Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9XED8

Entry ID Method Resolution Chain Position Source
AF-Q9XED8-F1 Predicted AlphaFoldDB

48 variants for Q9XED8

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH06764047 16 L>V No 1000Genomes
tmp_4_12451927_G_T 55 K>N No 1000Genomes
ENSVATH14289635 91 V>F No 1000Genomes
tmp_4_12452345_C_T 106 P>L No 1000Genomes
ENSVATH02917937 110 R>M No 1000Genomes
tmp_4_12452583_G_A 158 A>T No 1000Genomes
ENSVATH06764059 159 E>V No 1000Genomes
tmp_4_12452789_A_T 198 D>V No 1000Genomes
tmp_4_12452807_G_T 204 R>I No 1000Genomes
ENSVATH06764072 208 G>R No 1000Genomes
ENSVATH14289637 216 R>H No 1000Genomes
tmp_4_12452935_C_T 217 A>V No 1000Genomes
ENSVATH00534463 219 L>R No 1000Genomes
ENSVATH14289638 235 H>Y No 1000Genomes
ENSVATH06764083 266 S>N No 1000Genomes
tmp_4_12453220_A_C 285 K>Q No 1000Genomes
tmp_4_12453233_A_T 289 E>V No 1000Genomes
ENSVATH12187978 290 G>E No 1000Genomes
tmp_4_12453348_C_T 301 T>M No 1000Genomes
tmp_4_12453375_C_T 310 P>L No 1000Genomes
tmp_4_12453392_A_C 316 K>Q No 1000Genomes
ENSVATH06764088 327 P>L No 1000Genomes
ENSVATH00534471 329 S>T No 1000Genomes
ENSVATH00534472 330 I>T No 1000Genomes
ENSVATH06764089 341 I>T No 1000Genomes
ENSVATH00534474 346 N>S No 1000Genomes
ENSVATH00534475 350 V>I No 1000Genomes
tmp_4_12453610_C_T 361 P>S No 1000Genomes
ENSVATH06764092 363 Q>P No 1000Genomes
tmp_4_12453855_C_T 416 S>F No 1000Genomes
ENSVATH06764098 439 V>I No 1000Genomes
ENSVATH12187980 447 P>H No 1000Genomes
ENSVATH02917941 462 S>C No 1000Genomes
tmp_4_12454020_A_C 471 K>T No 1000Genomes
tmp_4_12454031_A_C 475 M>L No 1000Genomes
tmp_4_12454070_C_A 488 H>N No 1000Genomes
tmp_4_12454116_A_G 503 K>R No 1000Genomes
ENSVATH06764101 507 A>V No 1000Genomes
ENSVATH00534481 542 N>T No 1000Genomes
tmp_4_12454391_T_C 551 I>T No 1000Genomes
ENSVATH06764106 565 R>Q No 1000Genomes
ENSVATH06764107 566 S>N No 1000Genomes
tmp_4_12454439_G_C 567 R>P No 1000Genomes
ENSVATH12188075 607 V>M No 1000Genomes
tmp_4_12454642_A_G 608 K>E No 1000Genomes
ENSVATH06764109 611 T>M No 1000Genomes
tmp_4_12454680_A_T 620 L>F No 1000Genomes
ENSVATH06764110 630 T>I No 1000Genomes

No associated diseases with Q9XED8

1 regional properties for Q9XED8

Type Name Position InterPro Accession
domain GPCR, rhodopsin-like, 7TM 50 - 302 IPR017452

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
transcription cis-regulatory region binding Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.

1 GO annotations of biological process

Name Definition
auxin-activated signaling pathway The series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9SKN5 ARF10 Auxin response factor 10 Arabidopsis thaliana (Mouse-ear cress) PR
Q9FX25 ARF13 Auxin response factor 13 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MANRGGEYLY DELWKLCAGP LVDVPQAQER VYYFPQGHME QLEASTQQVD LNTMKPLFVL
70 80 90 100 110 120
PPKILCNVMN VSLQAEKDTD EVYAQITLIP VGTEVDEPMS PDPSPPELQR PKVHSFSKVL
130 140 150 160 170 180
TASDTSTHGG FSVLRKHATE CLPPLDMTQQ TPTQELVAED VHGYQWKFKH IFRGQPRRHL
190 200 210 220 230 240
LTTGWSTFVT SKRLVAGDTF VFLRGENGEL RVGVRRANLQ QSSMPSSVIS SHSMHLGVLA
250 260 270 280 290 300
TARHATQTKT MFIVYYKPRT SQFIISLNKY LEAMSNKFSV GMRFKMRFEG EDSPERRYSG
310 320 330 340 350 360
TVIGVKDCSP HWKDSKWRCL EVHWDEPASI SRPNKVSPWE IEPFVNSENV PKSVMLKNKR
370 380 390 400 410 420
PRQVSEVSAL DVGITASNLW SSVLTQPHEF AQSCITSQWS SPQQCHRDAN EDAKKSDWLN
430 440 450 460 470 480
NSYSVSNVAK DSTLNDQMVS PVEQKKPETT ANYRLFGIDL MSSSLAVPEE KTAPMRPINI
490 500 510 520 530 540
SKPTMDSHSD PKSEISKVSE EKKQEPAEGS PKEVQSKQSS STRSRTKVQM QGVPVGRAVD
550 560 570 580 590 600
LNALKGYNEL IDDIEKLFDI KGELRSRNQW EIVFTDDEGD MMLVGDDPWP EFCNMVKRIF
610 620 630
IWSKEEVKKM TPGNQLRMLL REVETTLTTT SKTDNHSN