Q9ZPY1
Gene name |
PPOX2 (At2g46580, F13A10.11) |
Protein name |
Pyridoxine/pyridoxamine 5'-phosphate oxidase 2 |
Names |
AtPPOX1 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G46580 |
EC number |
1.4.3.5: With oxygen as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9ZPY1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9ZPY1-F1 | Predicted | AlphaFoldDB |
17 variants for Q9ZPY1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH05729438 | 3 | T>I | No | 1000Genomes | |
| ENSVATH01994880 | 14 | G>A | No | 1000Genomes | |
| ENSVATH00801194 | 18 | A>V | No | 1000Genomes | |
| tmp_2_19130338_T_A | 32 | T>S | No | 1000Genomes | |
| tmp_2_19130296_A_C | 46 | F>V | No | 1000Genomes | |
| tmp_2_19130205_C_T | 54 | D>N | No | 1000Genomes | |
| ENSVATH05729435 | 62 | L>H | No | 1000Genomes | |
| tmp_2_19129936_C_A | 86 | W>L | No | 1000Genomes | |
| tmp_2_19129886_G_T | 103 | P>T | No | 1000Genomes | |
| ENSVATH13657319 | 123 | R>M | No | 1000Genomes | |
| tmp_2_19129731_A_C | 125 | I>S | No | 1000Genomes | |
| tmp_2_19129684_T_G | 141 | S>R | No | 1000Genomes | |
| ENSVATH05729430 | 149 | S>L | No | 1000Genomes | |
| ENSVATH13657316 | 167 | D>Y | No | 1000Genomes | |
| ENSVATH13657315 | 173 | T>S | No | 1000Genomes | |
| ENSVATH14621478 | 191 | W>R | No | 1000Genomes | |
| ENSVATH05729426 | 196 | V>I | No | 1000Genomes |
No associated diseases with Q9ZPY1
1 regional properties for Q9ZPY1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Pyridoxamine 5'-phosphate oxidase, Alr4036 family, FMN-binding domain | 6 - 98 | IPR024624 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.4.3.5 | With oxygen as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| FMN binding | Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. |
| pyridoxamine-phosphate oxidase activity | Catalysis of the reaction: pyridoxamine 5'-phosphate + H2O + O2 = pyridoxal 5'-phosphate + NH3 + hydrogen peroxide. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| pyridoxal 5'-phosphate salvage | Any process that generates pyridoxal 5'-phosphate, the active form of vitamin B6, from derivatives of it without de novo synthesis. |
| pyridoxine biosynthetic process | The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds. |
3 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| P38075 | PDX3 | Pyridoxamine 5'-phosphate oxidase | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | PR |
| Q5E9K3 | PNPO | Pyridoxine-5'-phosphate oxidase | Bos taurus (Bovine) | PR |
| Q9NVS9 | PNPO | Pyridoxine-5'-phosphate oxidase | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGTHVAPWKQ | LLFGAIEANS | HLSHSSYVQL | ATIGLNGRPS | NRTVVFRGFE | ENSDRIQINT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DLRSRKIEEL | KHCPFSEMCW | YFSDTWEQFR | INGRIEVIDA | SNPDQTKLQQ | REKAWFANSL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RSRLIYVCPT | PGSPCNSEQS | SQQVKLDPSS | GPVPEYCLLL | LEPEKVDYLN | LKTNQRLFFS |
| 190 | |||||
| SMATGTGEKC | WTSEKVNP |