Q9SIZ3
PR
Gene name |
At2g40280 (T07M07.16, T3G21.5, T7M7.24) |
Protein name |
Probable methyltransferase PMT23 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G40280 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9SIZ3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9SIZ3-F1 | Predicted | AlphaFoldDB |
46 variants for Q9SIZ3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH13593965 | 9 | V>F | No | 1000Genomes | |
| ENSVATH14601406 | 25 | F>L | No | 1000Genomes | |
| ENSVATH13593954 | 38 | S>Y | No | 1000Genomes | |
| ENSVATH13593953 | 40 | T>A | No | 1000Genomes | |
| tmp_2_16828177_A_T | 42 | Y>N | No | 1000Genomes | |
| ENSVATH00267248 | 46 | I>N | No | 1000Genomes | |
| tmp_2_16828144_G_A | 53 | H>Y | No | 1000Genomes | |
| tmp_2_16828138_T_C | 55 | I>V | No | 1000Genomes | |
| ENSVATH00267247 | 62 | Q>R | No | 1000Genomes | |
| tmp_2_16828024_G_A | 93 | P>S | No | 1000Genomes | |
| tmp_2_16827991_G_A | 104 | L>F | No | 1000Genomes | |
| tmp_2_16827895_C_G | 136 | V>L | No | 1000Genomes | |
| ENSVATH00267245 | 148 | D>V | No | 1000Genomes | |
| ENSVATH05690093 | 200 | K>Q | No | 1000Genomes | |
| ENSVATH13593945 | 203 | K>E | No | 1000Genomes | |
| tmp_2_16827355_G_A | 221 | S>F | No | 1000Genomes | |
| ENSVATH01972563 | 226 | D>G | No | 1000Genomes | |
| ENSVATH05690092 | 227 | V>A | No | 1000Genomes | |
| ENSVATH05690091 | 228 | I>L | No | 1000Genomes | |
| tmp_2_16827311_C_A | 236 | D>Y | No | 1000Genomes | |
| ENSVATH00267243 | 267 | N>K | No | 1000Genomes | |
| ENSVATH13593924 | 290 | L>F | No | 1000Genomes | |
| ENSVATH05690089 | 318 | R>K | No | 1000Genomes | |
| ENSVATH01972562 | 324 | V>I | No | 1000Genomes | |
| ENSVATH01972561 | 356 | S>C | No | 1000Genomes | |
| tmp_2_16826780_C_T | 357 | C>Y | No | 1000Genomes | |
| ENSVATH13593923 | 380 | V>I | No | 1000Genomes | |
| tmp_2_16826611_G_C | 383 | A>G | No | 1000Genomes | |
| tmp_2_16826518_G_A | 414 | S>L | No | 1000Genomes | |
| tmp_2_16826509_G_A | 417 | A>V | No | 1000Genomes | |
| tmp_2_16826486_C_T | 425 | E>K | No | 1000Genomes | |
| tmp_2_16826482_T_C | 426 | K>R | No | 1000Genomes | |
| tmp_2_16826462_C_T | 433 | D>N | No | 1000Genomes | |
| tmp_2_16826452_A_C | 436 | L>R | No | 1000Genomes | |
| ENSVATH05690083 | 449 | V>A | No | 1000Genomes | |
| ENSVATH13593922 | 454 | A>T | No | 1000Genomes | |
| tmp_2_16826283_C_T | 461 | A>T | No | 1000Genomes | |
| tmp_2_16826273_A_G | 464 | I>T | No | 1000Genomes | |
| tmp_2_16826222_G_C | 481 | T>S | No | 1000Genomes | |
| tmp_2_16825904_C_G | 525 | E>Q | No | 1000Genomes | |
| ENSVATH05690080 | 537 | V>A | No | 1000Genomes | |
| ENSVATH05690080 | 537 | V>E | No | 1000Genomes | |
| ENSVATH05690079 | 562 | L>I | No | 1000Genomes | |
| ENSVATH00267235 | 569 | Y>H | No | 1000Genomes | |
| ENSVATH05690078 | 572 | R>W | No | 1000Genomes | |
| ENSVATH01972547 | 589 | R>* | No | 1000Genomes |
No associated diseases with Q9SIZ3
7 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| endosome | A vacuole to which materials ingested by endocytosis are delivered. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| Golgi cis cisterna | The Golgi cisterna closest to the endoplasmic reticulum; the first processing compartment through which proteins pass after export from the ER. |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| trans-Golgi network | The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| methyltransferase activity | Catalysis of the transfer of a methyl group to an acceptor molecule. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| methylation | The process in which a methyl group is covalently attached to a molecule. |
5 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9C884 | At1g33170 | Probable methyltransferase PMT18 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZW75 | At2g43200 | Probable methyltransferase PMT19 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q84TJ0 | At3g10200 | Probable methyltransferase PMT6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SZX8 | At4g10440 | Probable methyltransferase PMT17 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LZA4 | At5g04060 | Probable methyltransferase PMT7 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAISVQHVVV | LLLSTLLIAI | TFFLFTSDNA | RFPFPSLSTT | DYYTPIPKSP | IPHRIVDVSS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DQTPQKMKLN | TSLEVGELKW | DLCKGAESVD | YIPCLDNYAA | IKQLKSRRHM | EHRERHCPEP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SPKCLLPLPD | NYKPPVPWPK | SRDMIWYDNV | PHPKLVEYKK | EQNWVKKEGE | FLVFPGGGTQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FKFGVTHYVE | FIEKALPSIK | WGKNIRVVLD | VGCGVASFGG | SLLDKDVITM | SFAPKDEHEA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QIQFALERGI | PATLSVIGTQ | QLTFPSNAFD | LIHCARCRVH | WDADGGKPLL | ELNRVLRPGG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FFIWSATPVY | RDNDRDSRIW | NEMVSLTKSI | CWKVVTKTVD | SSGIGLVIYQ | KPTSESCYNK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| RSTQDPPLCD | KKEANGSWYV | PLAKCLSKLP | SGNVQSWPEL | WPKRLVSVKP | QSISVKAETL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KKDTEKWSAS | VSDVYLKHLA | VNWSTVRNVM | DMNAGFGGFA | AALINLPLWV | MNVVPVDKPD |
| 490 | 500 | 510 | 520 | 530 | 540 |
| TLSVVYDRGL | IGVYHDWCES | VNTYPRTYDL | LHSSFLLGDL | TQRCEIVQVV | AEIDRIVRPG |
| 550 | 560 | 570 | 580 | ||
| GYLVVQDNME | TIMKLESILG | SLHWSTKIYE | DRFLVGRKGF | WRPAKPELR |