O75182
PR
Gene name |
SIN3B |
Protein name |
Paired amphipathic helix protein Sin3b |
Names |
Histone deacetylase complex subunit Sin3b, Transcriptional corepressor Sin3b |
Species |
Homo sapiens (Human) |
KEGG Pathway |
hsa:23309 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
5 structures for O75182
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 8BPA | EM | 370 A | A | 1-1162 | PDB |
| 8BPB | EM | 280 A | A | 1-1162 | PDB |
| 8BPC | EM | 280 A | A | 1-1162 | PDB |
| 8C60 | EM | 340 A | A | 1-1162 | PDB |
| AF-O75182-F1 | Predicted | AlphaFoldDB |
785 variants for O75182
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
|
rs1446149304 CA404635977 |
2 | A>T | No |
ClinGen gnomAD |
|
|
rs1329459059 CA404635980 |
2 | A>V | No |
ClinGen gnomAD |
|
| TCGA novel | 3 | H>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA404635995 rs1235338132 |
4 | A>G | No |
ClinGen TOPMed |
|
|
rs1305780381 CA404636005 |
6 | G>C | No |
ClinGen TOPMed |
|
|
rs1305780381 CA404636003 |
6 | G>S | No |
ClinGen TOPMed |
|
|
CA306018757 rs931305537 |
6 | G>V | No |
ClinGen Ensembl |
|
|
rs371279373 CA306018761 |
8 | S>G | No |
ClinGen 1000Genomes TOPMed gnomAD |
|
|
rs937189956 CA306018763 |
8 | S>I | No |
ClinGen Ensembl |
|
|
CA404636019 rs1440004782 |
8 | S>R | No |
ClinGen gnomAD |
|
|
rs1326341173 CA404636022 |
9 | G>C | No |
ClinGen gnomAD |
|
|
rs1038431550 CA404636029 |
10 | G>A | No |
ClinGen TOPMed |
|
|
rs1038431550 CA306018765 |
10 | G>D | No |
ClinGen TOPMed |
|
|
CA306018767 rs1056992434 |
11 | S>G | No |
ClinGen TOPMed |
|
|
CA404636033 rs1372999969 |
11 | S>N | No |
ClinGen gnomAD |
|
|
CA306018769 rs895620080 |
13 | A>S | No |
ClinGen TOPMed gnomAD |
|
|
rs1287064672 CA404636072 |
17 | A>V | No |
ClinGen gnomAD |
|
|
rs1239571397 CA404636080 |
19 | R>W | No |
ClinGen TOPMed |
|
|
CA404636135 rs1355644369 |
27 | G>V | No |
ClinGen TOPMed |
|
|
rs957542038 CA306018783 |
29 | S>W | No |
ClinGen TOPMed |
|
|
rs558052777 CA306018785 |
30 | G>C | No |
ClinGen 1000Genomes |
|
|
CA404636177 rs1402181870 |
34 | H>Q | No |
ClinGen TOPMed |
|
|
CA404636201 rs1365956221 |
38 | P>L | No |
ClinGen gnomAD |
|
|
CA306018789 rs999852263 |
38 | P>S | No |
ClinGen TOPMed |
|
|
CA9282742 rs370861019 |
44 | A>T | No |
ClinGen ESP ExAC TOPMed |
|
|
CA9282744 rs747935169 |
46 | T>S | No |
ClinGen ExAC gnomAD |
|
|
CA9282746 rs777836617 |
54 | R>H | No |
ClinGen ExAC gnomAD |
|
|
CA404636454 rs1354343022 |
55 | F>S | No |
ClinGen gnomAD |
|
|
rs1162675437 CA404636473 |
57 | S>R | No |
ClinGen gnomAD |
|
|
CA9282749 rs776713378 |
58 | D>E | No |
ClinGen ExAC gnomAD |
|
|
rs770920138 CA9282748 |
58 | D>N | No |
ClinGen ExAC gnomAD |
|
|
rs1568410010 CA404636496 |
60 | A>T | No |
ClinGen Ensembl |
|
|
CA404636513 rs1568410013 |
61 | T>I | No |
ClinGen Ensembl |
|
|
CA9282750 rs746434088 |
63 | N>S | No |
ClinGen ExAC gnomAD |
|
|
CA404636540 rs1398503561 |
64 | G>S | No |
ClinGen gnomAD |
|
|
CA9282754 rs763384742 |
67 | E>G | No |
ClinGen ExAC gnomAD |
|
|
rs866523206 CA306018879 |
68 | I>T | No |
ClinGen Ensembl |
|
| TCGA novel | 69 | M>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1599583932 CA404636684 |
72 | F>V | No |
ClinGen Ensembl |
|
|
CA9282777 rs760305814 |
77 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA404637049 rs1259449664 |
78 | D>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs1364789551 CA404637123 |
83 | I>T | No |
ClinGen gnomAD |
|
|
CA306019300 rs920739323 |
84 | R>G | No |
ClinGen TOPMed |
|
|
rs1568410542 CA404637149 COSM181890 |
85 | R>C | large_intestine [Cosmic] | No |
ClinGen cosmic curated Ensembl |
|
CA9282779 rs776160582 |
85 | R>H | No |
ClinGen ExAC gnomAD |
|
|
CA9282781 rs764678519 |
87 | S>L | No |
ClinGen ExAC gnomAD |
|
|
CA404637167 rs764678519 |
87 | S>W | No |
ClinGen ExAC gnomAD |
|
|
rs1375507962 CA404637170 |
88 | Q>* | No |
ClinGen gnomAD |
|
|
CA404637169 rs1375507962 |
88 | Q>E | No |
ClinGen gnomAD |
|
|
CA404637168 rs1375507962 |
88 | Q>K | No |
ClinGen gnomAD |
|
|
CA404637191 rs1336163945 |
91 | H>D | No |
ClinGen gnomAD |
|
|
rs751363811 CA9282785 |
91 | H>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9282787 rs371285274 |
92 | E>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1039016113 COSM711327 CA306019312 |
92 | E>K | lung [Cosmic] | No |
ClinGen cosmic curated Ensembl |
|
rs1320869200 CA404637206 |
93 | H>P | No |
ClinGen TOPMed |
|
|
rs1204217350 CA404637205 |
93 | H>Y | No |
ClinGen gnomAD |
|
|
CA9282790 rs200751623 |
97 | I>M | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA9282789 rs756297307 |
97 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA404637259 rs1458357130 |
101 | N>S | No |
ClinGen TOPMed |
|
|
rs769196384 CA9282792 |
102 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA404637286 rs1431882216 |
105 | P>H | No |
ClinGen gnomAD |
|
| TCGA novel | 106 | L>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 113 | P>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA9282794 rs748515617 |
114 | K>E | No |
ClinGen ExAC gnomAD |
|
|
CA404637363 rs1189492782 |
116 | G>A | No |
ClinGen TOPMed |
|
| TCGA novel | 116 | G>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA306019326 rs933246586 |
117 | K>R | No |
ClinGen gnomAD |
|
|
CA9282796 rs368592710 |
121 | Q>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs61739673 CA404637404 |
122 | S>* | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA9282797 rs61739673 |
122 | S>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA9282826 rs766678442 |
128 | E>D | No |
ClinGen ExAC gnomAD |
|
|
rs141227814 COSM78491 CA9282827 |
130 | S>L | ovary [Cosmic] | No |
ClinGen cosmic curated ESP ExAC TOPMed gnomAD |
|
rs1386634484 CA404635330 |
131 | H>Y | No |
ClinGen gnomAD |
|
|
rs1599592150 CA404635337 |
132 | N>D | No |
ClinGen Ensembl |
|
|
CA9282829 rs558495523 |
134 | G>R | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs201238702 CA9282831 |
135 | D>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1158177059 CA404635366 |
135 | D>N | No |
ClinGen gnomAD |
|
|
rs778176585 CA9282832 |
136 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA404635383 rs1328837609 |
137 | A>T | No |
ClinGen gnomAD |
|
|
CA305985245 rs922632072 |
138 | E>Q | No |
ClinGen Ensembl |
|
| TCGA novel | 140 | F>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1568413987 CA404635433 |
141 | K>E | No |
ClinGen Ensembl |
|
|
CA404635493 rs1382150710 |
145 | P>A | No |
ClinGen gnomAD |
|
|
CA305985256 rs929991049 |
145 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
| TCGA novel | 146 | Y>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA404635501 rs1315294767 |
146 | Y>H | No |
ClinGen TOPMed |
|
|
rs1336835675 CA404635515 |
147 | K>E | No |
ClinGen gnomAD |
|
|
CA9282834 rs755809876 |
149 | D>G | No |
ClinGen ExAC gnomAD |
|
|
CA305985280 rs867819191 |
151 | P>H | No |
ClinGen Ensembl |
|
|
rs779774427 CA9282835 |
151 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA9282837 rs748849746 |
154 | P>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA404635603 rs1599592230 |
154 | P>L | No |
ClinGen Ensembl |
|
|
rs748849746 CA9282836 |
154 | P>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA404635615 rs1568414015 |
156 | E>Q | No |
ClinGen Ensembl |
|
|
rs778232037 CA9282838 |
158 | D>N | No |
ClinGen ExAC gnomAD |
|
|
rs374226924 CA9282840 |
160 | V>L | No |
ClinGen ESP ExAC gnomAD |
|
|
CA9282839 rs374226924 |
160 | V>M | No |
ClinGen ESP ExAC gnomAD |
|
|
CA404635698 rs1301642673 |
163 | N>S | No |
ClinGen gnomAD |
|
|
CA9282842 rs760524139 |
164 | N>D | No |
ClinGen ExAC gnomAD |
|
|
CA404635820 rs1402177322 |
174 | T>N | No |
ClinGen gnomAD |
|
| TCGA novel | 175 | R>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 175 | R>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1424154797 CA404635832 |
176 | F>Y | No |
ClinGen TOPMed |
|
| TCGA novel | 184 | R>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs764562241 CA9282849 |
192 | T>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs764562241 CA404635945 |
192 | T>R | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 199 | N>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA404636638 rs1490407830 |
199 | N>S | No |
ClinGen TOPMed |
|
|
rs1270614718 CA404636667 |
200 | T>M | No |
ClinGen TOPMed |
|
|
CA9282876 rs777353760 |
200 | T>S | No |
ClinGen ExAC gnomAD |
|
|
rs1410781598 CA404636669 |
201 | R>G | No |
ClinGen gnomAD |
|
|
rs749428149 CA305989991 |
202 | G>V | No |
ClinGen Ensembl |
|
|
rs757136055 CA9282878 |
203 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs959675144 CA305990002 |
203 | R>W | No |
ClinGen Ensembl |
|
|
rs557026752 CA404636710 |
204 | P>A | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA9282879 rs557026752 |
204 | P>S | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA9282881 rs769582749 |
206 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
rs749442231 CA9282883 |
208 | M>V | No |
ClinGen ExAC gnomAD |
|
|
rs1267941253 CA404636788 |
209 | S>Y | No |
ClinGen gnomAD |
|
| TCGA novel | 210 | E>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs991469404 CA305990023 |
211 | E>K | No |
ClinGen Ensembl |
|
|
CA404636835 rs1599595438 |
213 | V>G | No |
ClinGen Ensembl |
|
| TCGA novel | 215 | T>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1276375760 CA404636860 |
216 | E>K | No |
ClinGen TOPMed |
|
|
rs762377285 CA9282886 |
219 | N>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs773679004 CA9282888 |
222 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs760970783 CA9282889 |
233 | Q>H | No |
ClinGen ExAC gnomAD |
|
|
CA9282892 rs758067163 |
237 | E>K | No |
ClinGen ExAC gnomAD |
|
|
rs751080871 CA9282894 |
239 | K>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9282895 rs751080871 |
239 | K>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA404637124 rs1384662339 |
240 | R>Q | No |
ClinGen TOPMed gnomAD |
|
|
CA404637743 rs1202925745 |
244 | T>I | No |
ClinGen TOPMed gnomAD |
|
|
CA404637745 rs1202925745 |
244 | T>R | No |
ClinGen TOPMed gnomAD |
|
|
TCGA novel CA9282925 rs200695908 |
247 | G>R | Variant assessed as Somatic; 0.0 impact. Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs137867126 CA9282927 |
248 | P>L | No |
ClinGen ESP ExAC gnomAD |
|
|
rs747529358 CA9282926 |
248 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs770242845 CA9282930 |
250 | E>K | No |
ClinGen ExAC gnomAD |
|
|
rs1174870718 CA404637842 |
251 | M>I | No |
ClinGen gnomAD |
|
|
rs1480417935 CA404637834 |
251 | M>L | No |
ClinGen gnomAD |
|
|
CA404637853 rs1403289269 |
252 | H>R | No |
ClinGen gnomAD |
|
|
rs1471777740 CA404637861 |
253 | S>G | No |
ClinGen TOPMed |
|
|
rs773875029 CA9282932 |
253 | S>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs372704525 CA9282933 |
254 | V>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA305994117 rs372704525 |
254 | V>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA9282935 rs749942191 |
255 | Q>P | No |
ClinGen ExAC gnomAD |
|
|
CA404637913 rs1308963464 |
256 | K>N | No |
ClinGen gnomAD |
|
|
CA404637932 rs1568417266 |
258 | E>D | No |
ClinGen Ensembl |
|
|
rs753729355 CA9282939 |
260 | D>N | No |
ClinGen ExAC gnomAD |
|
|
CA9282940 rs754803648 |
261 | K>E | No |
ClinGen ExAC gnomAD |
|
|
rs778612005 CA9282941 |
262 | T>N | No |
ClinGen ExAC gnomAD |
|
|
rs752875974 CA9282942 |
263 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs1291049951 CA404637962 |
263 | P>T | No |
ClinGen TOPMed |
|
|
CA305994229 rs1014327928 |
264 | E>A | No |
ClinGen TOPMed |
|
|
CA305994230 rs1014327928 |
264 | E>G | No |
ClinGen TOPMed |
|
|
rs895847991 CA305994224 |
264 | E>Q | No |
ClinGen Ensembl |
|
| TCGA novel | 265 | H>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
RCV000970757 rs61754499 CA9282946 |
266 | S>G | No |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs1435161474 CA404637990 |
267 | R>S | No |
ClinGen TOPMed |
|
|
CA9282947 rs148249040 |
269 | R>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA9282948 rs746309643 |
269 | R>H | No |
ClinGen ExAC gnomAD |
|
|
rs563163448 CA9282949 |
271 | R>Q | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs1056689692 CA305994246 |
271 | R>W | No |
ClinGen TOPMed gnomAD |
|
|
rs771722027 CA9282952 |
272 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA404638023 rs1370973429 |
273 | S>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA9282956 rs776558509 |
274 | L>F | No |
ClinGen ExAC gnomAD |
|
|
rs1347385300 CA404638029 |
275 | L>F | No |
ClinGen gnomAD |
|
|
rs759412750 CA9282957 |
276 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9282958 rs765001220 |
276 | R>H | No |
ClinGen ExAC gnomAD |
|
|
rs752534796 CA9282959 |
277 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs751691634 CA9282962 |
278 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 279 | S>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA404638060 rs1359174922 |
280 | A>V | No |
ClinGen gnomAD |
|
|
rs781358567 CA9282964 |
281 | P>S | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs141789662 CA9282966 |
282 | A>T | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs780320420 CA9282967 |
283 | K>Q | No |
ClinGen ExAC gnomAD |
|
|
rs1458737122 CA404638267 |
284 | K>R | No |
ClinGen gnomAD |
|
| TCGA novel | 286 | M>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA9282985 rs200050344 |
286 | M>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA404638330 rs1450785633 |
288 | L>P | No |
ClinGen TOPMed gnomAD |
|
|
rs551562375 COSM284997 CA9282986 |
289 | R>C | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
rs551562375 CA404638335 |
289 | R>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1053297603 CA305995950 |
289 | R>H | No |
ClinGen TOPMed |
|
| TCGA novel | 293 | D>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1417811688 CA404638394 |
294 | L>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA9282987 rs779094465 |
296 | I>F | No |
ClinGen ExAC gnomAD |
|
|
CA9282989 rs542264653 |
297 | A>T | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA404638469 rs1184533893 |
301 | K>T | No |
ClinGen Ensembl |
|
|
CA404638516 rs1201418508 |
305 | L>V | No |
ClinGen gnomAD |
|
| TCGA novel | 306 | Q>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1238776793 CA404638625 |
313 | K>E | No |
ClinGen gnomAD |
|
|
rs780851133 CA9283008 |
315 | R>C | No |
ClinGen ExAC gnomAD |
|
|
rs745454131 CA9283009 |
315 | R>H | No |
ClinGen ExAC gnomAD |
|
|
CA305996807 rs779413580 |
316 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9283011 rs779413580 |
316 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs749314867 CA9283012 |
319 | K>R | No |
ClinGen ExAC gnomAD |
|
|
CA305996817 rs1005646171 |
322 | E>G | No |
ClinGen TOPMed |
|
|
CA9283013 rs768446761 |
323 | V>A | No |
ClinGen ExAC gnomAD |
|
|
rs774335992 CA9283014 |
325 | E>K | No |
ClinGen ExAC gnomAD |
|
|
CA9283016 rs771955339 |
329 | R>C | No |
ClinGen ExAC gnomAD |
|
|
CA305996867 rs368177077 |
329 | R>H | No |
ClinGen ESP TOPMed |
|
|
rs1271959820 CA404638880 |
331 | I>V | No |
ClinGen gnomAD |
|
|
COSM438853 CA9283018 rs760752165 |
332 | A>T | Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA TOPMed gnomAD |
|
CA404638903 rs1200893243 |
334 | F>L | No |
ClinGen gnomAD |
|
|
rs754895779 CA9283020 |
334 | F>Y | No |
ClinGen ExAC gnomAD |
|
|
rs760132977 CA9283021 |
335 | N>S | No |
ClinGen ExAC gnomAD |
|
|
rs1283417746 CA404638915 |
336 | Q>R | No |
ClinGen TOPMed |
|
|
rs753160742 CA404638933 |
339 | V>L | No |
ClinGen ExAC gnomAD |
|
|
CA9283023 rs753160742 |
339 | V>M | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 341 | G>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA404638951 rs1163415255 |
342 | S>A | No |
ClinGen gnomAD |
|
|
rs758763160 CA9283024 |
342 | S>F | No |
ClinGen ExAC gnomAD |
|
|
CA9283025 rs778051465 |
348 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9283026 rs750144359 |
350 | P>R | No |
ClinGen ExAC gnomAD |
|
|
rs753487544 CA9283049 |
354 | K>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA404640033 rs1262164722 |
355 | F>C | No |
ClinGen gnomAD |
|
|
CA9283051 rs778510867 |
356 | P>A | No |
ClinGen ExAC gnomAD |
|
|
CA9283052 rs778510867 |
356 | P>T | No |
ClinGen ExAC gnomAD |
|
|
rs200523165 CA9283053 |
360 | A>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1444331011 CA404640072 |
361 | Q>R | No |
ClinGen gnomAD |
|
| TCGA novel | 368 | V>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA404640132 rs1484461995 |
370 | E>Q | No |
ClinGen gnomAD |
|
|
CA404640142 rs142026795 |
371 | L>P | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs142026795 CA9283057 |
371 | L>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA404640155 rs139223639 |
373 | F>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA9283058 rs746041626 |
373 | F>V | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 373 | F>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA9283060 rs149533205 |
374 | A>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs369206489 CA9283061 COSM288353 |
374 | A>V | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA404640170 rs1568421324 |
376 | P>R | No |
ClinGen Ensembl |
|
|
CA9283062 rs187200428 |
377 | M>T | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA9283064 rs762114000 |
379 | D>N | No |
ClinGen ExAC gnomAD |
|
|
CA9283065 rs767857856 |
381 | S>P | No |
ClinGen ExAC gnomAD |
|
|
CA306003184 rs1053413041 |
382 | G>R | No |
ClinGen TOPMed gnomAD |
|
|
rs754665574 CA9283067 |
383 | D>N | No |
ClinGen ExAC gnomAD |
|
|
COSM1225755 CA9283069 rs752227470 |
384 | G>R | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA404640224 rs1481788083 |
385 | I>L | No |
ClinGen TOPMed |
|
|
CA9283072 rs746927268 |
386 | S>G | No |
ClinGen ExAC gnomAD |
|
|
CA404640240 rs781024383 |
387 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs781024383 CA9283074 |
387 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9283073 rs564988933 |
387 | R>W | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA9283075 rs746152842 |
389 | I>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA306003217 rs200564763 |
390 | D>N | No |
ClinGen TOPMed |
|
|
rs780156941 CA9283077 |
393 | S>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
COSM992588 CA404640299 rs1172751156 |
396 | R>C | Variant assessed as Somatic; 0.0 impact. large_intestine endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed gnomAD |
|
CA9283078 rs749391401 |
396 | R>L | No |
ClinGen ExAC gnomAD |
|
|
rs1309789244 CA404640306 |
397 | I>T | No |
ClinGen gnomAD |
|
| TCGA novel | 400 | S>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA404640341 rs1404226048 |
402 | R>Q | No |
ClinGen gnomAD |
|
|
CA404640592 rs1234285002 |
408 | Y>C | No |
ClinGen gnomAD |
|
|
rs1599605669 CA404640634 |
411 | P>H | No |
ClinGen Ensembl |
|
|
CA9283082 rs772379581 |
412 | K>R | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 414 | S>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 416 | R>K | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 416 | R>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1568421455 CA404640743 |
419 | I>N | No |
ClinGen Ensembl |
|
|
CA9283102 rs370940671 |
423 | L>F | No |
ClinGen ESP ExAC gnomAD |
|
|
rs1437573766 CA404640843 |
424 | D>N | No |
ClinGen gnomAD |
|
|
CA404640853 rs1401494256 |
425 | H>Y | No |
ClinGen TOPMed |
|
|
RCV000880686 rs144873823 CA9283104 |
426 | W>* | No |
ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD |
|
|
rs1315256744 CA404640872 |
427 | T>I | No |
ClinGen TOPMed gnomAD |
|
|
rs1322921887 CA404640875 |
428 | L>F | No |
ClinGen gnomAD |
|
|
CA306003510 rs1027522366 |
430 | Q>* | No |
ClinGen TOPMed gnomAD |
|
|
rs772602173 CA9283105 |
430 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
CA404640901 rs1210219692 |
432 | S>W | No |
ClinGen gnomAD |
|
|
CA9283107 rs761147809 |
434 | T>I | No |
ClinGen ExAC gnomAD |
|
|
rs1179973162 CA404640920 |
435 | D>A | No |
ClinGen TOPMed gnomAD |
|
|
CA9283110 rs762650758 |
436 | D>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA404640927 rs762650758 |
436 | D>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9283109 rs775289310 |
436 | D>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs763576604 CA9283111 |
437 | Y>F | No |
ClinGen ExAC gnomAD |
|
|
rs1458826184 CA404640962 |
441 | K>E | No |
ClinGen gnomAD |
|
| TCGA novel | 445 | T>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs767511824 CA9283114 |
446 | C>* | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9283113 rs761701383 |
446 | C>F | No |
ClinGen ExAC |
|
|
CA404641021 rs754372470 |
449 | P>A | No |
ClinGen gnomAD |
|
|
CA306003560 rs754372470 |
449 | P>S | No |
ClinGen gnomAD |
|
|
CA306003556 rs754372470 |
449 | P>T | No |
ClinGen gnomAD |
|
|
CA9283115 rs750321022 |
451 | Y>C | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 453 | A>V | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA404641160 rs1298585259 |
458 | D>V | No |
ClinGen TOPMed |
|
|
rs776639335 CA404641197 |
463 | F>L | No |
ClinGen ExAC gnomAD |
|
|
rs1212319094 CA404641255 |
472 | F>V | No |
ClinGen TOPMed gnomAD |
|
|
CA9283175 rs775114267 |
473 | V>I | No |
ClinGen ExAC gnomAD |
|
|
CA306004135 rs894438012 |
476 | K>R | No |
ClinGen TOPMed |
|
|
rs746657713 COSM1712004 CA306004155 |
479 | P>L | skin [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
rs1267078181 CA404641307 |
480 | Y>H | No |
ClinGen TOPMed |
|
|
rs751788314 COSM992596 CA9283178 |
481 | E>K | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
rs1178178519 CA404641353 |
486 | R>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
| TCGA novel | 490 | E>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA306004193 rs907257212 |
490 | E>K | No |
ClinGen Ensembl |
|
|
CA9283199 rs750439502 |
500 | T>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA404641470 rs1599607961 |
501 | N>T | No |
ClinGen Ensembl |
|
|
rs371214693 CA9283203 |
505 | I>V | No |
ClinGen ESP ExAC gnomAD |
|
|
CA404641500 rs1418982296 |
506 | R>C | No |
ClinGen gnomAD |
|
| TCGA novel | 506 | R>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1482387474 CA404641521 |
509 | E>G | No |
ClinGen gnomAD |
|
|
rs765530665 CA9283204 |
515 | L>M | No |
ClinGen ExAC gnomAD |
|
|
CA404641575 TCGA novel rs1599608003 |
517 | R>Q | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA Ensembl |
|
CA404641579 rs945798851 |
518 | M>L | No |
ClinGen gnomAD |
|
|
CA306008660 rs945798851 |
518 | M>V | No |
ClinGen gnomAD |
|
|
CA404641586 rs1326282640 |
519 | A>T | No |
ClinGen gnomAD |
|
|
rs745765809 CA9283207 |
519 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs755608060 CA9283209 |
520 | P>L | Variant assessed as Somatic; 4.64e-05 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs1428130477 CA404641598 |
521 | E>* | No |
ClinGen gnomAD |
|
|
CA404641604 rs1269220728 |
522 | D>N | No |
ClinGen gnomAD |
|
|
CA404641614 COSM1680782 rs1427765806 |
523 | Q>* | large_intestine [Cosmic] | No |
ClinGen cosmic curated gnomAD |
|
rs1427765806 CA404641613 |
523 | Q>E | No |
ClinGen gnomAD |
|
| TCGA novel | 524 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1397319820 CA404641645 |
527 | R>G | No |
ClinGen TOPMed gnomAD |
|
|
CA404641646 rs1386341756 |
527 | R>Q | No |
ClinGen gnomAD |
|
|
CA404641644 rs1397319820 |
527 | R>W | No |
ClinGen TOPMed gnomAD |
|
|
CA404641658 rs1427221175 |
529 | D>G | No |
ClinGen Ensembl |
|
|
rs774283092 CA9283213 |
530 | D>N | No |
ClinGen ExAC gnomAD |
|
|
CA404641697 rs1280692739 |
535 | T>M | No |
ClinGen gnomAD |
|
|
CA9283215 rs772162952 |
536 | S>L | No |
ClinGen ExAC gnomAD |
|
|
rs1290962626 CA404641705 |
537 | E>Q | No |
ClinGen gnomAD |
|
|
rs1599608092 CA404641716 |
538 | V>G | No |
ClinGen Ensembl |
|
|
CA9283218 rs766416335 |
539 | I>N | No |
ClinGen ExAC gnomAD |
|
|
CA404641718 rs1252349682 |
539 | I>V | No |
ClinGen gnomAD |
|
|
CA9283220 rs760026073 |
541 | R>C | No |
ClinGen ExAC gnomAD |
|
|
CA404641733 rs1455347133 |
541 | R>H | No |
ClinGen gnomAD |
|
|
CA9283221 rs565050507 |
542 | R>H | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1241722646 CA404641758 |
545 | Y>C | No |
ClinGen TOPMed gnomAD |
|
|
CA404641763 rs1389356208 |
546 | R>C | No |
ClinGen gnomAD |
|
|
rs1382475708 CA404641779 |
548 | Y>C | No |
ClinGen TOPMed |
|
|
CA9283224 rs767103432 |
551 | K>R | No |
ClinGen ExAC gnomAD |
|
|
CA9283225 rs201411175 |
553 | P>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
| TCGA novel | 553 | P>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA9283228 rs368153359 |
556 | I>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA404641836 rs1320056070 |
557 | E>K | No |
ClinGen gnomAD |
|
|
rs754934495 CA9283229 |
558 | S>I | No |
ClinGen ExAC gnomAD |
|
|
rs1231154237 CA404641866 |
561 | K>E | No |
ClinGen TOPMed gnomAD |
|
|
rs1296739906 CA404641871 |
561 | K>N | No |
ClinGen gnomAD |
|
|
CA404641877 rs1321690370 |
562 | N>S | No |
ClinGen gnomAD |
|
|
CA404641883 rs1263195610 |
563 | P>S | No |
ClinGen gnomAD |
|
|
rs1213935583 CA404641894 |
565 | T>A | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 566 | A>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA404641916 rs1463265701 |
568 | P>L | No |
ClinGen gnomAD |
|
|
rs371313884 CA9283233 |
569 | V>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs769795328 CA404641985 |
577 | K>N | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 580 | E>G | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs775986985 CA9283265 |
582 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
CA9283266 rs77862089 |
583 | E>G | No |
ClinGen ExAC gnomAD |
|
|
rs768967960 CA9283268 |
584 | A>G | No |
ClinGen ExAC gnomAD |
|
|
rs1431622760 CA404642064 |
588 | F>L | No |
ClinGen gnomAD |
|
|
CA404642099 rs774746144 |
593 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA404642117 rs1568423325 |
595 | Q>H | No |
ClinGen Ensembl |
|
|
rs766152964 CA9283271 |
596 | Y>F | No |
ClinGen ExAC gnomAD |
|
|
rs150614695 CA306009157 |
598 | K>R | No |
ClinGen ESP |
|
|
rs753502048 CA9283272 |
599 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs865969150 COSM992599 CA306009179 |
601 | L>F | Variant assessed as Somatic; impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated Ensembl NCI-TCGA |
|
rs1454893688 CA404642158 |
601 | L>R | No |
ClinGen TOPMed |
|
|
rs1352271750 CA404642174 |
604 | L>V | No |
ClinGen gnomAD |
|
| TCGA novel | 605 | D>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
| TCGA novel | 612 | K>E | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1414843531 CA404642282 |
614 | N>D | No |
ClinGen gnomAD |
|
|
CA404642324 rs1157891024 |
616 | T>I | No |
ClinGen TOPMed |
|
|
rs777472916 CA9283278 |
621 | S>C | No |
ClinGen ExAC gnomAD |
|
|
rs1348277108 CA404642399 |
623 | S>G | No |
ClinGen gnomAD |
|
|
CA404642435 rs1272315695 |
625 | L>R | No |
ClinGen gnomAD |
|
|
rs1181459328 CA404642458 |
627 | E>V | No |
ClinGen TOPMed |
|
|
CA9283283 rs765828024 |
630 | S>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs765828024 CA306009202 |
630 | S>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs749797171 CA9283285 |
631 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs769470249 CA9283310 |
638 | Q>R | No |
ClinGen ExAC TOPMed |
|
|
CA404642930 rs1599611206 |
639 | H>P | No |
ClinGen Ensembl |
|
|
rs774961122 CA9283311 |
640 | S>L | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA404642949 rs1328809884 |
642 | G>S | No |
ClinGen gnomAD |
|
|
rs774327119 CA9283314 |
643 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9283315 rs761732809 |
643 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1425130897 CA404642960 |
644 | S>C | No |
ClinGen TOPMed |
|
|
CA404642963 rs1447878569 |
644 | S>N | No |
ClinGen gnomAD |
|
|
rs767339010 CA9283316 |
645 | A>G | No |
ClinGen ExAC gnomAD |
|
|
rs1187477874 CA404642966 |
645 | A>T | No |
ClinGen gnomAD |
|
|
CA404642970 rs767339010 |
645 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs140033053 CA9283317 |
646 | P>A | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA9283318 rs140033053 |
646 | P>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA9283320 rs372471646 |
647 | S>C | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA306011176 rs372471646 |
647 | S>F | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA306011178 rs974392592 |
648 | S>G | No |
ClinGen gnomAD |
|
|
CA9283323 rs748733538 |
650 | P>A | No |
ClinGen ExAC gnomAD |
|
|
rs1416518095 CA404643009 |
652 | L>F | No |
ClinGen gnomAD |
|
|
CA9283327 rs771163677 |
657 | E>K | No |
ClinGen ExAC gnomAD |
|
|
CA9283330 rs748875994 |
659 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9283329 rs748875994 |
659 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs779766057 CA9283328 |
659 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs773816761 CA9283331 |
661 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA404643104 rs1370470959 |
666 | A>G | No |
ClinGen gnomAD |
|
|
CA9283334 rs773092558 |
667 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA306011194 rs914745773 |
669 | I>V | No |
ClinGen gnomAD |
|
|
CA9283338 rs759674357 |
670 | S>N | No |
ClinGen ExAC gnomAD |
|
|
rs758507003 CA9283341 |
673 | V>A | No |
ClinGen ExAC gnomAD |
|
|
rs752805696 CA9283340 |
673 | V>M | No |
ClinGen ExAC gnomAD |
|
|
rs1599611404 CA404643154 |
674 | K>R | No |
ClinGen Ensembl |
|
|
CA9283343 rs752051287 |
675 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
rs778459904 CA9283342 |
675 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9283344 rs757694156 |
677 | P>A | No |
ClinGen ExAC gnomAD |
|
|
CA9283345 rs143042146 |
677 | P>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA306011212 rs868181786 |
678 | A>T | No |
ClinGen Ensembl |
|
|
CA404643194 rs1235686746 |
681 | K>E | No |
ClinGen gnomAD |
|
|
CA306011213 rs932290796 |
681 | K>R | No |
ClinGen Ensembl |
|
|
CA404643200 rs1568424877 |
682 | E>K | No |
ClinGen Ensembl |
|
|
CA404643213 rs1599611472 |
683 | D>A | No |
ClinGen Ensembl |
|
|
rs1210502840 CA404643233 |
685 | G>A | No |
ClinGen TOPMed |
|
|
CA404643237 rs1479939529 |
686 | T>A | No |
ClinGen gnomAD |
|
|
rs1479939529 CA404643236 |
686 | T>P | No |
ClinGen gnomAD |
|
|
rs1252016707 CA404643243 |
687 | I>V | No |
ClinGen gnomAD |
|
|
CA404643252 rs1599611492 |
688 | H>P | No |
ClinGen Ensembl |
|
|
CA404643259 rs1195226542 |
689 | Q>* | No |
ClinGen gnomAD |
|
|
rs1393045271 CA404643262 |
689 | Q>R | No |
ClinGen gnomAD |
|
|
rs1599611515 CA404643278 |
692 | H>P | No |
ClinGen Ensembl |
|
|
CA404643275 rs1174020181 |
692 | H>Y | No |
ClinGen gnomAD |
|
|
CA404643297 rs770828485 |
694 | F>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1300020505 CA404643299 |
695 | V>L | No |
ClinGen gnomAD |
|
|
CA404643301 rs1300020505 |
695 | V>M | No |
ClinGen gnomAD |
|
|
CA404643311 rs1232859650 |
697 | S>R | No |
ClinGen TOPMed |
|
|
rs776260371 CA9283356 |
705 | D>G | No |
ClinGen ExAC gnomAD |
|
|
rs776260371 CA9283355 |
705 | D>V | No |
ClinGen ExAC gnomAD |
|
|
CA9283357 rs373630570 |
707 | G>R | No |
ClinGen ESP ExAC gnomAD |
|
| TCGA novel | 708 | A>T | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA404643398 rs1297278286 |
710 | E>K | No |
ClinGen gnomAD |
|
|
rs752172943 CA9283361 |
713 | A>P | No |
ClinGen ExAC gnomAD |
|
|
rs1391584480 CA404643439 |
716 | D>N | No |
ClinGen TOPMed |
|
|
CA9283362 rs757671077 |
717 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
CA306011226 rs997851710 |
717 | R>W | No |
ClinGen TOPMed gnomAD |
|
|
CA404643450 rs1030127335 |
718 | D>H | No |
ClinGen TOPMed gnomAD |
|
|
CA306011232 rs1030127335 |
718 | D>N | No |
ClinGen TOPMed gnomAD |
|
|
rs781655251 CA9283363 |
719 | S>G | No |
ClinGen ExAC gnomAD |
|
|
rs1194070983 CA404643467 |
720 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs1599611612 CA404643500 |
725 | T>P | No |
ClinGen Ensembl |
|
|
rs888966721 CA306011238 |
727 | P>S | No |
ClinGen TOPMed |
|
|
CA404643524 rs1165925378 |
728 | S>R | No |
ClinGen TOPMed |
|
|
CA404643520 rs1172360232 |
728 | S>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA9283366 rs778540375 |
730 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs756459568 CA9283365 |
730 | R>W | Variant assessed as Somatic; 4.742e-05 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs757962198 CA9283368 |
732 | K>N | No |
ClinGen ExAC gnomAD |
|
|
rs747740803 CA9283367 |
732 | K>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA404643551 rs1462139773 |
733 | P>A | No |
ClinGen gnomAD |
|
|
CA9283369 rs145531447 |
733 | P>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA9283370 rs747009462 |
734 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1340386230 CA404643575 |
737 | P>S | No |
ClinGen gnomAD |
|
|
CA9283374 rs769649897 |
739 | S>T | No |
ClinGen ExAC |
|
|
rs755848169 CA9283375 |
741 | P>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA404643631 rs755848169 |
741 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1259930531 CA404643650 |
742 | P>L | No |
ClinGen TOPMed gnomAD |
|
|
CA404643647 rs1259930531 |
742 | P>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs981410828 CA306011267 |
744 | E>K | No |
ClinGen Ensembl |
|
|
CA9283378 rs774271087 |
745 | K>N | No |
ClinGen ExAC gnomAD |
|
|
CA9283377 rs764307148 |
745 | K>Q | No |
ClinGen ExAC gnomAD |
|
|
rs761901233 CA9283379 |
746 | G>R | No |
ClinGen ExAC gnomAD |
|
|
rs767939881 CA9283380 |
747 | A>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs756484758 CA9283382 |
749 | G>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA404643759 rs1369429775 |
750 | D>E | No |
ClinGen TOPMed |
|
|
rs1158574825 CA404643747 |
750 | D>H | No |
ClinGen gnomAD |
|
|
rs958134578 CA306011270 |
751 | A>S | No |
ClinGen TOPMed |
|
|
rs752386239 CA9283384 |
752 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA404643773 rs1455732655 |
752 | P>S | No |
ClinGen gnomAD |
|
|
rs777321270 CA9283386 |
754 | T>A | No |
ClinGen ExAC gnomAD |
|
|
CA9283387 rs140965755 |
758 | P>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1290928985 CA404643853 |
758 | P>S | No |
ClinGen gnomAD |
|
|
rs866589325 CA306011301 |
759 | L>P | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen Ensembl NCI-TCGA |
|
rs564862555 CA9283388 |
760 | P>L | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA9283390 rs61761939 |
761 | P>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1217726755 CA404643914 |
763 | A>G | No |
ClinGen gnomAD |
|
|
COSM1225763 rs769755250 CA9283391 |
764 | P>L | large_intestine [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs749582841 CA9283393 |
765 | H>Q | No |
ClinGen ExAC gnomAD |
|
|
CA306011309 rs547023509 |
766 | K>E | No |
ClinGen 1000Genomes gnomAD |
|
| TCGA novel | 766 | K>N | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA9283394 rs117307745 |
767 | P>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1176680543 CA404643948 |
767 | P>S | No |
ClinGen gnomAD |
|
|
rs1599611836 CA404643970 |
770 | D>E | No |
ClinGen Ensembl |
|
|
rs761831913 CA9283397 |
770 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs767585468 CA9283398 |
771 | V>I | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs773641631 CA9283399 |
774 | L>I | No |
ClinGen ExAC gnomAD |
|
|
rs1437492650 CA404644011 |
776 | F>L | No |
ClinGen TOPMed |
|
|
rs180697016 CA306011328 |
777 | A>G | No |
ClinGen 1000Genomes ExAC |
|
|
CA9283400 rs180697016 |
777 | A>V | No |
ClinGen 1000Genomes ExAC |
|
|
rs1279696115 CA404644020 |
778 | N>S | No |
ClinGen TOPMed |
|
|
rs1213483828 CA404644081 |
786 | R>H | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed |
|
rs1213483828 CA404644083 |
786 | R>L | No |
ClinGen TOPMed |
|
|
rs1568425193 CA404644091 |
788 | H>Y | No |
ClinGen Ensembl |
|
|
rs766795332 CA9283401 |
789 | Q>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA404644107 rs1376578192 |
790 | T>I | No |
ClinGen gnomAD |
|
| TCGA novel | 793 | S>F | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs922155841 CA306011361 |
794 | R>G | No |
ClinGen Ensembl |
|
|
CA404644149 rs1259209117 |
797 | K>R | No |
ClinGen TOPMed gnomAD |
|
|
rs933602338 CA306011374 |
799 | Y>C | No |
ClinGen Ensembl |
|
|
CA404644160 rs1599611902 |
799 | Y>H | No |
ClinGen Ensembl |
|
|
CA9283404 rs376663611 |
800 | R>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA9283405 rs751179996 |
800 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1599611941 CA404644230 |
809 | Y>D | No |
ClinGen Ensembl |
|
|
CA306011385 rs939720992 |
810 | R>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs890796074 COSM3822231 CA306011384 |
810 | R>W | Variant assessed as Somatic; impact. breast [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated NCI-TCGA TOPMed |
|
CA404644244 rs1485957925 |
811 | T>I | No |
ClinGen gnomAD |
|
|
CA9283410 rs780084925 |
812 | E>* | No |
ClinGen ExAC gnomAD |
|
|
CA404644246 rs780084925 |
812 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
rs367997445 CA306011391 |
813 | K>E | No |
ClinGen ESP |
|
|
CA404644262 rs1177958785 |
814 | E>A | No |
ClinGen gnomAD |
|
|
rs768533260 CA9283412 |
815 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
CA306011395 rs898266654 |
815 | R>W | No |
ClinGen gnomAD |
|
|
rs1479055287 CA404644270 |
816 | E>K | No |
ClinGen TOPMed gnomAD |
|
|
rs779027108 CA9283413 |
817 | K>R | No |
ClinGen ExAC gnomAD |
|
|
CA306011402 rs918926673 |
820 | C>Y | No |
ClinGen TOPMed gnomAD |
|
|
rs1169156422 CA404644310 |
822 | G>S | No |
ClinGen TOPMed gnomAD |
|
|
CA9283415 rs377517833 |
823 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA306011409 rs377517833 |
823 | R>L | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA404644320 rs1331538532 |
824 | R>G | No |
ClinGen gnomAD |
|
|
rs1438531902 CA404644332 |
825 | E>D | No |
ClinGen gnomAD |
|
|
CA9283416 rs773337506 |
825 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9283417 rs35297167 |
826 | K>N | No |
ClinGen ExAC gnomAD |
|
|
CA404644338 rs1305321836 |
826 | K>R | No |
ClinGen gnomAD |
|
|
CA404644345 rs1213870126 |
827 | G>A | No |
ClinGen TOPMed gnomAD |
|
|
CA404644344 rs1213870126 |
827 | G>D | No |
ClinGen TOPMed gnomAD |
|
| TCGA novel | 828 | S>C | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA9283419 rs777053660 |
829 | D>A | No |
ClinGen ExAC gnomAD |
|
|
rs889070962 CA306011432 |
829 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs889070962 CA404644355 |
829 | D>Y | No |
ClinGen TOPMed gnomAD |
|
|
CA404644377 rs1195947265 |
832 | M>T | No |
ClinGen gnomAD |
|
|
rs1281453720 CA404644388 |
833 | E>D | No |
ClinGen TOPMed |
|
|
rs765584401 CA9283421 |
835 | R>Q | No |
ClinGen ExAC gnomAD |
|
|
rs1222767803 CA404644408 |
837 | K>R | No |
ClinGen TOPMed |
|
|
CA9283423 rs761526908 |
839 | P>S | No |
ClinGen ExAC gnomAD |
|
|
rs1294792584 CA404644426 |
840 | S>G | No |
ClinGen TOPMed |
|
|
rs1294792584 CA404644425 |
840 | S>R | No |
ClinGen TOPMed |
|
|
rs1599613143 CA404644829 |
840 | S>R | No |
ClinGen Ensembl |
|
|
rs758061150 CA9283454 |
841 | E>D | No |
ClinGen ExAC gnomAD |
|
|
CA404644842 rs1599613146 |
842 | V>G | No |
ClinGen Ensembl |
|
|
CA306012093 rs374054984 |
844 | L>P | No |
ClinGen ESP TOPMed |
|
|
CA306012099 rs897927742 |
846 | E>A | No |
ClinGen TOPMed gnomAD |
|
|
CA9283457 rs757373099 |
846 | E>D | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1599613168 CA404644871 |
847 | Y>D | No |
ClinGen Ensembl |
|
|
rs746423564 CA9283459 |
849 | P>L | No |
ClinGen ExAC gnomAD |
|
|
rs267605339 CA306012123 |
850 | A>V | No |
ClinGen Ensembl |
|
|
rs1599613187 CA404644930 |
855 | V>G | No |
ClinGen Ensembl |
|
|
CA306012134 rs1028252104 |
856 | R>Q | No |
ClinGen TOPMed gnomAD |
|
|
CA306012131 rs537427268 COSM1225757 |
856 | R>W | large_intestine [Cosmic] | No |
ClinGen cosmic curated 1000Genomes |
|
rs1250880317 CA404644937 |
857 | S>N | No |
ClinGen TOPMed |
|
| TCGA novel | 857 | S>R | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1335450494 CA404644941 |
857 | S>R | No |
ClinGen TOPMed gnomAD |
|
|
CA404644970 rs1354787940 |
862 | S>T | No |
ClinGen gnomAD |
|
|
rs1599613255 CA404644984 |
864 | D>A | No |
ClinGen Ensembl |
|
|
rs368947489 CA9283465 |
866 | T>M | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs149583340 CA9283467 |
867 | Q>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs1256177669 CA404645011 |
868 | Y>F | No |
ClinGen gnomAD |
|
|
rs1179143880 CA404645034 |
871 | T>N | No |
ClinGen gnomAD |
|
|
rs1599613285 CA404645031 |
871 | T>P | No |
ClinGen Ensembl |
|
| TCGA novel | 871 | T>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA404645038 rs1419259535 |
872 | L>V | No |
ClinGen gnomAD |
|
|
rs1440144163 CA404645045 |
873 | R>H | No |
ClinGen gnomAD |
|
|
CA306012186 rs1020030429 |
894 | A>V | No |
ClinGen TOPMed gnomAD |
|
|
rs756110251 CA9283477 |
895 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 898 | H>Y | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA404645718 rs1599618545 |
899 | H>R | No |
ClinGen Ensembl |
|
|
CA306014272 rs868862486 |
900 | L>I | No |
ClinGen Ensembl |
|
|
rs1467458792 CA404645727 |
901 | V>M | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
rs762395678 CA9283508 |
902 | S>N | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA404645740 rs1384373084 |
903 | D>N | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA9283510 rs139002895 |
904 | D>E | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA404645748 rs1340526880 |
904 | D>N | No |
ClinGen gnomAD |
|
|
CA306014293 rs374239561 |
905 | V>A | No |
ClinGen ESP TOPMed |
|
|
CA404645756 rs143316883 |
905 | V>F | No |
ClinGen ESP ExAC gnomAD |
|
|
CA9283512 rs143316883 |
905 | V>I | No |
ClinGen ESP ExAC gnomAD |
|
|
CA404645839 rs1449211159 |
912 | L>V | No |
ClinGen TOPMed |
|
|
CA9283516 rs368519543 |
914 | L>V | No |
ClinGen ESP ExAC gnomAD |
|
|
CA9283518 rs779593280 |
916 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1246646861 CA404645912 |
918 | K>Q | No |
ClinGen TOPMed |
|
|
rs1424591317 CA404645927 |
919 | R>Q | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
CA9283519 rs753206215 |
919 | R>W | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA gnomAD |
|
rs758880094 CA9283520 |
920 | G>D | No |
ClinGen ExAC gnomAD |
|
|
rs1568428364 CA404645953 |
921 | A>V | No |
ClinGen Ensembl |
|
|
CA306014324 rs920921525 |
922 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
CA404645996 rs1599618680 |
925 | N>T | No |
ClinGen Ensembl |
|
|
rs1299284451 CA404646024 |
927 | S>F | No |
ClinGen TOPMed gnomAD |
|
|
CA404646021 rs1299284451 |
927 | S>Y | No |
ClinGen TOPMed gnomAD |
|
|
CA9283523 rs200429230 |
929 | R>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs779393264 CA9283524 |
929 | R>H | No |
ClinGen ExAC gnomAD |
|
|
CA9283522 rs200429230 |
929 | R>S | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA9283525 rs748832527 |
931 | V>I | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA9283526 rs768108165 |
932 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA9283527 rs550056938 |
932 | R>H | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA9283529 rs771971309 |
933 | A>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
CA404646091 rs1347019392 |
933 | A>V | No |
ClinGen gnomAD |
|
|
CA9283530 rs772869307 |
934 | A>T | No |
ClinGen ExAC gnomAD |
|
|
CA404646105 rs1239232205 |
935 | R>G | No |
ClinGen TOPMed gnomAD |
|
|
CA404646103 rs1239232205 |
935 | R>W | No |
ClinGen TOPMed gnomAD |
|
|
rs1599618741 CA404646134 |
937 | T>P | No |
ClinGen Ensembl |
|
|
rs766513868 CA9283532 |
938 | S>G | No |
ClinGen ExAC gnomAD |
|
|
rs1568428422 CA404646147 |
938 | S>I | No |
ClinGen Ensembl |
|
|
rs1248877011 CA404646174 |
940 | Q>R | No |
ClinGen TOPMed gnomAD |
|
|
CA9283534 rs759709746 |
941 | W>R | No |
ClinGen ExAC gnomAD |
|
|
CA9283535 rs765384492 |
942 | K>M | No |
ClinGen ExAC gnomAD |
|
|
CA9283536 rs753294158 |
945 | R>C | No |
ClinGen ExAC gnomAD |
|
|
rs1433378419 CA404646242 |
945 | R>H | No |
ClinGen TOPMed gnomAD |
|
|
rs758964917 CA9283537 |
946 | C>S | No |
ClinGen ExAC gnomAD |
|
|
rs372429487 CA9283538 |
948 | A>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA9283541 rs779598342 |
949 | D>N | No |
ClinGen ExAC gnomAD |
|
|
rs1448769566 CA404646303 |
950 | E>K | No |
ClinGen gnomAD |
|
| TCGA novel | 954 | K>= | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1599619182 CA404646449 |
955 | V>G | No |
ClinGen Ensembl |
|
|
rs1373242842 CA404646445 |
955 | V>L | No |
ClinGen TOPMed |
|
|
rs762378799 CA9283577 |
956 | M>T | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1230434678 CA404646501 |
959 | Q>R | No |
ClinGen gnomAD |
|
|
rs150661186 CA9283578 |
960 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs150661186 CA306014476 |
960 | R>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs769504888 COSM1225767 CA9283579 |
960 | R>H | Variant assessed as Somatic; 0.0 impact. large_intestine [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA9283580 rs760964368 |
961 | K>E | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs764899629 CA9283581 |
961 | K>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs752342974 CA9283582 |
962 | G>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA404646571 rs777304827 |
965 | I>F | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs777304827 CA9283584 |
965 | I>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs751515274 CA9283585 |
965 | I>M | No |
ClinGen ExAC gnomAD |
|
|
CA404646587 rs1252077676 |
966 | M>T | No |
ClinGen TOPMed |
|
|
rs1055290855 CA306014492 |
966 | M>V | No |
ClinGen TOPMed |
|
|
rs781215770 CA9283587 |
969 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA404646620 rs781215770 |
969 | E>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1156835205 CA404646671 |
973 | T>A | No |
ClinGen gnomAD |
|
|
rs769666253 CA9283589 |
974 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
CA404646717 rs1312326153 |
976 | A>V | No |
ClinGen gnomAD |
|
|
rs1338946957 CA404646741 |
978 | T>M | No |
ClinGen TOPMed gnomAD |
|
|
rs749499866 CA9283591 |
979 | E>A | No |
ClinGen ExAC gnomAD |
|
|
rs1238414185 CA404646777 |
981 | P>A | No |
ClinGen TOPMed gnomAD |
|
|
rs1238414185 CA404646779 |
981 | P>S | No |
ClinGen TOPMed gnomAD |
|
|
CA306014516 CA404646785 rs202214267 |
982 | V>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA9283593 rs202214267 |
982 | V>M | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA404646807 rs1254811155 |
984 | V>I | No |
ClinGen gnomAD |
|
|
CA404646825 rs1173958965 |
985 | Q>R | No |
ClinGen TOPMed |
|
|
rs1440843435 CA404646952 |
986 | H>Y | No |
ClinGen gnomAD |
|
|
CA9283611 rs768936961 |
988 | A>V | No |
ClinGen ExAC gnomAD |
|
|
CA404646970 rs1333298965 |
989 | R>Q | No |
ClinGen TOPMed gnomAD |
|
|
rs1478069292 CA404646969 |
989 | R>W | No |
ClinGen TOPMed gnomAD |
|
|
rs772089041 CA9283614 |
991 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 992 | E>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs1316953951 CA404647010 |
995 | V>M | No |
ClinGen gnomAD |
|
|
rs1599620121 CA404647032 |
998 | E>G | No |
ClinGen Ensembl |
|
|
rs1458091659 CA404647028 |
998 | E>K | No |
ClinGen gnomAD |
|
|
CA9283617 rs771351095 |
999 | G>V | No |
ClinGen ExAC gnomAD |
|
|
CA9283618 rs566655086 |
1000 | A>T | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA9283619 rs140209091 |
1000 | A>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA404647048 rs1334490123 |
1001 | S>Y | No |
ClinGen TOPMed |
|
|
CA9283621 rs201028029 |
1002 | S>I | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA9283622 rs144154968 |
1002 | S>R | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA306014965 rs201028029 |
1002 | S>T | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA9283623 rs372700335 |
1003 | S>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA404647060 rs372700335 |
1003 | S>W | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA404647080 rs1393540351 |
1006 | E>D | No |
ClinGen TOPMed gnomAD |
|
|
rs756111329 CA9283625 |
1007 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs753671585 CA9283627 |
1008 | F>C | No |
ClinGen ExAC gnomAD |
|
|
rs766170546 CA9283626 |
1008 | F>V | No |
ClinGen ExAC gnomAD |
|
|
rs1363468693 CA404647093 |
1009 | L>V | No |
ClinGen TOPMed |
|
|
rs1318130401 CA404647116 |
1012 | P>L | No |
ClinGen gnomAD |
|
|
CA404647134 rs1489443063 |
1015 | L>P | No |
ClinGen gnomAD |
|
|
CA9283630 rs748346299 |
1016 | Q>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA |
|
CA306015175 rs372160193 |
1020 | K>R | No |
ClinGen ESP TOPMed gnomAD |
|
|
CA9283646 rs530799566 |
1022 | F>I | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1599620579 CA404647193 |
1022 | F>S | No |
ClinGen Ensembl |
|
|
CA306015177 rs530799566 |
1022 | F>V | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs182647749 CA9283647 |
1023 | R>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs376755146 CA9283648 |
1023 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs370020528 CA9283650 |
1024 | R>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA9283651 rs777910155 |
1024 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs370020528 CA306015188 |
1024 | R>S | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA9283653 rs757242128 |
1025 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs747092602 CA9283652 |
1025 | R>W | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA306015200 rs867206726 |
1026 | W>* | No |
ClinGen Ensembl |
|
|
CA306015202 rs781732016 |
1028 | S>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9283656 rs746333267 |
1029 | E>K | No |
ClinGen ExAC gnomAD |
|
|
CA9283655 rs746333267 |
1029 | E>Q | No |
ClinGen ExAC gnomAD |
|
|
CA9283658 rs749616440 |
1031 | A>S | No |
ClinGen ExAC gnomAD |
|
|
CA306015218 rs952111197 |
1031 | A>V | No |
ClinGen gnomAD |
|
|
CA404647249 rs1322570578 |
1032 | R>Q | No |
ClinGen TOPMed |
|
|
CA9283660 COSM992603 rs772960055 |
1032 | R>W | Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic] | No |
ClinGen cosmic curated ExAC NCI-TCGA gnomAD |
|
CA9283662 COSM1225762 rs200337811 |
1035 | R>C | large_intestine [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC TOPMed gnomAD |
|
rs776669770 CA9283663 |
1035 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs776669770 CA404647265 |
1035 | R>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs375234398 CA9283666 |
1036 | G>D | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA9283665 rs765138509 |
1036 | G>S | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs375234398 CA404647270 |
1036 | G>V | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
COSM126179 CA9283667 rs762666436 |
1038 | A>V | upper_aerodigestive_tract [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
rs1420961000 CA404647294 |
1040 | S>N | No |
ClinGen TOPMed gnomAD |
|
|
rs904804263 CA306015234 |
1042 | W>L | No |
ClinGen TOPMed |
|
|
rs751729564 CA404647323 |
1044 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs751729564 CA9283669 |
1044 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs764327319 CA9283668 |
1044 | R>W | No |
ClinGen ExAC gnomAD |
|
|
rs201497679 CA9283670 |
1046 | V>G | No |
ClinGen ExAC gnomAD |
|
|
rs1199662315 CA404647340 |
1048 | V>M | No |
ClinGen TOPMed gnomAD |
|
|
CA9283675 rs780641130 |
1050 | S>R | No |
ClinGen ExAC gnomAD |
|
|
CA404647363 rs1487761010 |
1051 | A>S | Variant assessed as Somatic; impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA TOPMed gnomAD |
|
CA404647361 rs1487761010 |
1051 | A>T | No |
ClinGen TOPMed gnomAD |
|
|
rs372894104 CA9283677 |
1053 | D>N | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
rs200083712 CA9283679 |
1054 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs775990000 CA9283680 |
1055 | D>N | No |
ClinGen ExAC gnomAD |
|
|
rs1354555594 CA404647404 |
1057 | R>C | No |
ClinGen TOPMed gnomAD |
|
|
rs759029016 CA9283681 |
1057 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA306015263 rs924332898 |
1059 | K>E | No |
ClinGen Ensembl |
|
|
rs775363290 CA9283683 |
1060 | L>P | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs775363290 CA9283684 |
1060 | L>R | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs763852481 CA9283685 |
1061 | S>G | No |
ClinGen ExAC gnomAD |
|
|
CA404647428 rs1295368533 |
1061 | S>N | No |
ClinGen gnomAD |
|
|
rs373249091 CA9283687 |
1065 | M>I | No |
ClinGen ESP ExAC gnomAD |
|
|
CA404647480 rs1215579161 |
1068 | I>T | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen NCI-TCGA gnomAD |
|
rs750477702 CA9283689 |
1068 | I>V | No |
ClinGen ExAC gnomAD |
|
|
CA9283690 rs756179341 |
1069 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA306015295 rs1054174019 |
1071 | S>C | No |
ClinGen Ensembl |
|
|
rs943224298 CA306015303 |
1072 | E>D | No |
ClinGen Ensembl |
|
|
CA9283692 rs138372644 |
1072 | E>K | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD |
|
rs755435506 CA9283693 |
1075 | M>V | No |
ClinGen ExAC gnomAD |
|
|
rs980885534 CA306015314 |
1077 | R>C | No |
ClinGen TOPMed gnomAD |
|
|
CA9283694 rs375962555 |
1077 | R>H | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
CA9283695 rs558015742 |
1078 | R>C | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
rs756872370 CA9283696 |
1078 | R>H | No |
ClinGen ExAC gnomAD |
|
|
rs745396422 CA9283698 |
1080 | T>P | No |
ClinGen ExAC gnomAD |
|
|
rs749189612 CA9283701 |
1083 | R>Q | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs775453054 COSM1225756 CA9283700 |
1083 | R>W | large_intestine [Cosmic] | No |
ClinGen cosmic curated ExAC gnomAD |
|
CA404647628 rs1376818152 |
1089 | P>H | No |
ClinGen gnomAD |
|
|
CA404647625 rs1316098770 |
1089 | P>S | No |
ClinGen TOPMed gnomAD |
|
|
CA404647638 rs748740998 |
1091 | V>A | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA404647636 rs1238560162 |
1091 | V>F | No |
ClinGen gnomAD |
|
|
CA9283719 rs748740998 |
1091 | V>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs989844213 CA306015407 |
1092 | L>V | No |
ClinGen Ensembl |
|
|
rs747918923 CA9283722 |
1094 | R>C | No |
ClinGen ExAC gnomAD |
|
|
rs771879389 CA9283723 |
1094 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs771879389 CA404647651 |
1094 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1439037670 CA404647670 |
1097 | Q>E | No |
ClinGen gnomAD |
|
|
rs773347645 CA9283724 |
1097 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
rs1382064223 CA404647676 |
1098 | H>N | No |
ClinGen gnomAD |
|
|
CA404647692 rs1172056884 |
1100 | E>K | No |
ClinGen gnomAD |
|
|
CA9283726 rs766622972 |
1101 | E>G | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA404647700 rs1236580013 |
1101 | E>K | No |
ClinGen TOPMed |
|
| TCGA novel | 1102 | W>* | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
CA404647718 rs1416318230 |
1103 | H>Y | No |
ClinGen gnomAD |
|
|
rs374200808 CA9283727 |
1105 | R>C | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9283728 rs141001345 |
1105 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA404647762 rs1599621066 |
1109 | D>V | No |
ClinGen Ensembl |
|
|
rs753195155 CA9283730 |
1109 | D>Y | No |
ClinGen ExAC TOPMed gnomAD |
|
| TCGA novel | 1110 | N>D | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs763273012 CA9283731 |
1110 | N>S | No |
ClinGen ExAC gnomAD |
|
|
CA9283733 rs574039900 |
1112 | T>M | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA9283734 rs755779360 |
1115 | A>V | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs753381939 CA404647806 |
1116 | A>G | No |
ClinGen ExAC gnomAD |
|
|
CA9283736 rs753381939 |
1116 | A>V | No |
ClinGen ExAC gnomAD |
|
|
rs1198254698 CA404647821 |
1119 | V>L | No |
ClinGen gnomAD |
|
|
CA9283737 rs754435536 |
1120 | Q>R | No |
ClinGen ExAC gnomAD |
|
|
rs561893074 CA9283738 |
1121 | D>E | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
rs1456304662 CA404647835 |
1121 | D>Y | No |
ClinGen TOPMed gnomAD |
|
|
rs771831645 CA404647860 CA9283740 |
1124 | M>I | No |
ClinGen ExAC gnomAD |
|
|
rs199950391 CA306015448 |
1124 | M>L | No |
ClinGen 1000Genomes gnomAD |
|
|
rs1241860332 CA404647877 |
1127 | E>* | No |
ClinGen TOPMed |
|
|
rs777608389 CA9283741 |
1128 | D>N | No |
ClinGen ExAC gnomAD |
|
|
CA9283742 rs746740920 |
1129 | E>K | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs1269622775 CA404647902 |
1130 | D>G | No |
ClinGen TOPMed |
|
| TCGA novel | 1131 | M>I | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs771282789 CA404647906 |
1131 | M>L | No |
ClinGen ExAC gnomAD |
|
|
CA9283743 rs771282789 |
1131 | M>V | No |
ClinGen ExAC gnomAD |
|
| TCGA novel | 1132 | V>A | Variant assessed as Somatic; impact. [NCI-TCGA] | No | NCI-TCGA |
|
rs550835219 CA9283744 |
1132 | V>I | No |
ClinGen 1000Genomes ExAC gnomAD |
|
|
CA9283745 rs759707633 |
1133 | P>S | No |
ClinGen ExAC gnomAD |
|
|
CA9283746 rs150206415 |
1136 | T>M | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
rs904976166 CA306015479 |
1138 | C>S | No |
ClinGen TOPMed |
|
|
CA9283747 rs775898027 |
1139 | E>V | No |
ClinGen ExAC gnomAD |
|
|
rs1209115050 CA404647971 |
1141 | V>L | No |
ClinGen gnomAD |
|
|
rs201269792 CA306015487 |
1143 | V>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
rs201269792 CA9283749 |
1143 | V>M | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA306015494 rs201105429 |
1144 | H>Y | No |
ClinGen gnomAD |
|
|
rs1172989901 CA404647995 |
1145 | G>C | No |
ClinGen gnomAD |
|
|
CA404647997 rs1373951064 |
1145 | G>D | No |
ClinGen gnomAD |
|
|
rs1172989901 CA404647996 |
1145 | G>S | No |
ClinGen gnomAD |
|
|
CA9283754 rs533266936 COSM992605 |
1148 | V>M | endometrium [Cosmic] | No |
ClinGen cosmic curated 1000Genomes ExAC gnomAD |
|
rs1393515518 CA404648020 |
1149 | T>I | No |
ClinGen gnomAD |
|
|
rs546578699 CA9283755 |
1150 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen 1000Genomes ExAC NCI-TCGA gnomAD |
|
rs376255592 CA9283756 |
1150 | R>H | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9283758 rs376892309 |
1152 | R>C | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA9283759 rs566955025 |
1152 | R>H | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA404648036 rs566955025 |
1152 | R>P | No |
ClinGen 1000Genomes ExAC TOPMed gnomAD |
|
|
CA9283760 rs746830706 |
1153 | V>M | No |
ClinGen ExAC gnomAD |
|
|
CA404648050 rs1243756239 |
1154 | Q>H | No |
ClinGen gnomAD |
|
|
CA9283761 rs139041823 |
1157 | R>C | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD |
|
CA9283762 rs139041823 |
1157 | R>G | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
CA9283763 rs143041673 |
1157 | R>H | No |
ClinGen ESP ExAC TOPMed gnomAD |
|
|
COSM1712006 CA9283764 rs769827934 |
1158 | R>C | skin [Cosmic] | No |
ClinGen cosmic curated ExAC TOPMed gnomAD |
|
CA9283765 rs775623591 |
1158 | R>H | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs775623591 CA404648073 |
1158 | R>L | No |
ClinGen ExAC TOPMed gnomAD |
|
|
CA9283766 rs762876758 |
1159 | P>L | Variant assessed as Somatic; 0.0 impact. [NCI-TCGA] | No |
ClinGen ExAC NCI-TCGA TOPMed gnomAD |
|
rs1224398252 CA404648080 |
1160 | A>P | No |
ClinGen TOPMed |
|
|
CA9283769 rs79625040 |
1161 | S>L | No |
ClinGen 1000Genomes ESP ExAC TOPMed gnomAD |
|
|
rs1344228817 CA404648094 |
1162 | P>H | No |
ClinGen TOPMed |
No associated diseases with O75182
5 regional properties for O75182
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | Paired amphipathic helix | 37 - 107 | IPR003822-1 |
| repeat | Paired amphipathic helix | 153 - 238 | IPR003822-2 |
| repeat | Paired amphipathic helix | 292 - 369 | IPR003822-3 |
| domain | Histone deacetylase interacting domain | 393 - 525 | IPR013194 |
| domain | Sin3, C-terminal | 775 - 1075 | IPR031693 |
10 GO annotations of cellular component
| Name | Definition |
|---|---|
| autosome | Any chromosome other than a sex chromosome. |
| chromatin | The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. |
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| histone deacetylase complex | A protein complex that possesses histone deacetylase activity. |
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| Sin3 complex | A multiprotein complex that functions broadly in eukaryotic organisms as a transcriptional repressor of protein-coding genes, through the gene-specific deacetylation of histones. Amongst its subunits, the Sin3 complex contains Sin3-like proteins, and a number of core proteins that are shared with the NuRD complex (including histone deacetylases and histone binding proteins). The Sin3 complex does not directly bind DNA itself, but is targeted to specific genes through protein-protein interactions with DNA-binding proteins. |
| X chromosome | The sex chromosome present in both sexes of species in which the male is the heterogametic sex. Two copies of the X chromosome are present in each somatic cell of females and one copy is present in males. |
| XY body | A structure found in a male mammalian spermatocyte containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery. |
| Y chromosome | The sex chromosome present in males of species in which the male is the heterogametic sex; generally, the sex chromosome that pairs with the X chromosome in the heterogametic sex. The Y chromosome is absent from the cells of females and present in one copy in the somatic cells of males. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| chromatin binding | Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. |
| transcription corepressor activity | A transcription coregulator activity that represses or decreases the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription corepressors modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| histone deacetylation | The modification of histones by removal of acetyl groups. |
| negative regulation of cell migration | Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration. |
| negative regulation of transcription by RNA polymerase II | Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II. |
4 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q96ST3 | SIN3A | Paired amphipathic helix protein Sin3a | Homo sapiens (Human) | PR |
| Q60520 | Sin3a | Paired amphipathic helix protein Sin3a | Mus musculus (Mouse) | PR |
| Q62141 | Sin3b | Paired amphipathic helix protein Sin3b | Mus musculus (Mouse) | PR |
| Q9XIK6 | SNL6 | Paired amphipathic helix protein Sin3-like 6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAHAGGGSGG | SGAGGPAGRG | LSGARWGRSG | SAGHEKLPVH | VEDALTYLDQ | VKIRFGSDPA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TYNGFLEIMK | EFKSQSIDTP | GVIRRVSQLF | HEHPDLIVGF | NAFLPLGYRI | DIPKNGKLNI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QSPLTSQENS | HNHGDGAEDF | KQQVPYKEDK | PQVPLESDSV | EFNNAISYVN | KIKTRFLDHP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EIYRSFLEIL | HTYQKEQLNT | RGRPFRGMSE | EEVFTEVANL | FRGQEDLLSE | FGQFLPEAKR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SLFTGNGPCE | MHSVQKNEHD | KTPEHSRKRS | RPSLLRPVSA | PAKKKMKLRG | TKDLSIAAVG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KYGTLQEFSF | FDKVRRVLKS | QEVYENFLRC | IALFNQELVS | GSELLQLVSP | FLGKFPELFA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| QFKSFLGVKE | LSFAPPMSDR | SGDGISREID | YASCKRIGSS | YRALPKTYQQ | PKCSGRTAIC |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KELDHWTLLQ | GSWTDDYCMS | KFKNTCWIPG | YSAGVLNDTW | VSFPSWSEDS | TFVSSKKTPY |
| 490 | 500 | 510 | 520 | 530 | 540 |
| EEQLHRCEDE | RFELDVVLET | NLATIRVLES | VQKKLSRMAP | EDQEKFRLDD | SLGGTSEVIQ |
| 550 | 560 | 570 | 580 | 590 | 600 |
| RRAIYRIYGD | KAPEIIESLK | KNPVTAVPVV | LKRLKAKEEE | WREAQQGFNK | IWREQYEKAY |
| 610 | 620 | 630 | 640 | 650 | 660 |
| LKSLDHQAVN | FKQNDTKALR | SKSLLNEIES | VYDEHQEQHS | EGRSAPSSEP | HLIFVYEDRQ |
| 670 | 680 | 690 | 700 | 710 | 720 |
| ILEDAAALIS | YYVKRQPAIQ | KEDQGTIHQL | LHQFVPSLFF | SQQLDLGASE | ESADEDRDSP |
| 730 | 740 | 750 | 760 | 770 | 780 |
| QGQTTDPSER | KKPAPGPHSS | PPEEKGAFGD | APATEQPPLP | PPAPHKPLDD | VYSLFFANNN |
| 790 | 800 | 810 | 820 | 830 | 840 |
| WYFFLRLHQT | LCSRLLKIYR | QAQKQLLEYR | TEKEREKLLC | EGRREKGSDP | AMELRLKQPS |
| 850 | 860 | 870 | 880 | 890 | 900 |
| EVELEEYYPA | FLDMVRSLLE | GSIDPTQYED | TLREMFTIHA | YVGFTMDKLV | QNIARQLHHL |
| 910 | 920 | 930 | 940 | 950 | 960 |
| VSDDVCLKVV | ELYLNEKKRG | AAGGNLSSRC | VRAARETSYQ | WKAERCMADE | NCFKVMFLQR |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| KGQVIMTIEL | LDTEEAQTED | PVEVQHLARY | VEQYVGTEGA | SSSPTEGFLL | KPVFLQRNLK |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| KFRRRWQSEQ | ARALRGEARS | SWKRLVGVES | ACDVDCRFKL | STHKMVFIVN | SEDYMYRRGT |
| 1090 | 1100 | 1110 | 1120 | 1130 | 1140 |
| LCRAKQVQPL | VLLRHHQHFE | EWHSRWLEDN | VTVEAASLVQ | DWLMGEEDED | MVPCKTLCET |
| 1150 | 1160 | ||||
| VHVHGLPVTR | YRVQYSRRPA | SP |