Q9QYE6
Gene name |
Golga5 (Retii) |
Protein name |
Golgin subfamily A member 5 |
Names |
Golgin-84, Protein Ret-II, Protein Sumiko |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:27277 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9QYE6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9QYE6-F1 | Predicted | AlphaFoldDB |
31 variants for Q9QYE6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3389258562 | 27 | R>G | No | EVA | |
| rs29149218 | 57 | G>E | No | EVA | |
| rs3403658730 | 69 | N>K | No | EVA | |
| rs245232242 | 92 | G>R | No | EVA | |
| rs13471560 | 93 | D>N | No | EVA | |
| rs225716477 | 103 | A>V | No | EVA | |
| rs3389264755 | 120 | D>Y | No | EVA | |
| rs242678337 | 140 | V>I | No | EVA | |
| rs3389258584 | 143 | E>D | No | EVA | |
| rs29142801 | 145 | G>D | No | EVA | |
| rs585660551 | 150 | S>F | No | EVA | |
| rs37322375 | 159 | S>P | No | EVA | |
| rs3403829875 | 163 | S>R | No | EVA | |
| rs244409683 | 171 | G>E | No | EVA | |
| rs262415510 | 172 | G>E | No | EVA | |
| rs231232372 | 173 | N>K | No | EVA | |
| rs252321893 | 174 | A>S | No | EVA | |
| rs253962937 | 193 | E>K | No | EVA | |
| rs243557484 | 206 | E>V | No | EVA | |
| rs3402287733 | 228 | E>D | No | EVA | |
| rs3389271386 | 253 | T>I | No | EVA | |
| rs3389256900 | 392 | T>S | No | EVA | |
| rs3389252000 | 404 | K>N | No | EVA | |
| rs29175683 | 417 | A>S | No | EVA | |
| rs3389257294 | 437 | L>F | No | EVA | |
| rs3389224121 | 469 | L>F | No | EVA | |
| rs3389254377 | 530 | E>D | No | EVA | |
| rs47514198 | 640 | S>P | No | EVA | |
| rs3389251997 | 649 | R>C | No | EVA | |
| rs3389241969 | 672 | R>L | No | EVA | |
| rs3389258600 | 678 | I>M | No | EVA |
No associated diseases with Q9QYE6
No regional properties for Q9QYE6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9QYE6 | |||
9 GO annotations of cellular component
| Name | Definition |
|---|---|
| cis-Golgi network | The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum. |
| COPI-coated vesicle membrane | The lipid bilayer surrounding a COPI-coated vesicle. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| Golgi cis cisterna | The Golgi cisterna closest to the endoplasmic reticulum; the first processing compartment through which proteins pass after export from the ER. |
| Golgi cisterna | Any of the thin, flattened membrane-bounded compartments that form the central portion of the Golgi complex. |
| Golgi medial cisterna | The middle Golgi cisterna (or cisternae). |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| Golgi trans cisterna | The Golgi cisterna farthest from the endoplasmic reticulum; the final processing compartment through which proteins pass before exiting the Golgi apparatus; the compartment in which N-linked protein glycosylation is completed. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein homodimerization activity | Binding to an identical protein to form a homodimer. |
| protein-macromolecule adaptor activity | The binding activity of a protein that brings together two or more macromolecules in contact, permitting those molecules to function in a coordinated way. The adaptor can bring together two proteins, or a protein and another macromolecule such as a lipid or a nucleic acid. |
| small GTPase binding | Binding to a small monomeric GTPase. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| Golgi organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus. |
| Golgi vesicle transport | The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles. |
| retrograde transport, vesicle recycling within Golgi | The retrograde movement of substances within the Golgi, mediated by COP I vesicles. Cis-Golgi vesicles are constantly moving forward through the Golgi stack by cisternal progression, eventually becoming trans-Golgi vesicles. They then selectively transport membrane and luminal proteins from the trans- to the medial-Golgi while leaving others behind in the trans-Golgi cisternae; similarly, they selectively move proteins from the medial- to the cis-Golgi. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSWFADLAGR | AEDLLNRVDQ | GAATALRKEN | TSNIFYSKNT | DYPELQQQNT | DSNYQTGQKA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NYISSAADNI | RHQKATILAG | TANVKVGSRT | VGDATHPTEH | ASAPRPSSQF | VRRKKSEPDD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ELLFDFLNSS | QKEPTGRVEV | KKEKGRAPVS | PSSPSGVSSV | NTSVTTTKAM | GGNAGSQSPG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VNSSDSVPEV | HKEPSEESTA | PSATSEEHSS | TPSDGSSRSQ | ELSNLRLENQ | LLRNEVQSLN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QEMASLLQRS | KETQEELNKA | RVRVEKWNVD | NSKSDRITRE | LRAQVDDLTE | AVAAKDSQLA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VLKVRLQEAD | QVLSSRTEAL | EALRSEKSRI | MQDHKEGSSL | QNQALQTLQE | RLHEADATLK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| REQESYKQMQ | SEFAARLNKM | EVDRQNLAEA | VTLAERKYSE | EKKKVDELQQ | QVKLHRASLE |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SAKQELVDYK | QKATRILQSK | EKLINSLKEG | SSFEGLESST | ASSMELEELR | HEKEMQKEEI |
| 490 | 500 | 510 | 520 | 530 | 540 |
| QKLMGQMHQL | RSELQDMEAQ | QVSEAESARE | QLQDLQDQIA | KQRTSKQELE | TELERMKQEF |
| 550 | 560 | 570 | 580 | 590 | 600 |
| RYMEEDLHRT | KNTLQSRIKD | REEEIQKLRN | QLTNKTLSNS | SQSELESRLH | QLTETLIQKQ |
| 610 | 620 | 630 | 640 | 650 | 660 |
| TMLESLSTEK | NSLVFQLERL | EQQVHSASSG | PNSGSAINMS | GVDSGEGTRL | RNVPVLFNDT |
| 670 | 680 | 690 | 700 | 710 | 720 |
| ETNLAGMYGK | VRKAASSIDQ | FSIRLGIFLR | RYPIARVFVI | IYMALLHLWV | MIVLLTYSPE |
| MHHDQPYGK |