Q9SZZ8

PR
Gene name
BETA-OHASE (1, B1, CHY1, At4g25700, L73G19.80)
Protein name
Beta-carotene 3-hydroxylase 1, chloroplastic
Names
AtB1
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT4G25700
EC number
1.14.15.24: With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-125 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9SZZ8

Entry ID Method Resolution Chain Position Source
AF-Q9SZZ8-F1 Predicted AlphaFoldDB

16 variants for Q9SZZ8

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH00538164 5 L>V No 1000Genomes
ENSVATH08367056 28 R>C No 1000Genomes
tmp_4_13095686_C_G 61 E>Q No 1000Genomes
ENSVATH00538162 63 D>G No 1000Genomes
tmp_4_13095616_A_G 84 L>S No 1000Genomes
ENSVATH12225202 100 I>S No 1000Genomes
tmp_4_13095544_C_T 108 G>D No 1000Genomes
ENSVATH02923745 115 M>I No 1000Genomes
ENSVATH02923744 116 A>S No 1000Genomes
ENSVATH06774823 133 L>S No 1000Genomes
ENSVATH00538159 185 V>I No 1000Genomes
tmp_4_13094170_G_A 302 S>L No 1000Genomes
ENSVATH02923721 303 G>R No 1000Genomes
ENSVATH02923720 305 G>E No 1000Genomes
ENSVATH14295971 308 S>L No 1000Genomes
tmp_4_13094144_A_G 311 S>R No 1000Genomes

No associated diseases with Q9SZZ8

No regional properties for Q9SZZ8

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9SZZ8

Functions

Description
EC Number 1.14.15.24 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
Subcellular Localization
  • Plastid, chloroplast membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
chloroplast membrane Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

3 GO annotations of molecular function

Name Definition
hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
iron ion binding Binding to an iron (Fe) ion.
oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

1 GO annotations of biological process

Name Definition
xanthophyll biosynthetic process The chemical reactions and pathways resulting in the formation of xanthophylls, oxygen-containing carotenoids.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
O49814 CA2 Beta-carotene hydroxylase 2, chloroplastic Capsicum annuum (Capsicum pepper) PR
Q9LTG0 BETA-OHASE Beta-carotene 3-hydroxylase 2, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAAGLSTAVT FKPLHRSFSS SSTDFRLRLP KSLSGFSPSL RFKRFSVCYV VEERRQNSPI
70 80 90 100 110 120
ENDERPESTS STNAIDAEYL ALRLAEKLER KKSERSTYLI AAMLSSFGIT SMAVMAVYYR
130 140 150 160 170 180
FSWQMEGGEI SMLEMFGTFA LSVGAAVGME FWARWAHRAL WHASLWNMHE SHHKPREGPF
190 200 210 220 230 240
ELNDVFAIVN AGPAIGLLSY GFFNKGLVPG LCFGAGLGIT VFGIAYMFVH DGLVHKRFPV
250 260 270 280 290 300
GPIADVPYLR KVAAAHQLHH TDKFNGVPYG LFLGPKELEE VGGNEELDKE ISRRIKSYKK
ASGSGSSSSS