Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for A6QPI4

Entry ID Method Resolution Chain Position Source
AF-A6QPI4-F1 Predicted AlphaFoldDB

67 variants for A6QPI4

Variant ID(s) Position Change Description Diseaes Association Provenance
rs135968429 16 I>L No EVA
rs479094930 32 V>G No EVA
rs447690213 34 S>P No EVA
rs464476709 35 L>R No EVA
rs133939369 36 W>G No EVA
rs133939369 36 W>R No EVA
rs450263991 37 P>R No EVA
rs435779687 38 R>P No EVA
rs465709789 40 H>L No EVA
rs434401747 40 H>Q No EVA
rs443199371 42 Q>H No EVA
rs471338581 42 Q>P No EVA
rs457203304 43 Y>N No EVA
rs474120066 43 Y>S No EVA
rs442682643 44 S>A No EVA
rs442682643 44 S>P No EVA
rs459498730 45 C>S No EVA
rs458158513 47 G>E No EVA
rs441311834 47 G>W No EVA
rs136574341 48 S>C No EVA
rs136574341 48 S>G No EVA
rs450046032 48 S>R No EVA
rs480682087 50 G>A No EVA
rs470512626 50 G>R No EVA
rs466176451 51 S>G No EVA
rs434465106 51 S>N No EVA
rs451329902 51 S>R No EVA
rs466176451 51 S>R No EVA
rs434465106 51 S>T No EVA
rs465048519 52 S>A No EVA
rs436828710 52 S>L No EVA
rs465048519 52 S>P No EVA
rs474115096 53 E>A No EVA
rs442695137 53 E>D No EVA
rs474115096 53 E>G No EVA
rs474115096 53 E>V No EVA
rs453147636 54 P>A No EVA
rs473158394 54 P>H No EVA
rs453147636 54 P>T No EVA
rs458196687 55 P>R No EVA
rs443608501 56 G>R No EVA
rs480743316 57 S>F No EVA
rs480743316 57 S>Y No EVA
rs459863567 58 A>P No EVA
rs459863567 58 A>S No EVA
rs467711625 77 I>T No EVA
rs436408851 78 L>R No EVA
rs473397886 81 T>P No EVA
rs438771915 85 K>N No EVA
rs476103751 86 A>G No EVA
rs452803061 86 A>S No EVA
rs444686964 94 I>V No EVA
rs469478786 103 R>G No EVA
rs380050463 103 R>S No EVA
rs468877191 119 I>M No EVA
rs448479244 119 I>N No EVA
rs434217110 120 I>F No EVA
rs454329305 121 A>G No EVA
rs464693466 124 A>S No EVA
rs433356085 125 V>A No EVA
rs456197791 127 A>S No EVA
rs443597057 143 N>K No EVA
rs457126177 144 L>P No EVA
rs474329070 148 A>E No EVA
rs443045830 149 K>R No EVA
rs459980611 150 W>R No EVA
rs438983058 158 A>G No EVA

No associated diseases with A6QPI4

No regional properties for A6QPI4

Type Name Position InterPro Accession
No domain, repeats, and functional sites for A6QPI4

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

4 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5T6X4 FAM162B Protein FAM162B Homo sapiens (Human) PR
Q96A26 FAM162A Protein FAM162A Homo sapiens (Human) PR
Q9CX19 Fam162b Protein FAM162B Mus musculus (Mouse) PR
Q9D6U8 Fam162a Protein FAM162A Mus musculus (Mouse) PR
10 20 30 40 50 60
MLATVGSLLR LRLGRIPCCA PGAPPEVERR PVASLWPRGH PQYSCGGSPG SSEPPGSAEK
70 80 90 100 110 120
VHRVPAEHKP SQFDKRILLW TGRFKAMEDI PPRIPPEMID AARNKARVKA CYIMIGLTII
130 140 150 160
ACFAVIASAK RAAERHESLT SWNLAKKAKW REEAALAAQA KAK