Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A4IIT5

Entry ID Method Resolution Chain Position Source
AF-A4IIT5-F1 Predicted AlphaFoldDB

No variants for A4IIT5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A4IIT5

No associated diseases with A4IIT5

No regional properties for A4IIT5

Type Name Position InterPro Accession
No domain, repeats, and functional sites for A4IIT5

Functions

Description
EC Number
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular space That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

8 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q594P2 MYOC Myocilin Felis catus (Cat) (Felis silvestris catus) PR
Q25C36 OLFML3 Olfactomedin-like protein 3 Gallus gallus (Chicken) PR
Q9IAK4 OLFM1 Noelin Gallus gallus (Chicken) PR
Q99972 MYOC Myocilin Homo sapiens (Human) PR
Q99784 OLFM1 Noelin Homo sapiens (Human) PR
O88998 Olfm1 Noelin Mus musculus (Mouse) PR
Q80TR1 Adgrl1 Adhesion G protein-coupled receptor L1 Mus musculus (Mouse) PR
Q62609 Olfm1 Noelin Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MWDYKHFLLL SLAFTSTVTA LSKVLGDTDQ VRMTSEGSDC RCKCIMRPLS KEACSRVKGG
70 80 90 100 110 120
NMRVEDYYTV ETVSSGSDCK CSCTAPPSSL NPCENEWKME KMKKQAPELF KLQSMVDLLE
130 140 150 160 170 180
GTLYSMDLMK VHSYINKVVS QMNTLEETIK TNLTRENDFM KESVVNLSNQ MKKYENYSEI
190 200 210 220 230 240
MLSIKKEISN LGYQLLQKDA PENKAQDTAG VKGLAKFPNN KKNEGDKSLS KVTKDKPPKA
250 260 270 280 290 300
EKPKKEVSKT KQVPPQPTPR PRSPVLQPVV IRGVTYYKAG RQEDAENAAG NRESVVKGPH
310 320 330 340 350 360
RGAKQEIRTE GNITEPYLIR EERIVATQRA TPTPTPTTTP TTTQSTTTTT TTRTTISTAT
370 380 390 400 410 420
EYPLTTLSST VLGAEAETNK VREGECEGTI ASVEQPKKQH SYGRNEGAWM KDPIAKDGRI
430 440 450 460 470 480
YVTNYYYGNN LVEFRNLDNF KQGRWSNLYK VPYNWIGTGH VVFQGAFYYN RAFTKNIIKY
490 500 510 520 530 540
DLKQRFVAAW TLLHDVVYED TTPWKWRGHS DIDFAVDESG LWVIYPSVDY DYSQQEVIVI
550 560 570 580 590 600
SKLDPNDLSI KKETTWKTGL KRNSYGNCFI ICGILYAVDV YNQKEGMISY AYDTHTDTEA
610 620 630 640
DPKLPFINEY AFTTQIDYNP KEKVLYAWDN GHQLTYKVNF VA