molecular function

Name Definition
aspartic-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
O09043 Napsa Napsin-A Mus musculus (Mouse) PR
P08424 Ren1 Renin Rattus norvegicus (Rat) PR
Q9XEC4 APA3 Aspartic proteinase A3 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MKWLVILGLV ALSECLVIIP LTKVKSIREN LREKDLLLNF LKEHPYNMIQ KFGLKGSLCS
70 80 90 100 110 120
PKISCLRLWN YLDMVYVGNI TIGTPPQLFS VIFDTASSDL WVPSNQCHSR ACVTHRSFNP
130 140 150 160 170 180
TLSSTFQSSN RTVKLAPHSG LVSGLLGYDT VQIGRFKSEN QAFGLSQSEP VKELENAFFD
190 200 210 220 230 240
GVLGLGYPSL AIQGTTPVFD NLRKQGQIPE PVFALYLSTN TKKGSVLMIG GVDNNFFTGN
250 260 270 280 290 300
LKWVPLSARN YWQITLDRIT WRGVVVGCTR GCQAILDSGS AFLLGPSRQI SSIQKIIQAR
310 320 330 340 350 360
FIENEYQVRC CARTTLADFI FTINNVQYPV PARAYIRKGS TPRRCYSNFS GGTESLGKEE
370 380
TWILGEVFLR LYFTVFDRGQ NRIGLRIAV