Q80US4

PR
Gene name
Actr5
Protein name
Actin-related protein 5
Names
Species
Mus musculus (Mouse)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-52 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q80US4

Entry ID Method Resolution Chain Position Source
AF-Q80US4-F1 Predicted AlphaFoldDB

No variants for Q80US4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q80US4

No associated diseases with Q80US4

1 regional properties for Q80US4

Type Name Position InterPro Accession
conserved_site Actin, conserved site 552 - 560 IPR004001

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
Ino80 complex A multisubunit protein complex that contains the Ino80p ATPase; exhibits chromatin remodeling activity.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

15 GO annotations of biological process

Name Definition
chromatin remodeling A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication.
DNA recombination Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
double-strand break repair The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.
positive regulation of DNA repair Any process that activates or increases the frequency, rate or extent of DNA repair.
positive regulation of DNA-templated transcription Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
positive regulation of telomere maintenance in response to DNA damage Any process that activates or increases the frequency, rate or extent of telomere maintenance in response to DNA damage.
regulation of cell cycle Any process that modulates the rate or extent of progression through the cell cycle.
regulation of chromosome organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome.
regulation of DNA repair Any process that modulates the frequency, rate or extent of DNA repair.
regulation of DNA replication Any process that modulates the frequency, rate or extent of DNA replication.
regulation of DNA strand elongation Any process that modulates the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which an existing DNA strand is extended by activities including the addition of nucleotides to the 3' end of the strand.
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
regulation of embryonic development Any process that modulates the frequency, rate or extent of embryonic development.
telomere maintenance Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.
UV-damage excision repair A DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site. UV-damage excision repair acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs).

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9QY83 Actl7b Actin-like protein 7B Mus musculus (Mouse) PR
A2ZP58 ARP5 Actin-related protein 5 Oryza sativa subsp japonica (Rice) PR
10 20 30 40 50 60
MEANVFRFRD ARSAPDPVLE AGPVAFGSQP VPLVLDNGSF QARAGWACPG PDPGPEPRLQ
70 80 90 100 110 120
FRAVCARGRG GARGGPGPQV GNALGSLEPL RWMLRSPFDR NVPVNLELQE LLLDYSFQHL
130 140 150 160 170 180
GVSSQGCVDH PIVLTEAVCN PLYSRQMMSE LLFECYRIPK VAYGIDSLFS FYHNVPKNAL
190 200 210 220 230 240
SSGLIISSGY QCTHILPVLE GRLDAKNCKR INLGGSQAAG YLQRLLQLKY PGHLAAITLS
250 260 270 280 290 300
RMEEILQEHS YIAEDYGAEL QKWQCPDYYE NNVHKMQLPF SSKLLGSTLT AEEKQERRQQ
310 320 330 340 350 360
QLRRLQELNA RRREEKLQLD QERLERLLYV QELLEEGQMD QFHKALIELN MDSPEELQSY
370 380 390 400 410 420
IQKLTLAVEQ AKQKILQAEA SLEVDVVDSK PETPDLEPLE PTMEDVENIS DFEPLFSEET
430 440 450 460 470 480
PEVEKPQVTT VQPVFNLAAY HQLSVGTERI RAPEIIFQPS LIGEEQAGIA ETLHFVLDRY
490 500 510 520 530 540
PKAIQDTLVQ NVFLTGGNVM YPGMKARVEK ELLEMRPFQS SFQVQLASNP VLDAWYGARD
550 560 570 580 590 600
WALDHLEDSG AWVTRKDYEE KGGEYLKEHC ASNTYVPIRL PKQASRASET QTSGRGSSAS
GSGAG