Q9SYM1
Gene name |
MSL6 (At1g78610, T30F21.6) |
Protein name |
Mechanosensitive ion channel protein 6 |
Names |
Mechanosensitive channel of small conductance-like 6, MscS-Like protein 6 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G78610 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9SYM1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9SYM1-F1 | Predicted | AlphaFoldDB |
29 variants for Q9SYM1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH05169457 | 9 | R>Q | No | 1000Genomes | |
| ENSVATH05169456 | 15 | I>T | No | 1000Genomes | |
| ENSVATH14492103 | 26 | S>F | No | 1000Genomes | |
| ENSVATH14492102 | 31 | G>E | No | 1000Genomes | |
| tmp_1_29571952_C_A | 59 | D>Y | No | 1000Genomes | |
| ENSVATH13835665 | 62 | R>K | No | 1000Genomes | |
| tmp_1_29571838_G_T | 97 | Q>K | No | 1000Genomes | |
| tmp_1_29571742_T_A | 129 | T>S | No | 1000Genomes | |
| tmp_1_29571696_T_C | 144 | N>S | No | 1000Genomes | |
| tmp_1_29571657_T_C | 157 | N>S | No | 1000Genomes | |
| ENSVATH01556062 | 162 | Q>L | No | 1000Genomes | |
| tmp_1_29571633_G_C | 165 | S>C | No | 1000Genomes | |
| ENSVATH13835663 | 189 | T>K | No | 1000Genomes | |
| ENSVATH05169453 | 206 | G>V | No | 1000Genomes | |
| ENSVATH14492099 | 255 | G>W | No | 1000Genomes | |
| tmp_1_29571256_C_G | 291 | V>L | No | 1000Genomes | |
| ENSVATH13835661 | 303 | I>V | No | 1000Genomes | |
| tmp_1_29570785_G_A | 448 | P>S | No | 1000Genomes | |
| tmp_1_29570778_T_G | 450 | K>T | No | 1000Genomes | |
| tmp_1_29570769_T_C | 453 | K>R | No | 1000Genomes | |
| ENSVATH01556050 | 459 | H>R | No | 1000Genomes | |
| ENSVATH05169451 | 477 | D>N | No | 1000Genomes | |
| ENSVATH01556049 | 496 | M>I | No | 1000Genomes | |
| ENSVATH13835657 | 638 | K>I | No | 1000Genomes | |
| tmp_1_29569645_A_T | 747 | L>H | No | 1000Genomes | |
| tmp_1_29569477_T_G | 774 | M>L | No | 1000Genomes | |
| tmp_1_29569364_T_G | 811 | K>N | No | 1000Genomes | |
| ENSVATH00148101 | 832 | L>M | No | 1000Genomes | |
| tmp_1_29569296_G_T | 834 | T>N | No | 1000Genomes |
No associated diseases with Q9SYM1
No regional properties for Q9SYM1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9SYM1 | |||
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plant-type vacuole | A closed structure that is completely surrounded by a unit membrane, contains liquid, and retains the same shape regardless of cell cycle phase. An example of this structure is found in Arabidopsis thaliana. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| plasmodesma | A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| mechanosensitive ion channel activity | Enables the transmembrane transfer of an ion by a channel that opens in response to a mechanical stress. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| anion transport | The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAVDAADRRE | VIVKIDGENG | NNNGVSGETV | GKIWRDGSYD | FWTDGEGNLN | KGHNAAAVDS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DRSAATTGEQ | QKDEGFEFRR | GEDPPTKLIG | QFLHKQQASG | EICLDMDLGM | DELQSRGLTP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VSESPRVSTK | RDPVGRRDSR | SNTNNNDDGE | VVKCSGNNAP | IQRSSSTLLK | MRTRSRLSDP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PTPQLPPQTA | DMKSGRIPKS | GQMKSGFFGK | SPKTQGEEEE | DDPFAAEDLP | EEYRKDKLSL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| WIVLEWLSLI | LIIAGFVCTL | AIPSLRKKKL | WELQLWKWES | MVLVLICGRL | VSSWIVKIVV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FFIERNFLLR | KRVLYFVYGV | RKAVQNCLWL | GLVLLAWHFL | FDEKVAKAAN | TKALRVVTKI |
| 370 | 380 | 390 | 400 | 410 | 420 |
| FVCLLVGFLL | WLVKTLLVKV | LASSFHMSTY | FDRIQESLFT | QYVIETLSGP | PLIEIQKNEE |
| 430 | 440 | 450 | 460 | 470 | 480 |
| EEERISVEVK | KFQNPGGVEI | QSGAQKSPMK | TGKSPFLSHV | LSNGGGGGGE | NKGITIDSLH |
| 490 | 500 | 510 | 520 | 530 | 540 |
| KLNPKNVSAW | KMKRLMNIIR | NGSLTTLDEQ | LQDPSLDDDK | GNQIRSEFEA | KLAARKIFHN |
| 550 | 560 | 570 | 580 | 590 | 600 |
| VAKPGSKFIY | ANDIMRFLPD | DEALKTLSLF | EGASETNRIS | KSSLKNWVVN | AFRERRALAL |
| 610 | 620 | 630 | 640 | 650 | 660 |
| TLNDTKTAVN | RLHKMVNIVV | GIIILVIWLI | ILGITSTKFL | VVMSSQVVVV | AFIFGNMCKI |
| 670 | 680 | 690 | 700 | 710 | 720 |
| VFESIIYLFV | IHPFDVGDRC | EIDGVQMVVE | EMNILTTVFL | RFDNQKVVYP | NSLLWTKSIG |
| 730 | 740 | 750 | 760 | 770 | 780 |
| NYYRSPDMGD | GIEFSIHITT | PAEKIILIKQ | RITSYIEGKK | DHWYPAPMIV | FKDMESLNSV |
| 790 | 800 | 810 | 820 | 830 | 840 |
| RIAVWPTHRM | NHQDMGEKWA | RRSQLVEEIA | KICRELDIEY | RLYPLDINVR | NLPTSTALPV |
| 850 | |||||
| SDRLPPNWSA | PASGSN |