P09394
Gene name |
glpQ (b2239, JW2233) |
Protein name |
Glycerophosphodiester phosphodiesterase, periplasmic |
Names |
Glycerophosphoryl diester phosphodiesterase, periplasmic |
Species |
Escherichia coli (strain K12) |
KEGG Pathway |
eco:b2239 |
EC number |
3.1.4.46: Phosphoric diester hydrolases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
3 structures for P09394
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 1T8Q | X-ray | 200 A | A/B/C/D | 25-358 | PDB |
| 1YDY | X-ray | 170 A | A/B | 1-356 | PDB |
| AF-P09394-F1 | Predicted | AlphaFoldDB |
No variants for P09394
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P09394 | |||||
No associated diseases with P09394
1 regional properties for P09394
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Glycerophosphodiester phosphodiesterase domain | 31 - 355 | IPR030395 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.4.46 | Phosphoric diester hydrolases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| periplasmic space | The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria). |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| calcium ion binding | Binding to a calcium ion (Ca2+). |
| glycerophosphodiester phosphodiesterase activity | Catalysis of the reaction: a glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate. |
| metal ion binding | Binding to a metal ion. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| glycerol metabolic process | The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids. |
| lipid metabolic process | The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9SD81 | GDPD6 | Glycerophosphodiester phosphodiesterase GDPD6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKLTLKNLSM | AIMMSTIVMG | SSAMAADSNE | KIVIAHRGAS | GYLPEHTLPA | KAMAYAQGAD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YLEQDLVMTK | DDNLVVLHDH | YLDRVTDVAD | RFPDRARKDG | RYYAIDFTLD | EIKSLKFTEG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FDIENGKKVQ | TYPGRFPMGK | SDFRVHTFEE | EIEFVQGLNH | STGKNIGIYP | EIKAPWFHHQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EGKDIAAKTL | EVLKKYGYTG | KDDKVYLQCF | DADELKRIKN | ELEPKMGMEL | NLVQLIAYTD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| WNETQQKQPD | GSWVNYNYDW | MFKPGAMKQV | AEYADGIGPD | YHMLIEETSQ | PGNIKLTGMV |
| 310 | 320 | 330 | 340 | 350 | |
| QDAQQNKLVV | HPYTVRSDKL | PEYTPDVNQL | YDALYNKAGV | NGLFTDFPDK | AVKFLNKE |