Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9SD81

Entry ID Method Resolution Chain Position Source
AF-Q9SD81-F1 Predicted AlphaFoldDB

32 variants for Q9SD81

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH00611705 18 N>D No 1000Genomes
ENSVATH00611704 18 N>K No 1000Genomes
tmp_5_2576627_G_T 23 P>T No 1000Genomes
ENSVATH06939532 40 Q>H No 1000Genomes
ENSVATH03036635 58 E>* No 1000Genomes
tmp_5_2576507_C_T 63 A>T No 1000Genomes
ENSVATH00611699 74 F>L No 1000Genomes
tmp_5_2576343_C_T 93 V>I No 1000Genomes
ENSVATH06939529 111 K>* No 1000Genomes
ENSVATH06939523 130 T>I No 1000Genomes
tmp_5_2576144_T_G 130 T>P No 1000Genomes
ENSVATH10646150 133 E>K No 1000Genomes
ENSVATH00611698 141 Q>* No 1000Genomes
ENSVATH00611697 142 R>M No 1000Genomes
ENSVATH06939522 149 Q>K No 1000Genomes
tmp_5_2576069_G_A 155 P>S No 1000Genomes
ENSVATH06939521 156 I>N No 1000Genomes
ENSVATH10646149 160 D>E No 1000Genomes
ENSVATH06939520 168 D>E No 1000Genomes
ENSVATH00611696 174 G>A No 1000Genomes
ENSVATH10646121 189 V>L No 1000Genomes
ENSVATH06939517 199 D>E No 1000Genomes
ENSVATH06939515 203 E>G No 1000Genomes
ENSVATH10646119 209 G>E No 1000Genomes
tmp_5_2575746_G_T 232 T>N No 1000Genomes
ENSVATH03036632 235 V>I No 1000Genomes
tmp_5_2575732_T_C 237 I>V No 1000Genomes
tmp_5_2575716_T_A 242 D>V No 1000Genomes
tmp_5_2575535_G_T 277 P>Q No 1000Genomes
ENSVATH10646074 320 R>H No 1000Genomes
tmp_5_2575292_G_T 327 H>N No 1000Genomes
ENSVATH06939509 372 Q>K No 1000Genomes

No associated diseases with Q9SD81

1 regional properties for Q9SD81

Type Name Position InterPro Accession
domain Glycerophosphodiester phosphodiesterase domain 44 - 362 IPR030395

Functions

Description
EC Number 3.1.4.46 Phosphoric diester hydrolases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
glycerophosphodiester phosphodiesterase activity Catalysis of the reaction: a glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate.

2 GO annotations of biological process

Name Definition
glycerol metabolic process The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
lipid metabolic process The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P09394 glpQ Glycerophosphodiester phosphodiesterase, periplasmic Escherichia coli (strain K12) PR
Q6W3E5 GDPD4 Glycerophosphodiester phosphodiesterase domain-containing protein 4 Homo sapiens (Human) PR
10 20 30 40 50 60
MAFKYLLPLL LLSLLVANCA SRPLYRLPSE AKHATKKPLQ TSRPYNLAHR GSNGELPEET
70 80 90 100 110 120
APAYMRAIEE GADFIETDIL SSKDGVLICH HDVNLDDTTD VADHKEFADR KRTYEVQGMN
130 140 150 160 170 180
MTGFFTVDFT LKELKTLGAK QRYPFRDQQY NGKFPIITFD EYISIALDAP RVVGIYPEIK
190 200 210 220 230 240
NPVFMNQQVK WADGKKFEDK FVETLKKYGY KGSYLSEDWL KQPIFIQSFA ATSLVYISNM
250 260 270 280 290 300
TDSPKLFLID DVTILTEDTN KTYAEITSDA YLDYIKPYVI GIGPWKDTIV PVNNNRLMTP
310 320 330 340 350 360
TDLVARAHSR NLQVHPYTYR NENQFLHLEF NQDPYLEYDY WLNKIGVDGL FTDFTGSLHN
370
YQELKSPLPQ QQ