Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9QZM9

Entry ID Method Resolution Chain Position Source
AF-Q9QZM9-F1 Predicted AlphaFoldDB

12 variants for Q9QZM9

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3389353482 30 L>M No EVA
rs3405295093 118 Y>* No EVA
rs3389353460 138 W>R No EVA
rs3405109476 160 V>G No EVA
rs3389320201 202 S>T No EVA
rs3389292192 203 S>P No EVA
rs3389336217 212 G>R No EVA
rs3389348861 226 P>S No EVA
rs212748725 250 R>G No EVA
rs3389301516 254 T>I No EVA
rs3389320184 285 S>F No EVA
rs3389301462 291 V>L No EVA

No associated diseases with Q9QZM9

1 regional properties for Q9QZM9

Type Name Position InterPro Accession
domain F-box domain 86 - 133 IPR001810

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

5 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q969H0 FBXW7 F-box/WD repeat-containing protein 7 Homo sapiens (Human) PR
Q8N3Y1 FBXW8 F-box/WD repeat-containing protein 8 Homo sapiens (Human) PR
Q008S8 ECT2L Epithelial cell-transforming sequence 2 oncogene-like Homo sapiens (Human) PR
Q8BIA4 Fbxw8 F-box/WD repeat-containing protein 8 Mus musculus (Mouse) PR
P0DL28 Fbxw8 F-box/WD repeat-containing protein 8 Rattus norvegicus (Rat) PR
10 20 30 40 50 60
MMAFAPPKSI DGPKMQTKMS TWTPLNHQLL NDQVFEERRA LLGKWFDKWT DSQRRRILTG
70 80 90 100 110 120
LLERCSLSQQ KFCCRKLQEK IPAEALDFTT KLPRVLSVYI FSFLDPRSLC RCAQVSWYWK
130 140 150 160 170 180
SLAELDQLWM LKCLRFNWYI SFSPTPFEQG VWKKHYIQMV RELHVTKPKT PPKDEFTTAD
190 200 210 220 230 240
VQPIPGNSPD EKQSPSLAFR SSSSLRKKNN PGEKELPPWR SSDKHPTDII RFNYLDNCDP
250 260 270 280 290 300
ELFRLGRRKR SEVTPDFKRQ LRDKKNKLQD RARLRKAQSL ISLSSPPKVP VRLAWPLHLP
310 320 330
VAPSDREAAT EALLEHLQKH PGLQSPSPRL QSQS