Q9W1A2

PR
Gene name
Naa35
Protein name
N-alpha-acetyltransferase 35, NatC auxiliary subunit homolog
Names
Embryonic growth-associated protein homolog, Protein MAK10 homolog
Species
Drosophila melanogaster (Fruit fly)
KEGG Pathway
dme:Dmel_CG4065
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-91 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9W1A2

Entry ID Method Resolution Chain Position Source
AF-Q9W1A2-F1 Predicted AlphaFoldDB

No variants for Q9W1A2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9W1A2

No associated diseases with Q9W1A2

No regional properties for Q9W1A2

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9W1A2

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
NatC complex A conserved complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule that has a Met-Ile, Met-Leu, Met-Trp, or Met-Phe N-terminus. In Saccharomyces the complex includes Mak3p, Mak10p, and Mak31p.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
N-terminal peptidyl-methionine acetylation The acetylation of the N-terminal methionine of proteins to form the derivative N-acetyl-L-methionine.
N-terminal protein amino acid acetylation The acetylation of the N-terminal amino acid of proteins.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q02197 MAK10 N-alpha-acetyltransferase 35, NatC auxiliary subunit Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q5VZE5 NAA35 N-alpha-acetyltransferase 35, NatC auxiliary subunit Homo sapiens (Human) PR
10 20 30 40 50 60
MYPSTLPAEA DPSTMNGSSV AEPPDFQAAT AAAAAAARAS SLEQDEWSVG ECGFLDPDVQ
70 80 90 100 110 120
RTMRSGSAAE DITQYPMHGW VDVTKEFHDA CAELQPGELA QDMLFGLFEA MSAIEIMDPK
130 140 150 160 170 180
MDVGMGFDKQ DLPPPSFEAA IATGAIKLDD LTPSELIGIY DALFSCLVSW LEGNSMDQVL
190 200 210 220 230 240
FTCLYLHAPA QIKDKALRVF CTAVRNLIVV IKKIIAVAAV NEEEDFQLYG NSALLAAEKA
250 260 270 280 290 300
QPATVYSSLK DVEDELIRKC KKLTSTEDWM AVVHRLRFMR HLFQVIYHVE QMASNDTVDD
310 320 330 340 350 360
KVDIYKILLV ASEMLPGIRN TLDRGTQPEK GSDAPNPMGF SPRIHDRSQP PAFPRSIKIR
370 380 390 400 410 420
DRPSSYQFLE EMISRFKYAC KVTKYKDYYS ALNFFIEYSK KSGQCILSRS VLQTLFSANM
430 440 450 460 470 480
RMAHGKLPMK QFLRHSVQVF NSPPVLNAKH PVAADPKVQQ HLENFFRYCI NMNTFTQFIR
490 500 510 520 530 540
ICGFNRARQR DKLARLIENF DTIQVDAARL DSMMNQLANE RAMEGNEPMA TALKHSTHFS
550 560 570 580 590 600
TWVLYNCFRA MLIFLMSGFE LELYAVHEFL YIYWYPYEFL IGFLVSALTR TENILLAQEE
610 620 630 640 650 660
YAEHQSKTQS GGSGAAKNRK AAKPKKNKKT QRPYRAEIVF YHALLSLCGG MYKAMGALTK
670 680 690 700 710 720
DGRVRLPLSK FDNEEIRYNR RFLPFATLTS PPPVSYAEFK NVREHMMRHS VEDLYTYAAK
730 740 750 760 770 780
HFDQARNVLE SIQNPDQEML DLLQIARTNF VVMNVLARGH QKEVKRQPEF DFSKHSYFPI
IKLK