Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P40614

Entry ID Method Resolution Chain Position Source
AF-P40614-F1 Predicted AlphaFoldDB

No variants for P40614

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P40614

No associated diseases with P40614

4 regional properties for P40614

Type Name Position InterPro Accession
repeat Nebulin repeat 63 - 97 IPR000900-1
repeat Nebulin repeat 99 - 129 IPR000900-2
domain SH3 domain 266 - 327 IPR001452
domain Zinc finger, LIM-type 4 - 65 IPR001781

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion inner membrane; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of mitochondrial inner membrane The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
inorganic phosphate transmembrane transporter activity Enables the transfer of a inorganic phosphate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.

2 GO annotations of biological process

Name Definition
mitochondrial phosphate ion transmembrane transport The process in which a phosphate ion is transported across a mitochondrial membrane, into or out of the mitochondrion.
phosphate ion transmembrane transport The process in which a phosphate is transported across a membrane.

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P12234 SLC25A3 Phosphate carrier protein, mitochondrial Bos taurus (Bovine) PR
Q00325 SLC25A3 Phosphate carrier protein, mitochondrial Homo sapiens (Human) PR
Q8VEM8 Slc25a3 Phosphate carrier protein, mitochondrial Mus musculus (Mouse) PR
P16036 Slc25a3 Phosphate carrier protein, mitochondrial Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MSVFSQLAES SKQNPFSLPV RSGNCASAVS APGQVEFGSG KYYAYCALGG VLSCGITHTA
70 80 90 100 110 120
IVPLDLVKCR IQVNPEKYTG IATGFRTTIA EEGARALVKG WAPTLLGYSA QGLGKFGFYE
130 140 150 160 170 180
IFKNVYADML GEENAYLYRT SLYLAASASA EFFADILLAP MEATKVRIQT SPGAPPTLRG
190 200 210 220 230 240
CAPMIYKAEG LTGFYKGLPP LWMRQIPYTM MKFACFEKTV EALYQYVVPK PRAECSKAEQ
250 260 270 280 290 300
LVVTFVAGYI AGVFCAIVSH PADTVVSKLN QDSQATAGGI LKKLGFAGVW KGLVPRIIMI
310 320 330
GTLTALQWFI YDSVKVALNL PRPPPPEMPA SLKAKLAAQQ