O49814

PR
Gene name
CA2
Protein name
Beta-carotene hydroxylase 2, chloroplastic
Names
Species
Capsicum annuum (Capsicum pepper)
KEGG Pathway
cann:107873401
EC number
1.14.15.24: With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-139 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O49814

Entry ID Method Resolution Chain Position Source
AF-O49814-F1 Predicted AlphaFoldDB

No variants for O49814

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O49814

No associated diseases with O49814

1 regional properties for O49814

Type Name Position InterPro Accession
domain Fatty acid hydroxylase 152 - 279 IPR006694

Functions

Description
EC Number 1.14.15.24 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
Subcellular Localization
  • Plastid, chloroplast membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
chloroplast membrane Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

4 GO annotations of molecular function

Name Definition
beta-carotene 3-hydroxylase activity Catalysis of the reaction: beta-carotene + a reduced electron acceptor + oxygen = beta-cryptoxanthin + an oxidized electron acceptor + H2O.
beta-cryptoxanthin hydroxylase activity Catalysis of the reaction: beta-cryptoxanthin + a reduced electron acceptor + oxygen = zeaxanthin + an oxidized electron acceptor + H2O.
hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
iron ion binding Binding to an iron (Fe) ion.

1 GO annotations of biological process

Name Definition
carotenoid biosynthetic process The chemical reactions and pathways resulting in the formation of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9LTG0 BETA-OHASE Beta-carotene 3-hydroxylase 2, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
Q9SZZ8 BETA-OHASE Beta-carotene 3-hydroxylase 1, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAAARISFSS TSRTSYYRHS PFLGPKPTPT TPSVYPITPF SPNLGSILRC RRRPSFTVCF
70 80 90 100 110 120
VLEDDKFKTQ FEAGEEDIEM KIEEQISATR LAEKLARKKS ERFTYLVAAV MSSFGITSMA
130 140 150 160 170 180
VMAVYYRFYW QMEGGEVPFS EMFGTFALSV GAAVGMEFWA RWAHKALWHA SLWHMHESHH
190 200 210 220 230 240
KPREGPFELN DVFAIINAVP AIALLDYGFF HKGLIPGLCF GAGLGITVFG MAYMFVHDGL
250 260 270 280 290 300
VHKRFPVGPV ANVPYLRKVA AAHSLHHSEK FNGVPYGLFL GPKELEEVGG LEELEKEVNR
RTRYIKGS