Q9MYU8

PR
Gene name
EPB41L5 (BE37)
Protein name
Band 4.1-like protein 5
Names
NTPDase 1, Ecto-ATP diphosphohydrolase 1, Ecto-ATPDase 1, Ecto-ATPase 1, Ecto-apyrase, Lymphoid cell activation antigen, Erythrocyte membrane protein band 4.1-like 5
Species
Canis lupus familiaris (Dog) (Canis familiaris)
KEGG Pathway
cfa:403419
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-60 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9MYU8

Entry ID Method Resolution Chain Position Source
AF-Q9MYU8-F1 Predicted AlphaFoldDB

No variants for Q9MYU8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9MYU8

No associated diseases with Q9MYU8

8 regional properties for Q9MYU8

Type Name Position InterPro Accession
domain FERM domain 43 - 327 IPR000299
domain FERM adjacent 336 - 380 IPR014847
domain FERM, N-terminal 47 - 109 IPR018979
domain FERM, C-terminal PH-like domain 239 - 331 IPR018980
conserved_site FERM conserved site 97 - 126 IPR019747-1
conserved_site FERM conserved site 205 - 234 IPR019747-2
domain FERM central domain 127 - 235 IPR019748
domain Band 4.1 domain 39 - 235 IPR019749

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Cell junction, adherens junction
  • Cell membrane ; Peripheral membrane protein
  • Photoreceptor inner segment
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
adherens junction A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytoskeleton A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
photoreceptor inner segment The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
cytoskeletal protein binding Binding to a protein component of a cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).

1 GO annotations of biological process

Name Definition
actomyosin structure organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments.

3 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q58CU2 EPB41L5 Band 4.1-like protein 5 Bos taurus (Bovine) PR
Q9HCM4 EPB41L5 Band 4.1-like protein 5 Homo sapiens (Human) PR
Q8BGS1 Epb41l5 Band 4.1-like protein 5 Mus musculus (Mouse) PR
10 20 30 40 50 60
MLSFFRRTLG RRSMRKHAEK ERLREAQRAA THIPAAGDSK SIITCRVSLL DGTDVSVDLP
70 80 90 100 110 120
KKAKGQELFD QIMYHLDLIE SDYFGLRFMD SAQVAHWLDG TKSIKKQVKI GSPYCLHLRV
130 140 150 160 170 180
KFYSSEPNNL REELTRYLFV LQLKQDILSG KLECPFDTAV QLAAYNLQAE LGDYDLAEHS
190 200 210 220 230 240
PELVSEFRFV PIQTEEMELA IFEKWKEYRG QTPAQAETNY LNKAKWLEMY GVDMHVVKAR
250 260 270 280 290 300
DGNDYSLGLT PTGVLVFEGE TKIGLFFWPK ITRLDFKKNK LTLVVVEDDV QGKEQEHTFV
310 320 330 340 350 360
FRLDHPKACK HLWKCAVEHH AFFRLRGPVQ KSSHRSGFIR LGSRFRYSGK TEYQTTKTNK
370 380 390 400 410 420
ARRSTSFERR PSKRYSRRTL QMKASTAKPE ELSVHNNVST QSNGSQQAWS VRSTLPVIPS
430 440 450 460 470 480
VPSGPVLAEI ENLPRNPGSN QYDRKWVSAA SDCCQRGGNQ WNTRALSPPQ PAHRNYTDFV
490 500
HEHNVKNTGV HHDVHFPGHA AMTEI