Q9D3S9
Gene name |
Cpvl |
Protein name |
Probable serine carboxypeptidase CPVL |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:71287 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9D3S9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9D3S9-F1 | Predicted | AlphaFoldDB |
26 variants for Q9D3S9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs29997413 | 16 | M>I | No | EVA | |
| rs3388814378 | 16 | M>V | No | EVA | |
| rs29997409 | 40 | D>N | No | EVA | |
| rs30002170 | 66 | S>N | No | EVA | |
| rs3388831350 | 74 | K>Q | No | EVA | |
| rs3388831863 | 91 | F>S | No | EVA | |
| rs3388809462 | 93 | W>C | No | EVA | |
| rs3388832985 | 95 | F>L | No | EVA | |
| rs3388829354 | 103 | D>G | No | EVA | |
| rs3388828608 | 162 | S>N | No | EVA | |
| rs3388828542 | 163 | F>I | No | EVA | |
| rs3388829362 | 176 | D>E | No | EVA | |
| rs3388835115 | 179 | Q>R | No | EVA | |
| rs3388832999 | 198 | N>K | No | EVA | |
| rs30001890 | 202 | V>I | No | EVA | |
| rs3388831353 | 221 | S>F | No | EVA | |
| rs3388814324 | 312 | G>* | No | EVA | |
| rs249981275 | 323 | T>M | No | EVA | |
| rs3388814371 | 334 | F>S | No | EVA | |
| rs3388819952 | 370 | K>* | No | EVA | |
| rs3388829395 | 405 | M>T | No | EVA | |
| rs29998042 | 414 | R>K | No | EVA | |
| rs3388829383 | 415 | R>K | No | EVA | |
| rs3412117896 | 417 | R>H | No | EVA | |
| rs3388828592 | 428 | N>T | No | EVA | |
| rs3388819949 | 435 | R>K | No | EVA |
No associated diseases with Q9D3S9
1 regional properties for Q9D3S9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| active_site | Serine carboxypeptidase, serine active site | 202 - 209 | IPR018202 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| serine-type carboxypeptidase activity | Catalysis of the hydrolysis of a single C-terminal amino acid residue from the C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| proteolysis | The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVRAKWKMVV | SLILFMVSPG | DGLFHAVYRS | ILVSQSFKGD | AGQPLFLSPY | IKNGKIKEGQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RKSMVSPFPG | MNDKSYAGYI | TVNQTYNSNL | FFWFFPARMQ | PEDAPVVLWL | QGGPGGSSMF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GLFVEHGPYI | ITSNMTVVAR | DFPWTFTLSM | LYIDNPVGTG | FSFTDHFQGY | ATSEDDVAQD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LYSALIQFFT | LFPEYAKNDF | YVTGESYAGK | YVPALAHYIH | SLNPVRKFKI | RLKGIAIGDA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YTDPESIIGG | YAAFLYEIGL | LDEQQQKYFQ | KQCSKCVKYI | KEQEWMKAFE | ILDKLLDGDV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TTGSSFFQNV | TGCTNYYNIL | QCTEPKEQSY | FAKFLTLPQV | RQAIHVGNQN | FSDGAEVEKH |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LREDTVKSVK | PWLSEIMNYY | KVLIYNGQLD | IIVAAALTER | SLMAMDWKGS | RAYRRARRKV |
| 430 | 440 | 450 | 460 | 470 | |
| WKIFKSDNEV | AGYVRRVGKF | HQVIVRGGGH | ILPYDQPMRS | FDMINRFIYD | RGWEPYNS |