Q25C36

PR
Gene name
OLFML3 (ONT1)
Protein name
Olfactomedin-like protein 3
Names
Olfactomedin-noelin-tiarin factor 1
Species
Gallus gallus (Chicken)
KEGG Pathway
gga:419882
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

43-152 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q25C36

Entry ID Method Resolution Chain Position Source
AF-Q25C36-F1 Predicted AlphaFoldDB

16 variants for Q25C36

Variant ID(s) Position Change Description Diseaes Association Provenance
rs732087703 32 L>W No Ensembl
rs315454014 42 W>G No Ensembl
rs734269491 60 V>G No Ensembl
rs738023242 180 I>V No Ensembl
rs735273140 206 V>G No Ensembl
rs732617884 216 Y>S No Ensembl
rs736143641 218 Y>S No Ensembl
rs736810206 222 Q>P No Ensembl
rs733490493 223 Q>R No Ensembl
rs734144391 238 V>G No Ensembl
rs741687114 266 D>G No Ensembl
rs734900413 309 E>G No Ensembl
rs741128106 320 V>G No Ensembl
rs738536887 326 L>P No Ensembl
rs740552080 348 S>P No Ensembl
rs737981762 371 V>G No Ensembl

No associated diseases with Q25C36

No regional properties for Q25C36

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q25C36

Functions

Description
EC Number
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

8 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q594P2 MYOC Myocilin Felis catus (Cat) (Felis silvestris catus) PR
Q9IAK4 OLFM1 Noelin Gallus gallus (Chicken) PR
Q99972 MYOC Myocilin Homo sapiens (Human) PR
Q99784 OLFM1 Noelin Homo sapiens (Human) PR
O88998 Olfm1 Noelin Mus musculus (Mouse) PR
Q80TR1 Adgrl1 Adhesion G protein-coupled receptor L1 Mus musculus (Mouse) PR
Q62609 Olfm1 Noelin Rattus norvegicus (Rat) PR
A4IIT5 olfml2a Olfactomedin-like protein 2A Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) PR
10 20 30 40 50 60
MGPWRCLLLL PLLAAAPRAQ QQQFMEYVER RLALLEERIA QWHDQSSRYS TELRDFKNQV
70 80 90 100 110 120
LGMLETAEKE REALRAEAEG AAARVDRLER EVDYLETQNP APPCVEVDEV LMEKQAATAK
130 140 150 160 170 180
QRKNEKYTKL TDCSDTIASV RAMKILKRFG SSAGLWTKDA AGSSEKIYVF DGTANDTVYI
190 200 210 220 230 240
FPRMREFTLF SATRRAARIK LPYPWVGTGH LVYGGYLYYI RQQGPFQVIK FDLANKTVVD
250 260 270 280 290 300
SSVFPAEEQI PVFGLSPFTY IELAADEEGL WAIYATKENE KNICLAKLDP DSLDIEQMWD
310 320 330 340 350 360
TPCPRENAEG AFVVCGALHV AYNTRLPSRS RVQCVFDVSG TLPPEEASLV YFPKRYGSHS
370 380 390
SMKYSPRERQ VYAWDDGYQI IYRMEMKKKL EV