Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9LZA4

Entry ID Method Resolution Chain Position Source
AF-Q9LZA4-F1 Predicted AlphaFoldDB

45 variants for Q9LZA4

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_5_1099277_G_C 3 G>R No 1000Genomes
ENSVATH03019499 8 F>L No 1000Genomes
tmp_5_1099308_C_T 13 S>L No 1000Genomes
ENSVATH10555242 58 S>F No 1000Genomes
ENSVATH10555345 108 S>I No 1000Genomes
ENSVATH06919244 125 E>K No 1000Genomes
ENSVATH00605595 128 L>V No 1000Genomes
ENSVATH00605597 173 E>D No 1000Genomes
tmp_5_1100094_C_T 192 P>L No 1000Genomes
ENSVATH03019523 210 L>R No 1000Genomes
tmp_5_1100279_G_A 213 G>R No 1000Genomes
tmp_5_1100384_G_C 248 E>Q No 1000Genomes
ENSVATH00605601 260 R>G No 1000Genomes
ENSVATH10555351 281 V>I No 1000Genomes
ENSVATH03019526 289 D>E No 1000Genomes
tmp_5_1100513_C_T 291 H>Y No 1000Genomes
ENSVATH06919252 296 V>I No 1000Genomes
ENSVATH03019529 298 M>I No 1000Genomes
ENSVATH10555352 318 A>T No 1000Genomes
ENSVATH10555353 354 V>I No 1000Genomes
ENSVATH00605606 358 D>A No 1000Genomes
ENSVATH00605607 375 G>D No 1000Genomes
ENSVATH03019530 375 G>S No 1000Genomes
ENSVATH06919254 379 V>L No 1000Genomes
tmp_5_1100875_T_C 380 S>P No 1000Genomes
ENSVATH10555354 380 S>W No 1000Genomes
tmp_5_1100933_A_T 399 Q>L No 1000Genomes
ENSVATH03019532 406 T>I No 1000Genomes
ENSVATH03019533 407 D>E No 1000Genomes
tmp_5_1100994_A_T 419 K>N No 1000Genomes
ENSVATH06919257 423 E>K No 1000Genomes
tmp_5_1101098_C_T 430 T>I No 1000Genomes
ENSVATH10555438 461 I>F No 1000Genomes
tmp_5_1101247_C_A 480 P>T No 1000Genomes
tmp_5_1101309_T_A 500 H>Q No 1000Genomes
tmp_5_1101438_T_A 516 L>Q No 1000Genomes
ENSVATH00605611 528 Y>H No 1000Genomes
tmp_5_1101495_A_G 535 E>G No 1000Genomes
tmp_5_1101664_A_T 553 I>F No 1000Genomes
ENSVATH00605615 562 R>S No 1000Genomes
tmp_5_1101713_A_T 569 K>M No 1000Genomes
ENSVATH00605617 576 A>T No 1000Genomes
ENSVATH06919264 592 C>G No 1000Genomes
ENSVATH10555441 599 I>N No 1000Genomes
ENSVATH03019540 600 L>V No 1000Genomes

No associated diseases with Q9LZA4

1 regional properties for Q9LZA4

Type Name Position InterPro Accession
domain BTB/POZ domain 99 - 172 IPR000210

Functions

Description
EC Number
Subcellular Localization
  • Golgi apparatus membrane ; Single-pass type II membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

6 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
endosome A vacuole to which materials ingested by endocytosis are delivered.
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
trans-Golgi network The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.

1 GO annotations of molecular function

Name Definition
methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule.

1 GO annotations of biological process

Name Definition
methylation The process in which a methyl group is covalently attached to a molecule.

5 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q84TJ0 At3g10200 Probable methyltransferase PMT6 Arabidopsis thaliana (Mouse-ear cress) PR
Q9C884 At1g33170 Probable methyltransferase PMT18 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SIZ3 At2g40280 Probable methyltransferase PMT23 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZW75 At2g43200 Probable methyltransferase PMT19 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SZX8 At4g10440 Probable methyltransferase PMT17 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MGGGYVLFGS ARSGQMIMVA LVLMVGSFYA GSIFGNNSPI YISQPSSSNS SSSSPSQSGP
70 80 90 100 110 120
SNFANKIELT YRRTSVSIPE SGVNVCPLKF NEYIPCHNVT YVQQLLPSLN LSRREELERH
130 140 150 160 170 180
CPPLEQRLFC LVPPPKDYKI PIRWPTSRDY VWRSNVNHTH LAEVKGGQNW VHEQGQLWWF
190 200 210 220 230 240
PGGGTHFKHG APEYIQRLGN MTTNETGDLL SAGVEQVLDV GCGVASFAAY LLPLGIKTMS
250 260 270 280 290 300
FAPKDGHENQ IQFALERGIR AMISAIATKQ MPYPAASFDM VHCSRCRVDW HENDGVLMKE
310 320 330 340 350 360
VNRLLRPNGY FVYSAPPAYR KDKDFPVIWD KLVNLTSAMC WKLISRKVQT AIWVKEDDEA
370 380 390 400 410 420
CLRKNAELEL ITICGVEDVS KASWKVPLRD CVDISENRQQ KPSSLTDRLS SYPTSLREKG
430 440 450 460 470 480
ISEDEFTLDT NFWREQVNQY WELMNVNKTE VRNVMDTNAF IGGFAAAMNS YPLWVMNVVP
490 500 510 520 530 540
ATMNDTLSGI YQRGLTGAYH DWCEPFSTYP RTYDLLHADH LFTHYKIYGE GCLLEDIMLE
550 560 570 580 590
MDRIIRPQGF IIIRDEESIV SRVRDLAPKF LWEVEAHELQ DKYKKTETVL FCRKKFWAIL