Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

6 structures for Q9ZVL3

Entry ID Method Resolution Chain Position Source
5G49 X-ray 230 A B 55-148 PDB
6R0M X-ray 230 A B/D 55-148 PDB
6R0N X-ray 210 A B 55-148 PDB
6R2V X-ray 250 A C 55-148 PDB
7CVQ X-ray 330 A A/F/K/P 55-148 PDB
AF-Q9ZVL3-F1 Predicted AlphaFoldDB

12 variants for Q9ZVL3

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_1_20451679_A_G 3 Q>R No 1000Genomes
tmp_1_20451750_A_G 27 T>A No 1000Genomes
ENSVATH04963594 131 A>T No 1000Genomes
tmp_1_20452072_C_T 134 T>I No 1000Genomes
tmp_1_20452146_G_C 159 V>L No 1000Genomes
tmp_1_20452179_C_A 170 P>T No 1000Genomes
ENSVATH04963596 176 P>S No 1000Genomes
ENSVATH04963597 188 M>L No 1000Genomes
tmp_1_20452234_T_G 188 M>R No 1000Genomes
tmp_1_20452249_C_T 193 A>V No 1000Genomes
tmp_1_20452255_C_T 195 P>L No 1000Genomes
ENSVATH04963598 204 M>I No 1000Genomes

No associated diseases with Q9ZVL3

1 regional properties for Q9ZVL3

Type Name Position InterPro Accession
domain Histone H2A/H2B/H3 32 - 133 IPR007125

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

5 GO annotations of molecular function

Name Definition
DNA-binding transcription activator activity, RNA polymerase II-specific A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets transcribed by RNA polymerase II.
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
protein heterodimerization activity Binding to a nonidentical protein to form a heterodimer.
transcription cis-regulatory region binding Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
transcription coregulator activity A transcription regulator activity that modulates the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators.

6 GO annotations of biological process

Name Definition
abscisic acid-activated signaling pathway The series of molecular signals generated by the binding of the plant hormone abscisic acid (ABA) to a receptor, and ending with modulation of a cellular process, e.g. transcription.
gibberellic acid mediated signaling pathway The series of molecular signals mediated by the detection of gibberellic acid.
long-day photoperiodism, flowering A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light that exceeds the critical day length. The critical day length varies between species. Although the term is long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 minus the critical day length.
positive regulation of photomorphogenesis Any process that activates or increases the frequency, rate or extent of photomorphogenesis.
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
regulation of seed germination Any process that modulates the frequency, rate or extent of seed germination.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8L4B2 NFYC9 Nuclear transcription factor Y subunit C-9 Arabidopsis thaliana (Mouse-ear cress) PR
Q8LCG7 NFYC2 Nuclear transcription factor Y subunit C-2 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MDQQGQSSAM NYGSNPYQTN AMTTTPTGSD HPAYHQIHQQ QQQQLTQQLQ SFWETQFKEI
70 80 90 100 110 120
EKTTDFKNHS LPLARIKKIM KADEDVRMIS AEAPVVFARA CEMFILELTL RSWNHTEENK
130 140 150 160 170 180
RRTLQKNDIA AAVTRTDIFD FLVDIVPRED LRDEVLGGVG AEAATAAGYP YGYLPPGTAP
190 200 210
IGNPGMVMGN PGAYPPNPYM GQPMWQQPGP EQQDPDN