Q8SZ63
Gene name |
Golgin84 (CG17785) |
Protein name |
Golgin-84 |
Names |
|
Species |
Drosophila melanogaster (Fruit fly) |
KEGG Pathway |
dme:Dmel_CG17785 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8SZ63
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8SZ63-F1 | Predicted | AlphaFoldDB |
No variants for Q8SZ63
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8SZ63 | |||||
No associated diseases with Q8SZ63
No regional properties for Q8SZ63
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q8SZ63 | |||
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| Golgi cisterna | Any of the thin, flattened membrane-bounded compartments that form the central portion of the Golgi complex. |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein homodimerization activity | Binding to an identical protein to form a homodimer. |
| small GTPase binding | Binding to a small monomeric GTPase. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| Golgi organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus. |
| Golgi vesicle transport | The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles. |
| retrograde transport, vesicle recycling within Golgi | The retrograde movement of substances within the Golgi, mediated by COP I vesicles. Cis-Golgi vesicles are constantly moving forward through the Golgi stack by cisternal progression, eventually becoming trans-Golgi vesicles. They then selectively transport membrane and luminal proteins from the trans- to the medial-Golgi while leaving others behind in the trans-Golgi cisternae; similarly, they selectively move proteins from the medial- to the cis-Golgi. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSSWITGLAD | KAENILNKLD | QNAATALQTE | NATGSADPMR | RSMTSSTQSL | STSLKSTLSP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VRRSGANSSS | SVKSDGGVSV | VTKDMRQKMT | TSASFSNSPD | ISANSMDTNE | LAAFKIALNE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ITAERDELRL | RLEDLNNETE | KFDLHQHTQV | LEALVKSLSE | ERDKAVHDYN | EAQAANMAYV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| HSISELETNL | AKLQQEYISA | AHKLQMQTKE | TEQQRQELQE | YRIKAQRALQ | AKDSLIAELK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AKPTEEGADP | NLVSKDSETR | FLQIEHESLK | QELEHANEEL | QKARLQLDDY | VSQERQRQVE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LSSARQREET | LAKELRQARE | HSVTSESDQR | VLTQELASLR | QQLSNQMAAA | ATRLQEREQQ |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LQQMRQRLSE | EANTGAKSDY | ETRLKALTQS | LVERQSLLER | VTSERNALRL | QHEKAQTQLQ |
| 430 | 440 | 450 | 460 | 470 | 480 |
| QNMHLVEMES | QRGSSRHTML | NSTDDVKAQF | PLLMHPSPFD | NRVARRFKRA | LRQADSMGIR |
| 490 | 500 | 510 | |||
| VGTFLRRYPM | MRVSVIVYVA | LLHLWVMFVL | LSTTPN |