Q9V411
Gene name |
Non1 |
Protein name |
Nucleolar GTP-binding protein 1 |
Names |
Novel nucleolar protein 1 |
Species |
Drosophila melanogaster (Fruit fly) |
KEGG Pathway |
dme:Dmel_CG8801 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9V411
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9V411-F1 | Predicted | AlphaFoldDB |
No variants for Q9V411
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9V411 | |||||
No associated diseases with Q9V411
8 regional properties for Q9V411
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Small GTP-binding protein domain | 169 - 317 | IPR005225 |
| domain | GTP binding domain | 171 - 191 | IPR006073-1 |
| domain | GTP binding domain | 192 - 210 | IPR006073-2 |
| domain | GTP binding domain | 219 - 234 | IPR006073-3 |
| domain | Nucleolar GTP-binding protein 1, Rossman-fold domain | 236 - 292 | IPR010674 |
| domain | NOG, C-terminal | 397 - 448 | IPR012973 |
| domain | OBG-type guanine nucleotide-binding (G) domain | 169 - 341 | IPR031167 |
| domain | NOG1, N-terminal helical domain | 6 - 165 | IPR041623 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleolus | A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| cell cycle | The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. |
| cell division | The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. |
| ribosomal large subunit biogenesis | A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis. |
3 homologous proteins in AiPD
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSLYNFKKIM | VVPPAKDFID | IMLSKTQRKT | PTVVHKGYKI | SRIRAFYTRK | VKYTQQNFHD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RLSQIIQDFP | KLDDVHPFYA | DLMNVLYDKD | HYKLALGQLN | TARHLVDNVA | KDYVRLLKYG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DSLYRCKQLK | KAALGRMATI | MKRQASNLTY | LEQVRQHLSR | LPTIDPYSRT | IIICGFPNVG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KSSFINKITR | ADVEVQPYAF | TTKSLYVGHT | DYKYLRWQVI | DTPGILDHPL | EERNVIEMQA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ITALAHLRAC | VLYFMDISEQ | CGHSLEEQVK | LFESIKPLFT | NKPLILAINK | IDILTPEDLP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EERRAIITKL | QEDKNIPVML | MSTVQETGVM | EVKTEACERL | LSYRVDQKMR | TKKVDNILNR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LHVAMPAPRD | DKLRAPCIPE | KASARLLQNA | DKAERKRKLE | KEIEEEMGDD | YTLDLKKNYS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| EIPEEERYDI | IPEFWQGHNI | ADYIDADIFD | KLEELEREEG | LREESGVYKV | PDMTMDETLK |
| 490 | 500 | 510 | 520 | 530 | 540 |
| EIREIAKQIR | GKRFELRDEK | RLSSRKNKPV | IPRNKQPKVR | DRSVQKLVST | MEGLGVDMSG |
| 550 | 560 | 570 | 580 | 590 | 600 |
| SENANFTKSV | VDLRRGQVAV | GSKKVPMQPL | LDKESSAVVR | KTGQPLKRAP | SRDTLGIKNL |
| 610 | 620 | 630 | 640 | 650 | |
| AIRKKAQIMA | KRDIAKKVTS | RGLKGEADRF | IGTKMPKHLF | SGKRGNGKTD | RR |