Q9MAR8
Gene name |
SCPL44 (At1g43780, F28H19.3, F28H19.5) |
Protein name |
Serine carboxypeptidase-like 44 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G43780 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9MAR8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9MAR8-F1 | Predicted | AlphaFoldDB |
44 variants for Q9MAR8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_1_16563814_G_C | 2 | V>L | No | 1000Genomes | |
| tmp_1_16563830_G_A | 7 | R>Q | No | 1000Genomes | |
| tmp_1_16563841_G_T | 11 | V>L | No | 1000Genomes | |
| tmp_1_16563847_G_A | 13 | V>I | No | 1000Genomes | |
| tmp_1_16563853_G_T | 15 | V>L | No | 1000Genomes | |
| ENSVATH13330510 | 16 | M>I | No | 1000Genomes | |
| tmp_1_16563859_G_A | 17 | V>M | No | 1000Genomes | |
| ENSVATH01278290 | 21 | S>L | No | 1000Genomes | |
| ENSVATH01278290 | 21 | S>W | No | 1000Genomes | |
| tmp_1_16563875_G_C | 22 | C>S | No | 1000Genomes | |
| ENSVATH01278291 | 22 | C>W | No | 1000Genomes | |
| ENSVATH14208152 | 71 | V>F | No | 1000Genomes | |
| ENSVATH00078936 | 75 | K>T | No | 1000Genomes | |
| tmp_1_16564841_C_A | 109 | T>N | No | 1000Genomes | |
| tmp_1_16564852_C_A | 113 | R>S | No | 1000Genomes | |
| ENSVATH04851903 | 114 | G>R | No | 1000Genomes | |
| ENSVATH13330553 | 126 | S>T | No | 1000Genomes | |
| ENSVATH13330554 | 151 | G>S | No | 1000Genomes | |
| ENSVATH01278356 | 154 | S>A | No | 1000Genomes | |
| ENSVATH04851914 | 161 | V>L | No | 1000Genomes | |
| ENSVATH04851915 | 163 | M>L | No | 1000Genomes | |
| ENSVATH04851916 | 167 | L>F | No | 1000Genomes | |
| tmp_1_16565224_G_A | 176 | R>Q | No | 1000Genomes | |
| ENSVATH04851917 | 195 | D>N | No | 1000Genomes | |
| ENSVATH13330567 | 200 | Y>H | No | 1000Genomes | |
| tmp_1_16565317_G_T | 207 | R>I | No | 1000Genomes | |
| ENSVATH04851921 | 269 | L>F | No | 1000Genomes | |
| ENSVATH04851922 | 269 | L>P | No | 1000Genomes | |
| tmp_1_16565610_T_C | 274 | V>A | No | 1000Genomes | |
| ENSVATH04851925 | 294 | V>I | No | 1000Genomes | |
| tmp_1_16566210_A_T | 312 | R>W | No | 1000Genomes | |
| ENSVATH04851957 | 332 | P>L | No | 1000Genomes | |
| ENSVATH04851958 | 344 | K>Q | No | 1000Genomes | |
| ENSVATH04851959 | 344 | K>R | No | 1000Genomes | |
| tmp_1_16566312_C_A | 346 | P>T | No | 1000Genomes | |
| ENSVATH01278386 | 382 | W>L | No | 1000Genomes | |
| ENSVATH04851973 | 410 | F>V | No | 1000Genomes | |
| ENSVATH04851974 | 417 | G>E | No | 1000Genomes | |
| ENSVATH04851995 | 467 | R>Q | No | 1000Genomes | |
| tmp_1_16567362_A_G | 468 | K>R | No | 1000Genomes | |
| ENSVATH04851997 | 471 | H>L | No | 1000Genomes | |
| ENSVATH13330681 | 472 | K>N | No | 1000Genomes | |
| ENSVATH14208279 | 477 | L>R | No | 1000Genomes | |
| ENSVATH13330682 | 479 | D>Y | No | 1000Genomes |
No associated diseases with Q9MAR8
1 regional properties for Q9MAR8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| active_site | Serine carboxypeptidase, serine active site | 180 - 187 | IPR018202 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular region | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| serine-type carboxypeptidase activity | Catalysis of the hydrolysis of a single C-terminal amino acid residue from the C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| proteolysis | The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. |
3 homologous proteins in AiPD
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVGGKWRFLE | VAVVVMVLQW | SCDYNGNLAE | GFPVQDLVTK | LPGQPEVAFR | QFAGYVDIDV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KAGRSLFYYF | VEAEKQPHSK | PLTLWLNGGP | GCSSIGGGAF | TELGPFYPTG | DARGLRRNPK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SWNKASNLLF | VDSPAGVGWS | YSNTTSDYTT | GDESTAKDML | VFMLRWLEKF | PQFKTRNLFL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AGESYAGHYV | PQLADVILEY | NAQRSNRFKF | NLKGIAIGNP | LLKLDRDVPA | IYEFFWSHGM |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ISDELGLTIM | NQCDFEDYTF | TDSHNISKLC | EAAVNQAGTI | ITQYVNYYDI | LLDVCYPSLF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EQELRLKKMG | TRMSFGVDVC | MSFEEQLYLN | LPEVQKALHA | NRTKLPYEWS | MCSSLLNYKY |
| 370 | 380 | 390 | 400 | 410 | 420 |
| TDGNANMLPI | LKRIVKSKVP | VWVFSGDEDS | VIPLLGSRTL | VKELADDLNF | NTTVPYGAWF |
| 430 | 440 | 450 | 460 | 470 | |
| DKGQVGGWVV | EYGNLLTFAT | VRGAAHMVPY | SQPSRALHLF | TSFVLGRKLP | HKSPPALHD |