Q9TRY9
Gene name |
GLB1 |
Protein name |
Beta-galactosidase |
Names |
Acid beta-galactosidase, Lactase |
Species |
Canis lupus familiaris (Dog) (Canis familiaris) |
KEGG Pathway |
cfa:403873 |
EC number |
3.2.1.23: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9TRY9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9TRY9-F1 | Predicted | AlphaFoldDB |
3 variants for Q9TRY9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| 280 | Q>P | No | |||
| 442 | D>V | No | |||
| 444 | A>V | No |
No associated diseases with Q9TRY9
Functions
| Description | ||
|---|---|---|
| EC Number | 3.2.1.23 | Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular space | That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| lysosome | A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions. |
| vacuole | A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| beta-galactosidase activity | Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-D-galactosides. |
| protein homodimerization activity | Binding to an identical protein to form a homodimer. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular carbohydrate metabolic process | The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MARPAAVRVL | WALLLPLLLG | SARGLRNASQ | RTFTIDYSHN | RFLKDGQPFR | YISGSIHYSR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VPRFYWKDRL | LKMKMAGLNA | IQTYVPWNFH | EPQPGQYQFS | GEQDVEYFIK | LAHELGLLVI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LRPGPYICAE | WDMGGLPAWL | LLKESIILRS | SDPDYLAAVD | KWLGVLLPKM | KPLLYQNGGP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| IITMQVENEY | GSYFTCDYDY | LRFLQKLFHH | HLGNDVLLFT | TDGANEKFLQ | CGALQGLYAT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VDFGPGANIT | AAFQIQRKSE | PKGPLVNSEF | YTGWLDHWGQ | PHSTVRTEVV | ASSLHDILAH |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GANVNLYMFI | GGTNFAYWNG | ANMPYQAQPT | SYDYDAPLSE | AGDLTEKYFA | LREVIRKFEK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VPEGFIPPST | PKFAYGKVAL | KKLKTVEEAL | NVLCPPGPIN | SLYPLTFIQV | KQYFGFVMYR |
| 430 | 440 | 450 | 460 | 470 | 480 |
| TTLPQDCSDP | TPLSSPLSGV | HDRAYVSVDG | VPQGVMERSN | VITLNITGKA | GATLDLLVEN |
| 490 | 500 | 510 | 520 | 530 | 540 |
| MGRVNYGRYI | NDFKGLISNL | TLGSSILTNW | MIFPLNTEDA | VRSHLGGWHG | PNNGRHDKTF |
| 550 | 560 | 570 | 580 | 590 | 600 |
| AHRSSNYTLP | AFYMGNFSIP | SGIPDLPQDT | FIQFPGWTKG | QVWINGFNLG | RYWPARGPQM |
| 610 | 620 | 630 | 640 | 650 | 660 |
| TLFVPRHILV | TSTPNTIMVL | ELEHAPCGDS | GPEVCTVEFV | DRPVIGAPPT | PGHPPPDLSH |
| RDLRLDYV |