Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9VL59

Entry ID Method Resolution Chain Position Source
AF-Q9VL59-F1 Predicted AlphaFoldDB

No variants for Q9VL59

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9VL59

No associated diseases with Q9VL59

No regional properties for Q9VL59

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9VL59

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
DNA-binding transcription factor activity, RNA polymerase II-specific A DNA-binding transcription factor activity that modulates the transcription of specific gene sets transcribed by RNA polymerase II.
metal ion binding Binding to a metal ion.
RNA polymerase II cis-regulatory region sequence-specific DNA binding Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II.

2 GO annotations of biological process

Name Definition
negative regulation of DNA-templated transcription Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
regulation of transcription by RNA polymerase II Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8N5A5 ZGPAT Zinc finger CCCH-type with G patch domain-containing protein Homo sapiens (Human) PR
Q8VDM1 Zgpat Zinc finger CCCH-type with G patch domain-containing protein Mus musculus (Mouse) PR
10 20 30 40 50 60
MEEYEAQLLV VEQALENAAD DAQRQDLLAL KNNLQELLAL TRESGDEAPI DELPQQGDNL
70 80 90 100 110 120
DDELQRLKSE LNDLEAAGSS QTALDEERQL ADLRTKYTAM VGEKCSAPHE HSWGTCYHNA
130 140 150 160 170 180
LICGVDDEVV MNSEGVLDAR LRVLFTNPTH REMLPCSYYL EGECRFDEAK CRFSHGALVT
190 200 210 220 230 240
GSSIRKYNPP DFHKLSRSRP VFALLPDRLW HRGRVLCVNF VEQICRVRLD GQDHKERERD
250 260 270 280 290 300
FKFEELYPLT TDQDEDDELS SEESNSSMND NSSDEAESDM DDLEEARRAR MVELSLFTFK
310 320 330 340 350 360
PTERLGAWEE FTRGIGSKLM EKMGYIHGTG LGSDGRGIVT PVSAQILPQG RSLDACMELR
370 380 390 400 410 420
EAANGDKDYF SVERKLKRAQ RRQRKADEKA YVRESQRVDV FTFLNDSVLG PGESTQQGEQ
430 440 450 460 470 480
VTKKAKTNEL QQHSTKTLNV ETVRIADEIR RKQRDMAKVK QSLDRNSGDA QLQKRLQVQM
490 500 510
QSHKQELATL QAQERSLSKE QQTRKSKNKM FEF