A5A6I8

PR
Gene name
RCAN2 (DSCR1L1)
Protein name
Calcipressin-2
Names
Down syndrome candidate region 1-like protein 1, Regulator of calcineurin 2
Species
Pan troglodytes (Chimpanzee)
KEGG Pathway
ptr:462742
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

121-197 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for A5A6I8

Entry ID Method Resolution Chain Position Source
AF-A5A6I8-F1 Predicted AlphaFoldDB

No variants for A5A6I8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for A5A6I8

No associated diseases with A5A6I8

1 regional properties for A5A6I8

Type Name Position InterPro Accession
domain Calcipressin-2, RNA recognition motif 11 - 87 IPR034919

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
calcium-dependent protein serine/threonine phosphatase regulator activity Binds to and modulates of the activity of the enzyme calcium-dependent protein serine/threonine phosphatase.
nucleic acid binding Binding to a nucleic acid.

1 GO annotations of biological process

Name Definition
calcium-mediated signaling Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.

9 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P36054 RCN1 Calcipressin-like protein Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q2KIA1 RCAN3 Calcipressin-3 Bos taurus (Bovine) PR
Q3ZC15 RCAN2 Calcipressin-2 Bos taurus (Bovine) PR
Q5ZJV6 RCAN3 Calcipressin-3 Gallus gallus (Chicken) PR
Q9UKA8 RCAN3 Calcipressin-3 Homo sapiens (Human) PR
Q14206 RCAN2 Calcipressin-2 Homo sapiens (Human) PR
Q9JHG2 Rcan2 Calcipressin-2 Mus musculus (Mouse) PR
Q9JKK0 Rcan3 Calcipressin-3 Mus musculus (Mouse) PR
Q8CH27 Rcan2 Calcipressin-2 Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MPAPSMDCDV STLVACVVDV EVFTNQEVKE KFEGLFRTYD DCVTFQLFKS FRRVRINFSN
70 80 90 100 110 120
PKSAARARIE LHETQFRGKK LKLYFAQVQT PETDGDKLHL APPQPAKQFL ISPPSSPPVG
130 140 150 160 170 180
WQPINDATPV LNYDLLYAVA KLGPGEKYEL HAGTESTPSV VVHVCDSDIE EEEDPKTSPK
190
PKIIQTRRPG LPPSVSN