P56425
Gene name |
CATHL7 (BMAP34) |
Protein name |
Cathelicidin-7 |
Names |
Antibacterial peptide BMAP-34 |
Species |
Bos taurus (Bovine) |
KEGG Pathway |
bta:317650 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P56425
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P56425-F1 | Predicted | AlphaFoldDB |
59 variants for P56425
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs474125844 | 3 | T>P | No | EVA | |
| rs455539434 | 4 | Q>R | No | EVA | |
| rs433612992 | 7 | S>R | No | EVA | |
| rs466476351 | 15 | L>M | No | EVA | |
| rs451390727 | 23 | V>L | No | EVA | |
| rs432820330 | 27 | A>S | No | EVA | |
| rs468886423 | 28 | S>C | No | EVA | |
| rs450232021 | 31 | D>A | No | EVA | |
| rs438151805 | 32 | L>P | No | EVA | |
| rs449451704 | 34 | Y>S | No | EVA | |
| rs479065698 | 36 | E>G | No | EVA | |
| rs445348176 | 39 | L>R | No | EVA | |
| rs478328649 | 41 | A>T | No | EVA | |
| rs444286361 | 43 | D>E | No | EVA | |
| rs473986495 | 44 | Q>H | No | EVA | |
| rs462056348 | 46 | N>K | No | EVA | |
| rs451224444 | 51 | E>K | No | EVA | |
| rs475349289 | 55 | Y>S | No | EVA | |
| rs456870968 | 56 | R>G | No | EVA | |
| rs438164226 | 57 | L>P | No | EVA | |
| rs438164226 | 57 | L>R | No | EVA | |
| rs467904718 | 60 | L>P | No | EVA | |
| rs467266390 | 61 | D>A | No | EVA | |
| rs467266390 | 61 | D>G | No | EVA | |
| rs434247145 | 61 | D>H | No | EVA | |
| rs463099694 | 66 | Q>* | No | EVA | |
| rs463099694 | 66 | Q>E | No | EVA | |
| rs450971810 | 66 | Q>H | No | EVA | |
| rs446647358 | 77 | V>E | No | EVA | |
| rs446647358 | 77 | V>G | No | EVA | |
| rs457969688 | 78 | S>I | No | EVA | |
| rs439426185 | 78 | S>R | No | EVA | |
| rs481642499 | 79 | F>I | No | EVA | |
| rs463159549 | 79 | F>L | No | EVA | |
| rs441543702 | 83 | E>* | No | EVA | |
| rs474741580 | 83 | E>A | No | EVA | |
| rs452967548 | 83 | E>D | No | EVA | |
| rs474741580 | 83 | E>G | No | EVA | |
| rs441543702 | 83 | E>K | No | EVA | |
| rs474741580 | 83 | E>V | No | EVA | |
| rs473581775 | 84 | T>N | No | EVA | |
| rs440636434 | 84 | T>S | No | EVA | |
| rs433423808 | 86 | C>Y | No | EVA | |
| rs469395593 | 87 | P>T | No | EVA | |
| rs457364216 | 88 | R>S | No | EVA | |
| rs435568171 | 89 | T>A | No | EVA | |
| rs435568171 | 89 | T>S | No | EVA | |
| rs468696966 | 93 | P>A | No | EVA | |
| rs446892981 | 97 | C>G | No | EVA | |
| rs479670833 | 97 | C>W | No | EVA | |
| rs464160910 | 101 | E>G | No | EVA | |
| rs474988097 | 109 | V>A | No | EVA | |
| rs453354677 | 113 | T>P | No | EVA | |
| rs445843612 | 120 | D>H | No | EVA | |
| rs448708946 | 131 | A>G | No | EVA | |
| rs718027849 | 145 | Q>E | No | EVA | |
| rs441423305 | 147 | K>* | No | EVA | |
| rs716384219 | 150 | E>V | No | EVA | |
| rs477221357 | 159 | I>M | No | EVA |
No associated diseases with P56425
5 regional properties for P56425
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | TolB, N-terminal | 28 - 121 | IPR007195 |
| repeat | WD40-like beta propeller | 202 - 227 | IPR011659-1 |
| repeat | WD40-like beta propeller | 243 - 274 | IPR011659-2 |
| repeat | WD40-like beta propeller | 283 - 318 | IPR011659-3 |
| repeat | WD40-like beta propeller | 365 - 393 | IPR011659-4 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular space | That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| lipopolysaccharide binding | Binding to a lipopolysaccharide. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| antimicrobial humoral immune response mediated by antimicrobial peptide | An immune response against microbes mediated by anti-microbial peptides in body fluid. |
| defense response to Gram-negative bacterium | Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism. |
| defense response to Gram-positive bacterium | Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism. |
| innate immune response | Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| METQRASFSL | GRSSLWLLLL | GLVVPSASAQ | DLSYREAVLR | AVDQFNERSS | EANLYRLLEL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DPPPEQDVEH | PGARKPVSFT | VKETVCPRTT | PQPPEQCDFK | ENGLVKQCVG | TVTRYWIRGD |
| 130 | 140 | 150 | 160 | ||
| FDITCNNIQS | AGLFRRLRDS | IRRGQQKILE | KARRIGERIK | DIFRG |