Q9QY83
Gene name |
Actl7b (Tact1) |
Protein name |
Actin-like protein 7B |
Names |
Actin-like-7-beta, Testis-specific actin-1, T-actin-1 |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:11471 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9QY83
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9QY83-F1 | Predicted | AlphaFoldDB |
10 variants for Q9QY83
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3388686271 | 36 | T>I | No | EVA | |
| rs3388673264 | 57 | D>Y | No | EVA | |
| rs3388687911 | 193 | G>D | No | EVA | |
| rs3388689632 | 244 | G>C | No | EVA | |
| rs3388687962 | 366 | C>Y | No | EVA | |
| rs3388680413 | 368 | G>R | No | EVA | |
| rs3388686909 | 410 | G>D | No | EVA | |
| rs3388673334 | 411 | C>Y | No | EVA | |
| rs3388686849 | 412 | A>V | No | EVA | |
| rs3388672706 | 413 | A>V | No | EVA |
No associated diseases with Q9QY83
No regional properties for Q9QY83
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9QY83 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| dynactin complex | A 20S multiprotein assembly of total mass about 1.2 MDa that activates dynein-based activity in vivo. A large structural component of the complex is an actin-like 40 nm filament composed of actin-related protein, to which other components attach. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
6 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q32KZ2 | ACTL7A | Actin-like protein 7A | Bos taurus (Bovine) | PR |
| Q9Y615 | ACTL7A | Actin-like protein 7A | Homo sapiens (Human) | PR |
| Q9H568 | ACTL8 | Actin-like protein 8 | Homo sapiens (Human) | PR |
| Q9Y614 | ACTL7B | Actin-like protein 7B | Homo sapiens (Human) | PR |
| Q80US4 | Actr5 | Actin-related protein 5 | Mus musculus (Mouse) | PR |
| Q4QR76 | Actl7b | Actin-like protein 7B | Rattus norvegicus (Rat) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MATKNSPSPK | PMGTAQGDPG | EAGTLPAPEA | AGIRDTGSTQ | LKTKPKKIRK | IKALVIDLGS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QYCKCGYAGE | PRPTYFISST | VGKRSAEMAA | DAGDNFKETY | VGHELLNMEA | SLKLVNPLKH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GVVVDWDCIQ | NIWEYIFHTA | MKIMPEEHAV | LVSDPPLSPT | SNREKYAELL | FETFGIPAMH |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VTSQALLSIY | SYGKTSGLVV | ESGHGVSHVV | PISEGDLLPG | LPSRVDYAGC | DLTNYLMQLL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NEAGHKFSDD | HLHIIEHIKK | KCCYAALLPE | EEMSLGLDEL | HVDYELPDGK | IITIGQERFR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| CSEMLFKPSL | VGCTQPGLPE | LTATCLARCQ | GTGFKEEMAA | NVLLCGGCTM | LDGFPERFQR |
| 370 | 380 | 390 | 400 | 410 | |
| ELSLLCPGDS | PTVAAAPERK | TSVWTGGSIL | ASLQAFQQLW | VSKEEFEERG | CAAIYSKC |