P36054
Gene name |
RCN1 (DSCR1L, YKL159C, YKL613) |
Protein name |
Calcipressin-like protein |
Names |
Down syndrome candidate region 1-like protein, Regulator of calcineurin 1 |
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YKL159C |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P36054
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P36054-F1 | Predicted | AlphaFoldDB |
4 variants for P36054
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s11-154359 | 33 | K>R | No | SGRP | |
| s11-154177 | 94 | R>G | No | SGRP | |
| s11-154161 | 99 | Q>P | No | SGRP | |
| s11-154150 | 103 | V>I | No | SGRP |
No associated diseases with P36054
No regional properties for P36054
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P36054 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| calcium-dependent protein serine/threonine phosphatase regulator activity | Binds to and modulates of the activity of the enzyme calcium-dependent protein serine/threonine phosphatase. |
| protein phosphatase 2B binding | Binding to a protein phosphatase 2B. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| calcium-mediated signaling | Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions. |
9 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q2KIA1 | RCAN3 | Calcipressin-3 | Bos taurus (Bovine) | PR |
| Q3ZC15 | RCAN2 | Calcipressin-2 | Bos taurus (Bovine) | PR |
| Q5ZJV6 | RCAN3 | Calcipressin-3 | Gallus gallus (Chicken) | PR |
| A5A6I8 | RCAN2 | Calcipressin-2 | Pan troglodytes (Chimpanzee) | PR |
| Q9UKA8 | RCAN3 | Calcipressin-3 | Homo sapiens (Human) | PR |
| Q14206 | RCAN2 | Calcipressin-2 | Homo sapiens (Human) | PR |
| Q9JKK0 | Rcan3 | Calcipressin-3 | Mus musculus (Mouse) | PR |
| Q9JHG2 | Rcan2 | Calcipressin-2 | Mus musculus (Mouse) | PR |
| Q8CH27 | Rcan2 | Calcipressin-2 | Rattus norvegicus (Rat) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGNIITDTII | ITSDKCDIVD | NDNVERIQVW | LSKNILRKFQ | INENEPLQLI | ILKRFKRILL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ICPSHDISQH | VMDASRALEM | ENFNFSYSLQ | DGQRNLTKQY | LKVPESEKMF | LISPPASPPP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EFDFSKCEDA | PQRHIQSHIQ | QDQQQRLEAS | QLLPNNPDKN | NNGTFTLLKS | KVGAITIDRC |
| 190 | 200 | 210 | |||
| PTNDGNGQMQ | LADHVKTAFP | PKSIFDTDDD | D |